TEKLA WORLD HEALTHCARE FUND
SCHEDULE OF INVESTMENTS
JUNE 30, 2023 (Unaudited)
Non-Convertible Notes - 16.5% | |
Principal
Amount |
|
|
Value | |
France – 0.5% | |
|
|
|
|
|
| |
Sanofi, 3.63% due 06/19/28 | |
$ | 2,600,000 | | |
$ | 2,502,268 | |
| |
| | | |
| | |
Ireland – 0.3% | |
| | | |
| | |
Endo Dac/Endo Finance LLC/Endo Finco, Inc., 9.50% due 07/31/27 (a) | |
| 516,000 | | |
| 30,960 | |
Endo Dac/Endo Finance LLC/Endo Finco, Inc., 6.00% due 06/30/28 (a) | |
| 789,000 | | |
| 39,450 | |
Mallinckrodt International Finance S.A., 10.00% due 06/15/29(a) | |
| 997,897 | | |
| 152,179 | |
Shire Acquisitions Investments Ireland DAC, 3.20% due 09/23/26 | |
| 1,500,000 | | |
| 1,407,952 | |
| |
| | | |
| 1,630,541 | |
United Kingdom – 1.0% | |
| | | |
| | |
AstraZeneca plc, 3.38% due 11/16/25 | |
| 5,000,000 | | |
| 4,806,143 | |
| |
| | | |
| | |
United States – 14.7% | |
| | | |
| | |
Abbott Laboratories, 4.75% due 11/30/36 | |
| 5,652,000 | | |
| 5,661,694 | |
AbbVie, Inc., 4.50% due 05/14/35 | |
| 3,200,000 | | |
| 3,038,876 | |
AbbVie, Inc., 4.45% due 05/14/46 | |
| 1,705,000 | | |
| 1,498,688 | |
Amgen, Inc., 3.63% due 05/22/24 | |
| 2,000,000 | | |
| 1,965,036 | |
Amgen, Inc., 2.00% due 01/15/32 | |
| 1,555,000 | | |
| 1,227,313 | |
Baxalta, Inc., 4.00% due 06/23/25 | |
| 831,000 | | |
| 806,048 | |
Becton, Dickinson and Co., 3.73% due 12/15/24 | |
| 328,000 | | |
| 318,383 | |
Bristol-Myers Squibb Co., 3.40% due 07/26/29 | |
| 1,400,000 | | |
| 1,299,905 | |
CVS Health Corp., 1.88% due 02/28/31 | |
| 2,448,000 | | |
| 1,942,811 | |
DH Europe Finance II Sarl, 3.25% due 11/15/39 | |
| 985,000 | | |
| 799,390 | |
Elevance Health, Inc., 2.55% due 03/15/31 | |
| 3,200,000 | | |
| 2,686,568 | |
EMD Finance LLC, 3.25% due 03/19/25 (a) | |
| 4,000,000 | | |
| 3,833,134 | |
GlaxoSmithKline Capital plc, 3.00% due 06/01/24 | |
| 1,400,000 | | |
| 1,367,891 | |
GlaxoSmithKline Capital plc, 3.38% due 06/01/29 | |
| 1,000,000 | | |
| 928,197 | |
HCA, Inc., 5.38% due 02/01/25 | |
| 1,250,000 | | |
| 1,238,728 | |
HCA, Inc., 5.25% due 04/15/25 | |
| 600,000 | | |
| 592,162 | |
IQVIA, Inc., 5.00% due 05/15/27 (a) | |
| 710,000 | | |
| 682,976 | |
Johnson & Johnson, 2.45% due 03/01/26 | |
| 4,300,000 | | |
| 4,059,820 | |
Johnson & Johnson, 2.90% due 01/15/28 | |
| 1,400,000 | | |
| 1,316,745 | |
Laboratory Corporation of America Holdings, 3.60% due 02/01/25 | |
| 1,400,000 | | |
| 1,352,648 | |
Medtronic, Inc., 4.38% due 03/15/35 | |
| 1,675,000 | | |
| 1,609,542 | |
Merck & Co., Inc., 2.75% due 02/10/25 | |
| 1,463,000 | | |
| 1,407,707 | |
Novartis Capital Corp., 3.40% due 05/06/24 | |
| 2,115,000 | | |
| 2,078,521 | |
Par Pharmaceutical, Inc., 7.50% due 04/01/27 (a) | |
| 193,000 | | |
| 142,633 | |
Pfizer, Inc., 3.45% due 03/15/29 | |
| 5,300,000 | | |
| 4,986,630 | |
Pfizer, Inc., 4.00% due 12/15/36 | |
| 1,800,000 | | |
| 1,676,203 | |
Senior Housing Properties Trust, 4.75% due 05/01/24 | |
| 1,750,000 | | |
| 1,629,478 | |
Syneos Health, Inc., 3.63% due 01/15/29 (a) | |
| 2,300,000 | | |
| 2,248,434 | |
The Cigna Group, 3.50% due 06/15/24 | |
| 2,785,000 | | |
| 2,728,126 | |
The Cigna Group, 2.38% due 03/15/31 | |
| 3,200,000 | | |
| 2,685,467 | |
UnitedHealth Group, Inc., 3.88% due 12/15/28 | |
| 2,560,000 | | |
| 2,451,429 | |
UnitedHealth Group, Inc., 4.20% due 05/15/32 | |
| 6,060,000 | | |
| 5,782,822 | |
Zimmer Biomet Holdings, Inc., 4.25% due 08/15/35 | |
| 5,000,000 | | |
| 4,316,807 | |
| |
| | | |
| 70,360,812 | |
Total
Non-Convertible Notes (Cost $86,601,884) | |
| | | |
| 79,299,764 | |
THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.
Convertible Preferreds (Restricted) (b) (c) - 1.8% | |
Shares |
|
|
Value | |
France – 0.5% | |
|
|
|
|
|
| |
Amolyt Pharma SAS Series C | |
| 686,916 | | |
$ | 1,604,065 | |
Flamingo Therapeutics, Inc. Series A3 | |
| 136,337 | | |
| 908,991 | |
| |
| | | |
| 2,513,056 | |
Ireland – 0.5% | |
| | | |
| | |
Priothera Ltd. Series A, 6.00% | |
| 194,134 | | |
| 2,118,391 | |
| |
| | | |
| | |
United States – 0.8% | |
| | | |
| | |
Aristea Therapeutics, Inc. Series B, 8.00% | |
| 290,187 | | |
| 1,600,004 | |
Endeavor Biomedicines, Inc. Series B, 8.00% | |
| 424,079 | | |
| 1,999,999 | |
IO Light Holdings, Inc. Series A2 | |
| 101,839 | | |
| 290,037 | |
| |
| | | |
| 3,890,040 | |
Total Convertible Preferreds (Cost $10,955,883) | |
| | | |
| 8,521,487 | |
| |
| | | |
| | |
Common Stocks - 103.1% | |
| | | |
| | |
Australia – 1.5% | |
| | | |
| | |
CSL Ltd. | |
| 38,719 | | |
| 7,154,370 | |
| |
| | | |
| | |
Canada – 0.0% | |
| | | |
| | |
Fusion Pharmaceuticals, Inc. (c) | |
| 7,378 | | |
| 34,529 | |
Fusion Pharmaceuticals, Inc. (Restricted) (b) (c) | |
| 3,689 | | |
| 15,538 | |
| |
| | | |
| 50,067 | |
China – 0.2% | |
| | | |
| | |
BeiGene Ltd. ADR (c) | |
| 4,114 | | |
| 733,526 | |
I-Mab ADR (c) | |
| 38,848 | | |
| 116,156 | |
| |
| | | |
| 849,682 | |
Denmark – 4.4% | |
| | | |
| | |
MorphoSys AG ADR (c) | |
| 177,191 | | |
| 1,323,617 | |
Novo Nordisk A/S ADR | |
| 122,777 | | |
| 19,869,002 | |
| |
| | | |
| 21,192,619 | |
France – 1.4% | |
| | | |
| | |
Sanofi ADR | |
| 123,454 | | |
| 6,654,170 | |
| |
| | | |
| | |
Germany – 1.5% | |
| | | |
| | |
Affimed N.V. (c) | |
| 10,000 | | |
| 5,982 | |
Bayer AG | |
| 131,684 | | |
| 7,280,956 | |
| |
| | | |
| 7,286,938 | |
Ireland – 0.5% | |
| | | |
| | |
ICON plc (c) | |
| 6,534 | | |
| 1,634,807 | |
Perrigo Co. plc | |
| 15,882 | | |
| 539,194 | |
| |
| | | |
| 2,174,001 | |
Israel – 0.1% | |
| | | |
| | |
Teva Pharmaceutical Industries Ltd. ADR (c) | |
| 90,281 | | |
| 679,816 | |
| |
| | | |
| | |
Japan – 1.8% | |
| | | |
| | |
Astellas Pharma, Inc. | |
| 44,419 | | |
| 661,537 | |
Daiichi Sankyo Co., Ltd. | |
| 54,075 | | |
| 1,705,127 | |
Eisai Co., Ltd. | |
| 6,830 | | |
| 460,272 | |
Hoya Corp. | |
| 9,682 | | |
| 1,145,709 | |
M3, Inc. | |
| 7,436 | | |
| 160,217 | |
Olympus Corp. | |
| 28,940 | | |
| 454,472 | |
Ono Pharmaceutical Co., Ltd. | |
| 11,330 | | |
| 204,622 | |
Otsuka Holdings Co., Ltd. | |
| 20,808 | | |
| 760,102 | |
Shionogi & Co., Ltd. | |
| 7,707 | | |
| 324,207 | |
Sysmex Corp. | |
| 3,715 | | |
| 252,361 | |
THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.
| |
Shares |
|
|
Value | |
Japan – continued | |
| | | |
| | |
Takeda Pharmaceuticals Co., Ltd. | |
| 9,600 | | |
$ | 301,183 | |
Takeda Pharmaceuticals Co., Ltd. ADR (d) | |
| 105,073 | | |
| 1,650,697 | |
Terumo Corp. | |
| 17,288 | | |
| 546,574 | |
| |
| | | |
| 8,627,080 | |
Netherlands – 1.0% | |
| | | |
| | |
argenx SE ADR (c) | |
| 6,255 | | |
| 2,437,761 | |
Koninklijke Philips N.V. | |
| 114,765 | | |
| 2,489,253 | |
| |
| | | |
| 4,927,014 | |
Switzerland – 9.6% | |
| | | |
| | |
Lonza Group AG | |
| 12,711 | | |
| 7,575,049 | |
Novartis AG ADR | |
| 136,225 | | |
| 13,746,464 | |
Oculis Holding AG (Restricted) (b) | |
| 304,333 | | |
| 3,388,139 | |
Roche Holding AG ADR | |
| 562,829 | | |
| 21,500,068 | |
| |
| | | |
| 46,209,720 | |
United Kingdom – 4.6% | |
| | | |
| | |
AstraZeneca plc ADR | |
| 226,704 | | |
| 16,225,205 | |
Smith & Nephew plc ADR (d) | |
| 181,710 | | |
| 5,860,148 | |
| |
| | | |
| 22,085,353 | |
United States – 76.5% | |
| | | |
| | |
Abbott Laboratories (e) | |
| 130,365 | | |
| 14,212,392 | |
AbbVie, Inc. (e) | |
| 132,594 | | |
| 17,864,390 | |
Acadia Healthcare Co., Inc. (c) | |
| 25,973 | | |
| 2,068,490 | |
Amgen, Inc. (e) | |
| 64,224 | | |
| 14,259,012 | |
Ardelyx, Inc. (c) (d) | |
| 282,002 | | |
| 955,987 | |
Avantor, Inc. (c) | |
| 142,388 | | |
| 2,924,649 | |
Baxter International, Inc. | |
| 86,526 | | |
| 3,942,125 | |
Biogen, Inc. (c) | |
| 15,208 | | |
| 4,331,999 | |
Boston Scientific Corp. (c) (e) | |
| 172,145 | | |
| 9,311,323 | |
Bristol-Myers Squibb Co. | |
| 100,088 | | |
| 6,400,628 | |
Charles River Laboratories International, Inc. (c) (e) | |
| 21,364 | | |
| 4,491,781 | |
Community Health Systems, Inc. (c) | |
| 8,700 | | |
| 38,280 | |
Community Healthcare Trust, Inc. | |
| 14,900 | | |
| 491,998 | |
Danaher Corp. | |
| 37,903 | | |
| 9,096,720 | |
DexCom, Inc. (c) (e) | |
| 64,567 | | |
| 8,297,505 | |
Diversified Healthcare Trust REIT | |
| 63,841 | | |
| 143,642 | |
Edwards Lifesciences Corp. (c) | |
| 51,018 | | |
| 4,812,528 | |
Elevance Health, Inc. | |
| 28,373 | | |
| 12,605,840 | |
Eli Lilly & Co. | |
| 37,180 | | |
| 17,436,676 | |
Galera Therapeutics, Inc. (c) | |
| 161,709 | | |
| 504,532 | |
Gilead Sciences, Inc. | |
| 87,662 | | |
| 6,756,110 | |
Global Medical REIT, Inc. | |
| 143,229 | | |
| 1,307,681 | |
GSK plc ADR | |
| 41,852 | | |
| 1,491,605 | |
Guardant Health, Inc. (c) | |
| 53,333 | | |
| 1,909,321 | |
HCA Healthcare, Inc. | |
| 16,303 | | |
| 4,947,634 | |
Healthcare Realty Trust, Inc. | |
| 149,567 | | |
| 2,820,834 | |
Healthpeak Properties, Inc. | |
| 83,601 | | |
| 1,680,380 | |
Humana, Inc. (e) | |
| 9,425 | | |
| 4,214,200 | |
IDEXX Laboratories, Inc. (c) | |
| 15,748 | | |
| 7,909,118 | |
Illumina, Inc. (c) (e) | |
| 35,007 | | |
| 6,563,462 | |
Insulet Corp. (c) | |
| 10,283 | | |
| 2,965,000 | |
Intuitive Surgical, Inc. (c) | |
| 17,195 | | |
| 5,879,658 | |
IQVIA Holdings, Inc. (c) (e) | |
| 28,415 | | |
| 6,386,840 | |
Johnson & Johnson (e) | |
| 182,963 | | |
| 30,284,036 | |
LTC Properties, Inc. | |
| 46,903 | | |
| 1,548,737 | |
Mallinckrodt plc (c) | |
| 35,048 | | |
| 41,357 | |
THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.
| |
Shares |
|
|
Value | |
United States - continued | |
| | | |
| | |
McKesson Corp. (e) | |
| 10,401 | | |
$ | 4,444,451 | |
Medical Properties Trust, Inc. (d) | |
| 145,186 | | |
| 1,344,422 | |
Medtronic plc (e) | |
| 79,482 | | |
| 7,002,364 | |
Merck & Co., Inc. (e) | |
| 189,992 | | |
| 21,923,177 | |
Moderna, Inc. (c) | |
| 14,416 | | |
| 1,751,544 | |
Molina Healthcare, Inc. (c) (e) | |
| 14,583 | | |
| 4,392,983 | |
National Health Investors, Inc. | |
| 4,442 | | |
| 232,850 | |
Omega Healthcare Investors, Inc. | |
| 71,075 | | |
| 2,181,292 | |
Pfizer, Inc. (e) | |
| 429,273 | | |
| 15,745,734 | |
Physicians Realty Trust | |
| 291,309 | | |
| 4,075,413 | |
R1 RCM, Inc. (c) | |
| 124,297 | | |
| 2,293,280 | |
Regeneron Pharmaceuticals, Inc. (c) | |
| 9,088 | | |
| 6,530,091 | |
ResMed, Inc. | |
| 10,104 | | |
| 2,207,724 | |
Sabra Health Care REIT, Inc. | |
| 90,781 | | |
| 1,068,492 | |
Stryker Corp. | |
| 16,321 | | |
| 4,979,374 | |
The Cigna Group (e) | |
| 21,036 | | |
| 5,902,702 | |
Thermo Fisher Scientific, Inc. (e) | |
| 24,289 | | |
| 12,672,786 | |
UnitedHealth Group, Inc. | |
| 55,428 | | |
| 26,640,914 | |
Universal Health Realty Income Trust | |
| 8,183 | | |
| 389,347 | |
Ventas, Inc. | |
| 66,681 | | |
| 3,152,011 | |
Veradigm, Inc. (c) | |
| 90,363 | | |
| 1,138,574 | |
Vertex Pharmaceuticals, Inc. (c) | |
| 12,833 | | |
| 4,516,061 | |
Welltower, Inc. | |
| 41,484 | | |
| 3,355,641 | |
West Pharmaceutical Services, Inc. | |
| 3,370 | | |
| 1,288,924 | |
Zimmer Biomet Holdings, Inc. (e) | |
| 23,986 | | |
| 3,492,362 | |
Zoetis, Inc. | |
| 29,308 | | |
| 5,047,131 | |
| |
| | | |
| 368,666,114 | |
Total
Common Stocks (Cost $482,502,401) | |
| | | |
| 496,556,944 | |
| |
Principal
Amount |
|
| |
Short-Term Investments– 4.0% | |
| | | |
| | |
MUFG Bank Ltd. Commercial Paper, 5.00%, due 07/06/23 | |
$ | 5,000,000 | | |
| 4,996,528 | |
Repurchase Agreement, Fixed Income Clearing Corp., repurchase value $11,885,505, 1.52%, dated 06/30/23, due 07/03/23 (collateralized by U.S. Treasury Note 1.500%, due 01/31/27, market value $12,121,761) | |
| 11,884,000 | | |
| 11,884,000 | |
| |
| | | |
| 16,880,528 | |
| |
Shares | | |
Value | |
State Street Institutional U.S. Government Money Market Fund, Institutional Class, 5.03% (f) | |
| 2,657,701 | | |
| 2,657,701 | |
Total Short-Term Investments (Cost $19,538,229) | |
| | | |
| 19,538,229 | |
Total Investments Before
Milestone Interest – 125.4% (Cost $599,598,397) | |
| | | |
| 603,916,424 | |
| |
Interests | | |
| |
Milestone Interest (Restricted) (b) (c) – 0.0% | |
| | | |
| | |
Biotechnology – 0.0% | |
| | | |
| | |
Rainier Therapeutics Milestone Interest | |
| 1 | | |
| 0 | |
Total Milestone
Interest (Cost $143,115) | |
| | | |
| 0 | |
|
Number of
Contracts (100
shares each)/
Notional Amount
($) | |
| |
Option Contracts Written – (0.1)% |
| |
| |
Call Option Contracts Written – (0.1)% | |
| |
| | |
Abbott Laboratories Aug23 115 Call | |
190/(2,185,000) | |
| (14,820 | ) |
Abbott Laboratories Jul23 112 Call | |
193/(2,161,600) | |
| (15,826 | ) |
AbbVie, Inc. Aug23 140 Call | |
129/(1,806,000) | |
| (23,091 | ) |
AbbVie, Inc. Jul23 135 Call | |
131/(1,768,500) | |
| (22,401 | ) |
THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.
|
|
Number of
Contracts (100
shares each)/
Notional Amount
($) | |
Value | |
Amgen, Inc. Aug23 235 Call | |
94/(2,209,000) | |
$ | (17,954 | ) |
Amgen, Inc. Jul23 230 Call | |
94/(2,162,000) | |
| (8,836 | ) |
Boston Scientific Corp. Aug23 57.5 Call | |
165/(948,750) | |
| (6,435 | ) |
Charles River Laboratories International, Inc. Aug23 230 Call | |
20/(460,000) | |
| (7,800 | ) |
DexCom, Inc. Aug23 140 Call | |
63/(882,000) | |
| (17,010 | ) |
DexCom, Inc. Jul23 135 Call | |
63/(850,500) | |
| (7,875 | ) |
Humana, Inc. Aug23 470 Call | |
13/(611,000) | |
| (8,580 | ) |
Humana, Inc. Jul23 460 Call | |
13/(598,000) | |
| (5,070 | ) |
Illumina, Inc. Aug23 200 Call | |
34/(680,000) | |
| (22,440 | ) |
IQVIA Holdings, Inc. Aug23 230 Call | |
27/(621,000) | |
| (17,388 | ) |
Johnson & Johnson Aug23 170 Call | |
179/(3,043,000) | |
| (29,535 | ) |
Johnson & Johnson Jul23 165 Call | |
179/(2,953,500) | |
| (51,731 | ) |
McKesson Corp. Aug23 440 Call | |
10/(440,000) | |
| (9,000 | ) |
Medtronic plc Aug23 90 Call | |
62/(558,000) | |
| (9,982 | ) |
Merck & Co., Inc. Aug23 120 Call | |
185/(2,220,000) | |
| (28,490 | ) |
Merck & Co., Inc. Jul23 115 Call | |
187/(2,150,500) | |
| (42,823 | ) |
Molina Healthcare, Inc. Aug23 310 Call | |
14/(434,000) | |
| (12,950 | ) |
Pfizer, Inc. Aug23 37.5 Call | |
620/(2,325,000) | |
| (44,020 | ) |
Pfizer, Inc. Jul23 37.5 Call | |
637/(2,388,750) | |
| (21,021 | ) |
The Cigna Group Aug23 290 Call | |
30/(870,000) | |
| (20,400 | ) |
The Cigna Group Jul23 290 Call | |
31/(899,000) | |
| (6,045 | ) |
Thermo Fisher Scientific, Inc. Aug23 540 Call | |
30/(1,620,000) | |
| (32,040 | ) |
Thermo Fisher Scientific, Inc. Jul23 530 Call | |
30/(1,590,000) | |
| (20,220 | ) |
Zimmer Biomet Holdings, Inc. Aug23 155 Call | |
23/(356,500) | |
| (3,680 | ) |
Total
Option Contracts Written (Premiums received ($353,833)) | |
| |
| (527,463 | ) |
Total
Investments - 125.3% (Cost $599,387,679) | |
| |
| 603,388,961 | |
Other Liabilities in Excess of Assets - (25.3)% | |
| |
| (121,671,996 | ) |
Net Assets - 100% | |
| |
$ | 481,716,965 | |
The percentage shown for each investment category in the Schedule
of Investments is based on net assets.
(a) | Security exempt from registration under Rule 144A of the
Securities Act of 1933, as amended. These securities may be resold in transactions exempt from registration, normally to qualified institutional
buyers. |
(b) | Security fair valued using significant unobservable inputs.
See Investment Valuation and Fair Value Measurements. |
(c) | Non-income producing security. |
(d) | All or a portion of this security is on loan as of June 30,
2023. |
(e) | A portion of security is pledged as collateral for call options
written. |
(f) | This security represents the investment of cash collateral received
for securities lending and is a registered investment company advised by State Street Global Advisors. The rate shown is the annualized
seven-day yield as of June 30, 2023. |
| |
ADR | American Depository Receipt |
The following forward contracts were held as of June 30, 2023:
Description | |
Counterparty | |
Settlement Date | |
Currency | |
Settlement Value (in USD) | | |
Current Value | | |
Unrealized Gain/(Loss) | |
Contracts Sold: | |
| |
| |
| | | |
| |
| | | |
| | | |
| | |
Australian Dollar | |
Goldman Sachs Bank | |
07/31/23 | |
| 4,572,304 | | |
AUD | |
$ | 3,074,335 | | |
$ | 3,048,091 | | |
$ | 26,244 | |
British Pound | |
Goldman Sachs Bank | |
07/31/23 | |
| 9,440,375 | | |
GBP | |
| 12,039,365 | | |
| 11,991,490 | | |
| 47,875 | |
Danish Krone | |
Goldman Sachs Bank | |
07/31/23 | |
| 48,474,501 | | |
DKK | |
| 7,130,521 | | |
| 7,114,881 | | |
| 15,640 | |
Euro | |
Goldman Sachs Bank | |
07/31/23 | |
| 11,686,116 | | |
EUR | |
| 12,797,945 | | |
| 12,768,099 | | |
| 29,846 | |
Israeli Sheqel | |
Goldman Sachs Bank | |
07/31/23 | |
| 4,457,647 | | |
ILS | |
| 1,231,420 | | |
| 1,203,461 | | |
| 27,959 | |
Japanese Yen | |
Goldman Sachs Bank | |
07/31/23 | |
| 523,322,125 | | |
JPY | |
| 3,665,985 | | |
| 3,640,975 | | |
| 25,010 | |
Swiss Franc | |
Goldman Sachs Bank | |
07/31/23 | |
| 20,140,361 | | |
CHF | |
| 22,588,878 | | |
| 22,561,393 | | |
| 27,485 | |
| |
| |
| |
| | | |
| |
| | | |
$ | 62,328,390 | | |
$ | 200,059 | |
THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.
Investment Valuation
Shares of publicly
traded companies listed on national securities exchanges or trading in the over-the-counter market are typically valued at the last sale
price, as of the close of trading, generally 4 p.m., Eastern Time. The Fund holds securities, currencies and other assets that are denominated
in a foreign currency. The Fund will normally use the currency exchange rates as of 4:00 p.m. (Eastern Time) when valuing such assets.
The Board of Trustees of the Fund (the Trustees) has established and approved fair valuation policies and procedures with respect to securities
for which quoted prices may not be available or which do not reflect fair value. Convertible, corporate and government bonds are valued
using a third-party pricing service. Convertible bonds are valued using this pricing service only on days when there is no sale reported.
Puts and calls generally are valued at the close of regular trading on the securities or commodities exchange on which they are primarily
traded. Options on securities generally are valued at their last sale price in the case of exchange traded options or, in the case of
OTC-traded options, the average of the last sale price as obtained from two or more dealers unless there is only one dealer, in which
case that dealer’s price is used. Forward foreign currency contracts are valued on the basis of the value of the underlying currencies
at the prevailing forward exchange rates. Restricted securities of companies that are publicly traded are typically valued based on the
closing market quote on the valuation date adjusted for the impact of the restriction as determined in good faith by Tekla Capital Management
LLC (the Adviser) also using fair valuation policies and procedures approved by the Trustees described below. Short-term investments with
a maturity of 60 days or less are generally valued at amortized cost, which approximates fair value.
Convertible preferred shares, warrants
or convertible note interests in private companies, milestone interests and other restricted securities, as well as shares of publicly
traded companies for which market quotations are not readily available, such as stocks for which trading has been halted or for which
there are no current day sales, or which do not reflect fair value, are typically valued in good faith, based upon the recommendations
made by the Adviser pursuant to fair valuation policies and procedures approved by the Trustees.
The Adviser has a Valuation
Sub-Committee comprised of senior management which reports to the Valuation Committee of the Board at least quarterly. Each fair value
determination is based on a consideration of relevant factors, including both observable and unobservable inputs. Observable and unobservable
inputs may include (i) the existence of any contractual restrictions on the disposition of securities; (ii) information obtained
from the company, which may include an analysis of the company’s financial statements products, intended markets or technologies;
(iii) the price of the same or similar security negotiated at arm’s length in an issuer’s completed subsequent round
of financing; (iv) the price and extent of public trading in similar securities of the issuer or of comparable companies; or (v) a
probability and time value adjusted analysis of contractual terms. Where available and appropriate, multiple valuation methodologies are
applied to confirm fair value. Significant unobservable inputs identified by the Adviser are often used in the fair value determination.
A significant change in any of these inputs may result in a significant change in the fair value measurement. Due to the uncertainty inherent
in the valuation process, such estimates of fair value may differ significantly from the values that would have been used had a ready
market for the investments existed, and differences could be material. Additionally, changes in the market environment and other events
that may occur over the life of the investments may cause the gains or losses ultimately realized on these investments to be different
from the valuations used at the date of this schedule of investments.
Federal Income Tax Cost
At
June 30, 2023, the cost of securities for Federal income tax purposes was $600,801,335. The net unrealized gain on securities
held by the Fund was $2,587,626, including gross unrealized gain of $70,401,918 and gross unrealized loss of $67,814,292.
Securities Lending
The Fund may lend its securities to
approved borrowers to earn additional income. The Fund receives cash collateral from the borrower and the initial collateral received
by the Fund is required to have a value of at least 102% of the current value of the loaned securities traded on U.S. exchanges, and a
value of at least 105% for all other securities. The Fund will invest its cash collateral in State Street Institutional U.S. Government
Money Market Fund (SAHXX), which is registered with the Securities and Exchange Commission (SEC) as an investment company. SAHXX invests
substantially all of its assets in the State Street U.S. Government Money Market Portfolio. The Fund will receive the benefit of any gains
and bear any losses generated by SAHXX with respect to the cash collateral.
The Fund has the right to recall loaned securities on demand.
If a borrower fails to return loaned securities when due, then the lending agent is responsible and indemnifies the Fund for the lent
securities. The lending agent uses the collateral received from the borrower to purchase replacement securities of the same issue, type,
class and series of the loaned securities. If the value of the collateral is less than the purchase cost of replacement securities, the
lending agent is responsible for satisfying the shortfall but only to the extent that the shortfall is not due to any decrease in the
value of SAHXX.
Although
the risk of loss on securities lent is mitigated by receiving collateral from the borrower and through lending agent indemnification,
the Fund could experience a delay in recovering securities or could experience a lower than expected return if the borrower fails to return
the securities on a timely basis. The Fund receives compensation for lending its securities by retaining a portion of the return on the
investment of the collateral and compensation from fees earned from borrowers of the securities. Securities lending income received by
the Fund is net of fees retained by the securities lending agent. Net income received from SAHXX is a component of securities lending
income as recorded by the Fund.
As of June 30, 2023, the Fund loaned securities valued
at $2,609,145 and received $2,657,701 of cash collateral.
Forward Contracts
Forward
contracts involve the purchase or sale of a specific quantity of a commodity, government security, foreign currency, or other asset at
a specified price, with delivery and settlement at a specified future date. Because it is a completed contract, a purchase forward contract
can be a cover for the sale of a futures contract. The Fund may enter into forward contracts for hedging purposes and non-hedging purposes
(i.e., to increase returns). Forward contracts may be used by the Fund for hedging purposes to protect against uncertainty in the level
of future foreign currency exchange rates, such as when the Fund anticipates purchasing or selling a foreign security. Forward contracts
may also be used to attempt to protect the value of the Fund’s existing holdings of foreign securities. Forward contracts may also
be used for non-hedging purposes to pursue the Fund’s investment objective. There is no requirement that the Fund hedge all
or any portion of its exposure to foreign currency risks.
Fair Value Measurements
The Fund uses a three-tier hierarchy
to prioritize the assumptions, referred to as inputs, used in valuation techniques to measure fair value. The three-tier hierarchy of
inputs is summarized in the three broad levels. Level 1 includes quoted prices in active markets for identical investments. Level 2 includes
prices determined using other significant observable inputs (including quoted prices for similar investments, interest rates, credit risk, etc.).
The independent pricing vendor may value bank loans and debt securities at an evaluated bid price by employing methodologies that utilize
actual market transactions, broker-supplied valuations, and/or other methodologies designed to identify the market value for such securities
and such securities are considered Level 2 in the fair value hierarchy. Level 3 includes prices determined using significant unobservable
inputs (including the Fund’s own assumptions in determining the fair value of investments). These inputs or methodology used for
valuing securities are not necessarily an indication of the risk associated with investing in those securities.
For
the period ended June 30, 2023, there were no transfers between levels.
The following is a summary of the levels used as of June 30, 2023
to value the Fund’s investments.
Assets at Value | |
Level 1 | | |
Level 2 | | |
Level 3 | | |
Total | |
Non-convertible Notes | |
| | | |
| | | |
| | | |
| | |
France | |
$ | - | | |
$ | 2,502,268 | | |
$ | - | | |
$ | 2,502,268 | |
Ireland | |
| - | | |
| 1,630,541 | | |
| - | | |
| 1,630,541 | |
United Kingdom | |
| - | | |
| 4,806,143 | | |
| - | | |
| 4,806,143 | |
United States | |
| - | | |
| 70,360,812 | | |
| - | | |
| 70,360,812 | |
Convertible Preferreds | |
| | | |
| | | |
| | | |
| | |
France | |
| - | | |
| - | | |
| 2,513,056 | | |
| 2,513,056 | |
Ireland | |
| - | | |
| - | | |
| 2,118,391 | | |
| 2,118,391 | |
United States | |
| - | | |
| - | | |
| 3,890,040 | | |
| 3,890,040 | |
Common Stocks | |
| | | |
| | | |
| | | |
| | |
Australia | |
| 7,154,370 | | |
| - | | |
| - | | |
| 7,154,370 | |
Canada | |
| 34,529 | | |
| 15,538 | | |
| - | | |
| 50,067 | |
China | |
| 849,682 | | |
| - | | |
| - | | |
| 849,682 | |
Denmark | |
| 21,192,619 | | |
| - | | |
| - | | |
| 21,192,619 | |
France | |
| 6,654,170 | | |
| - | | |
| - | | |
| 6,654,170 | |
Germany | |
| 7,286,938 | | |
| - | | |
| - | | |
| 7,286,938 | |
Ireland | |
| 2,174,001 | | |
| - | | |
| - | | |
| 2,174,001 | |
Israel | |
| 679,816 | | |
| - | | |
| - | | |
| 679,816 | |
Japan | |
| 8,627,080 | | |
| - | | |
| - | | |
| 8,627,080 | |
Netherlands | |
| 4,927,014 | | |
| - | | |
| - | | |
| 4,927,014 | |
Switzerland | |
| 42,821,581 | | |
| 3,388,139 | | |
| - | | |
| 46,209,720 | |
United Kingdom | |
| 22,085,353 | | |
| - | | |
| - | | |
| 22,085,353 | |
United States | |
| 368,666,114 | | |
| - | | |
| - | | |
| 368,666,114 | |
Short-term Investments | |
| 2,657,701 | | |
| 16,880,528 | | |
| - | | |
| 19,538,229 | |
Milestone Interest | |
| | | |
| | | |
| | | |
| | |
United States | |
| - | | |
| - | | |
| 0 | * | |
| 0 | * |
Total | |
$ | 495,810,968 | | |
$ | 99,583,969 | | |
$ | 8,521,487 | | |
$ | 603,916,424 | |
Assets | |
| | | |
| | | |
| | | |
| | |
Forward Currency Contracts | |
$ | - | | |
$ | 200,059 | | |
$ | - | | |
$ | 200,059 | |
Liabilities | |
| | | |
| | | |
| | | |
| | |
Options Contracts Written | |
| (527,463 | ) | |
| - | | |
| - | | |
| (527,463 | ) |
Total | |
$ | (527,463 | ) | |
$ | 200,059 | | |
$ | - | | |
$ | (327,404 | ) |
* Represents security valued at zero.
The following is a reconciliation of Level 3 assets
for which significant unobservable inputs were used to determine fair value.
Investments in Securities | |
Balance as of
September 30,
2022 | | |
Net realized gain (loss) and change in
unrealized
appreciation (depreciation) | | |
Cost of purchases and conversions | | |
Proceeds from sales and conversions | | |
Net transfers into (out of) Level 3 | | |
Balance as
of June 30,
2023 | |
Convertible Preferreds | |
| | | |
| | | |
| | | |
| | | |
| | | |
| | |
France | |
$ | 960,713 | | |
$ | (56,152 | ) | |
$ | 1,608,495 | | |
$ | — | | |
$ | — | | |
$ | 2,513,056 | |
Ireland | |
| 1,902,611 | | |
| 215,780 | | |
| — | | |
| — | | |
| — | | |
| 2,118,391 | |
Switzerland | |
| 2,047,583 | | |
| (336,172 | ) | |
| — | | |
| (1,711,411 | ) | |
| — | | |
| — | |
United States | |
| 3,943,709 | | |
| (53,851 | ) | |
| 182 | | |
| — | | |
| — | | |
| 3,890,040 | |
Milestone Interest | |
| | | |
| | | |
| | | |
| | | |
| | | |
| | |
United States | |
| 138,520 | | |
| (138,520 | ) | |
| — | | |
| — | | |
| — | | |
| 0 | * |
Total | |
$ | 8,993,136 | | |
$ | (368,915 | ) | |
$ | 1,608,677 | | |
$ | (1,711,411 | ) | |
$ | — | | |
$ | 8,521,487 | |
| |
| | | |
| | | |
| | | |
| | | |
| | | |
| | |
Net change in unrealized appreciation (depreciation) from investments still held as of June 30, 2023 | | |
| | | |
$ | (32,743) | |
* Represents security valued at zero.
The following is a quantitative disclosure about significant unobservable inputs used in the determination of the fair value of Level
3 assets.
| |
Fair Value at June 30, 2023 | | |
Valuation Technique | |
Unobservable Input | |
Range (Weighted Average) |
Convertible Preferreds | |
$ | 8,521,487 | | |
Transaction price | |
(a)
Probability of events | |
N/A |
Milestone Interest | |
$ | 0 | | |
Probability adjusted
value | |
Probability of events
Timing of events | |
90.00%-100.00% (N/A)
1.25-12.25 years (N/A) |
| |
$ | 8,521,487 | | |
| |
| |
|
(a) There is no quantitative information to provide as this
method of measure is investment specific.
Private Companies and Other Restricted
Securities
The Fund may invest in private companies
and other restricted securities if these securities would currently comprise 10% or less of Managed Assets. The value of these securities
represented 2% of the Fund’s Managed Assets at June 30, 2023.
At June 30, 2023, the Fund had commitments
of $1,012,296 relating to additional investments in two private companies.
The following table details the acquisition
date, cost, carrying value per unit, and value of the Fund’s private companies and other restricted securities at June 30, 2023.
The Fund on its own does not have the right to demand that such securities be registered.
Security (#) | |
Acquisition Date |
| |
Cost | | |
Carrying Value per Unit | | |
Value | |
Amolyt Pharma SAS Series C Cvt. Pfd | |
01/25/23 |
| |
$ | 1,608,363 | | |
$ | 2.34 | | |
$ | 1,604,065 | |
Aristea Therapeutics, Inc. Series B Cvt. Pfd | |
07/27/21 |
| |
| 1,600,004 | | |
| 5.51 | | |
| 1,600,004 | |
Endeavor Biomedicines, Inc. Series B Cvt. Pfd | |
01/21/22 |
| |
| 2,002,482 | | |
| 4.72 | | |
| 1,999,999 | |
Flamingo Therapeutics, Inc. Series A3 Cvt. Pfd | |
04/21/20, 10/28/20 |
| |
| 3,142,774 | | |
| 6.67 | | |
| 908,991 | |
Fusion Pharmaceuticals, Inc. Common | |
09/20/22 |
| |
| 0 | | |
| 4.21 | | |
| 15,538 | |
IO Light Holdings, Inc. Series A2 Cvt. Pfd | |
04/30/20, 05/17/21, 09/15/21 |
† | |
| 337,063 | | |
| 2.85 | | |
| 290,037 | |
Oculis Holding AG Common | |
03/06/23 |
| |
| 2,559,002 | | |
| 11.13 | | |
| 3,388,139 | |
Priothera Ltd. Series A Cvt. Pfd | |
10/07/20,10/19/21 |
| |
| 2,265,198 | | |
| 10.91 | | |
| 2,118,391 | |
Rainier Therapeutics Milestone Interest | |
09/28/21 |
| |
| 143,115 | | |
| 0.00 | | |
| 0 | |
| |
|
| |
$ | 13,658,001 | | |
| | | |
$ | 11,925,164 | |
(#) |
See Schedule of Investments and corresponding footnotes for more information on each issuer. |
† |
Interest received as part of a corporate action for a previously owned security. |
At-the-Market Offering
The Fund has a registration statement
on file with the SEC, initially effective on December 6, 2022, authorizing the Fund to issue shares through an At-the-Market Offering
(ATM) having an aggregate value of up to $150,000,000. The offering costs associated with the Fund’s ATM offering are approximately
$278,586 of which $7,478 were charged to paid-in-capital upon the issuance of associated shares.
On December 14, 2022, the Fund entered
into a distribution agreement with Foreside Fund Services, LLC (Foreside), pursuant to which the Fund may offer and sell up to $150,000,000
of shares from time to time, through Foreside as its agent, in transactions deemed to be at the market as defined in Rule 415 under the
Securities Act of 1933, as amended (the Offering). Under the Distribution Agreement, Foreside may enter into sub-placement agent agreements
with one or more selected dealers. Foreside has entered into a sub-placement agent agreement, dated December 14, 2022 (the Sub-Placement
Agent Agreement), with UBS Securities LLC (UBS) relating to the shares to be offered under the Distribution Agreement. During the period
ended on June 30, 2023, 274,984 shares were sold under this agreement for $3,950,593 (net of commissions to Foreside and UBS of $39,906).
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