By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- European stock markets traded broadly lower on Wednesday as the government shutdown in the U.S. moved into day two and investors awaited the latest policy decision from the European Central Bank.

The Stoxx Europe 600 index dropped 0.8% to 310.56, erasing a 0.8% gain from Tuesday.

Shares of Tesco PLC (TSCDY) gave up 3.3% after the supermarket chain reported a drop in first-half net profit as it is struggling to regain footing in the U.K. and faces sales declines in international markets.

Shares of Unilever PLC (UL) lost 1.6% after UBS cut the consumer-products firm to neutral from buy, with the analysts citing slowing demands in emerging markets on top of currency weakness.

"Whilst this does not invalidate the long term structural EM growth story, perhaps the market needs to revisit the growth algorithm one should apply. With Unilever positioning itself as 'the' emerging market company it will unavoidably find itself in the middle of this debate," the analysts said.

More broadly, political uncertainty was on the agenda in both Italy and the U.S. and hampered the trading sentiment in Europe. In Italy, Prime Minister Enrico Letta prepared to hold a vote of confidence in efforts to save the government after five ministers of Silvio Berlusconi's People of Freedom party resigned over the weekend.

Letta should win the confidence vote in the Chamber of Deputies, but is expected to struggle for support in the Senate, analysts at Société Générale said in a note. In recent days, however, Berlusconi has lost backing from some party members and deputy and party secretary Angelino Alfano said on Tuesday that members of the party should back Letta, according to media reports.

In the U.S., the government shutdown moved into a second day as law makers still didn't agree on a budget for the fiscal year, which started on Tuesday. Investors are growing increasingly worried that the impasse will go on longer than expected and may impact negotiations to raise the debt-ceiling in mid-October.

U.S. stock futures moved sharply lower.

Later in the day attention turns to the European Central Bank, which will announce its latest policy decision at 12:45 p.m. London time, or 7:45 a.m. Eastern Time, followed by ECB President Mario Draghi's news conference at 13:30 p.m. Analysts expect to keep the interest rate at a record low 0.5%. Read: ECB preview: European, U.S. politicians make life difficult for Mario Draghi

Among country-specific indexes in Europe, France's CAC 40 index lost 0.9% to 4,158.97, while Germany's DAX 30 index gave up 0.6% to 8,641.19. The U.K.'s FTSE 100 index erased 0.9% to 6,400.24.

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