Cardiome Announces Positive Interim Phase 2b Results for Oral Vernakalant and Engages Merrill Lynch as Strategic Advisor
17 März 2008 - 8:10AM
PR Newswire (US)
NASDAQ: CRME TSX: COM VANCOUVER, March 17 /PRNewswire-FirstCall/ --
Cardiome Pharma Corp. (NASDAQ:CRME/TSX:NASDAQ:COM) today announced
positive interim clinical results from its 90-day Phase 2b study of
vernakalant (oral). The interim analysis demonstrated statistically
significant efficacy for the patient group receiving 500mg b.i.d.
of vernakalant (oral) as compared to placebo. The safety data from
the interim analysis also suggests that vernakalant (oral) was
well-tolerated in the atrial fibrillation population studied during
the dosing period under analysis. A Kaplan-Meier analysis of the
446 patients included in the interim dataset demonstrated a
significant efficacy benefit for the 500mg dosing group as compared
to placebo (two-sided, p