OPRX OptimizeRx Corporation

OPTIMIZERx Corporation (PINKSHEETS: OPRX) today announced that on Monday November 10, 2008, the Company filed a Form S-1 Registration Statement with the United States Securities Exchange Commission.

David Harrell, CEO of OPTIMIZERx, commented, "The filing of our Form S-1 is simply the next step in providing transparency and accountability to our shareholders. When we completed our reverse merger in the spring, we committed to our shareholders that we would work diligently to become a reporting company. After we receive notice from the regulators that our registration statement is effective, and upon meeting the various listing requirements, our goal is to list the trading of our stock with NASDAQ."

About OPTIMIZERx Corporation

OPTIMIZERx provides unique platforms to help patients better afford and comply with their medicines therapies and healthcare products, while offering pharmaceutical and healthcare companies effective methods to expand patient awareness, access and adherence to their brands. The Company's consumer website, www.OPTIMIZERx.com, and its permanent subscriber base, continues to grow each month and is quickly becoming the preferred way to access branded prescription savings and support programs. Additionally, OPTIMIZERx has integrated and developed peripheral offerings, including OFFERx(TM) offer management system and the ADHERxE(TM) platform to allow more brands to participate in promoting a new trial or co-pay program. For additional information on OPTIMIZERx, including an investor fact sheet, see www.firstcapitalinvestors.com.

'SAFE HARBOR'

This press release contains forward-looking statements within the definition of Section 27A of the Securities Act of 1933, as amended and such section 21E of the Securities Act of 1934, amended. These forward-looking statements should not be used to make an investment decision. The words 'estimate,' 'possible' and 'seeking' and similar expressions identify forward-looking statements, which speak only as to the date the statement was made. The company undertakes no obligation to publicly update or revise any forward-looking statements, whether because of new information, future events, or otherwise. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted, or quantified. Future events and actual results could differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward-looking statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks.

Contact: Investor Relations First Capital Investors, Inc. Email Contact 321-221-2910