By Will Feuer

 

AstraZeneca PLC and Merck & Co. said its Lynparza drug was demonstrated in its Phase 3 trial to improve the overall survival of certain patients with high-risk early breast cancer who have been treated with neoadjuvant or adjuvant chemotherapy.

In the trial, called OlympiA, Lynparza reduced the risk of death by 32%, compared with when patients only received the placebo treatment, the companies said.

AstraZeneca said earlier this week that the drug was approved in the U.S. as an additional treatment for patients with early breast cancer who have already been treated with chemotherapy either before or after surgery after the drug reached its primary endpoint by significantly improving invasive disease-free survival.

Improving overall survival was a key secondary endpoint of the trial, the companies said.

 

Write to Will Feuer at Will.Feuer@wsj.com

 

(END) Dow Jones Newswires

March 16, 2022 14:16 ET (18:16 GMT)

Copyright (c) 2022 Dow Jones & Company, Inc.
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