EQRX EQRx Inc

Your Vote Counts! EQRX, INC. 50 HAMPSHIRE STREET CAMBRIDGE, MA 02139 UNITED STATES EQRX, INC. 2022 Annual Meeting Vote by September 29, 2022 11:59 PM ET You invested in EQRX, INC. and it’s time to vote! You have the right to vote on proposals being presented at the Annual Meeting. This is an important notice regarding the availability of proxy material for the stockholder meeting to be held on September 30, 2022. Vote Virtually at the Meeting* September 30, 2022 8:00 AM EDT Virtually at: www.virtualshareholdermeeting.com/EQRX2022 *Please check the meeting materials for any special requirements for meeting attendance. Smartphone users Point your camera here and vote without entering a control number V1.1 For complete information and to vote, visit www.ProxyVote.com Control # D90029-P79020 Get informed before you vote View the Notice and Proxy Statement and Annual Report online OR you can receive a free paper or email copy of the material(s) by requesting prior to September 16, 2022. If you would like to request a copy of the material(s) for this and/or future stockholder meetings, you may (1) visit www.ProxyVote.com, (2) call 1-800-579-1639 or (3) send an email to sendmaterial@proxyvote.com. If sending an email, please include your control number (indicated below) in the subject line. Unless requested, you will not otherwise receive a paper or email copy.

THIS IS NOT A VOTABLE BALLOT This is an overview of the proposals being presented at the upcoming stockholder meeting. Please follow the instructions on the reverse side to vote these important matters. Vote at www.ProxyVote.com Prefer to receive an email instead? While voting on www.ProxyVote.com, be sure to click “Sign up for E-delivery”. Voting Items Board Recommends D90030-P79020 1. Election of three class I directors to serve until the 2025 annual meeting of stockholders. Nominees: 1c. Sandra Horning 1a. Paul Berns 2. Ratification of the appointment of Ernst & Young LLP as our independent registered public accounting firm for the year ending December 31, 2022. 1b. Jorge Conde NOTE: Such other business as may properly come before the meeting or any adjournment or postponement thereof. For For For For