TEKLA WORLD HEALTHCARE FUND

 

SCHEDULE OF INVESTMENTS

JUNE 30, 2023 (Unaudited)

 

Non-Convertible Notes - 16.5%  Principal
Amount
    Value 
France – 0.5%              
Sanofi, 3.63% due 06/19/28  $2,600,000   $2,502,268 
           
Ireland – 0.3%          
Endo Dac/Endo Finance LLC/Endo Finco, Inc., 9.50% due 07/31/27 (a)    516,000    30,960 
Endo Dac/Endo Finance LLC/Endo Finco, Inc., 6.00% due 06/30/28 (a)    789,000    39,450 
Mallinckrodt International Finance S.A., 10.00% due 06/15/29(a)     997,897    152,179 
Shire Acquisitions Investments Ireland DAC, 3.20% due 09/23/26   1,500,000    1,407,952 
         1,630,541 
United Kingdom – 1.0%          
AstraZeneca plc, 3.38% due 11/16/25   5,000,000    4,806,143 
           
United States – 14.7%          
Abbott Laboratories, 4.75% due 11/30/36   5,652,000    5,661,694 
AbbVie, Inc., 4.50% due 05/14/35   3,200,000    3,038,876 
AbbVie, Inc., 4.45% due 05/14/46   1,705,000    1,498,688 
Amgen, Inc., 3.63% due 05/22/24   2,000,000    1,965,036 
Amgen, Inc., 2.00% due 01/15/32   1,555,000    1,227,313 
Baxalta, Inc., 4.00% due 06/23/25   831,000    806,048 
Becton, Dickinson and Co., 3.73% due 12/15/24   328,000    318,383 
Bristol-Myers Squibb Co., 3.40% due 07/26/29   1,400,000    1,299,905 
CVS Health Corp., 1.88% due 02/28/31   2,448,000    1,942,811 
DH Europe Finance II Sarl, 3.25% due 11/15/39   985,000    799,390 
Elevance Health, Inc., 2.55% due 03/15/31   3,200,000    2,686,568 
EMD Finance LLC, 3.25% due 03/19/25 (a)     4,000,000    3,833,134 
GlaxoSmithKline Capital plc, 3.00% due 06/01/24   1,400,000    1,367,891 
GlaxoSmithKline Capital plc, 3.38% due 06/01/29   1,000,000    928,197 
HCA, Inc., 5.38% due 02/01/25   1,250,000    1,238,728 
HCA, Inc., 5.25% due 04/15/25   600,000    592,162 
IQVIA, Inc., 5.00% due 05/15/27 (a)     710,000    682,976 
Johnson & Johnson, 2.45% due 03/01/26   4,300,000    4,059,820 
Johnson & Johnson, 2.90% due 01/15/28   1,400,000    1,316,745 
Laboratory Corporation of America Holdings, 3.60% due 02/01/25   1,400,000    1,352,648 
Medtronic, Inc., 4.38% due 03/15/35   1,675,000    1,609,542 
Merck & Co., Inc., 2.75% due 02/10/25   1,463,000    1,407,707 
Novartis Capital Corp., 3.40% due 05/06/24   2,115,000    2,078,521 
Par Pharmaceutical, Inc., 7.50% due 04/01/27 (a)    193,000    142,633 
Pfizer, Inc., 3.45% due 03/15/29   5,300,000    4,986,630 
Pfizer, Inc., 4.00% due 12/15/36   1,800,000    1,676,203 
Senior Housing Properties Trust, 4.75% due 05/01/24   1,750,000    1,629,478 
Syneos Health, Inc., 3.63% due 01/15/29 (a)     2,300,000    2,248,434 
The Cigna Group, 3.50% due 06/15/24   2,785,000    2,728,126 
The Cigna Group, 2.38% due 03/15/31   3,200,000    2,685,467 
UnitedHealth Group, Inc., 3.88% due 12/15/28   2,560,000    2,451,429 
UnitedHealth Group, Inc., 4.20% due 05/15/32   6,060,000    5,782,822 
Zimmer Biomet Holdings, Inc., 4.25% due 08/15/35   5,000,000    4,316,807 
         70,360,812 
Total Non-Convertible Notes (Cost $86,601,884)        79,299,764 

 

THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.

 

 

 

 

Convertible Preferreds (Restricted) (b) (c) - 1.8%   Shares     Value 
France – 0.5%              
Amolyt Pharma SAS Series C   686,916   $1,604,065 
Flamingo Therapeutics, Inc. Series A3   136,337    908,991 
         2,513,056 
Ireland – 0.5%          
Priothera Ltd. Series A, 6.00%   194,134    2,118,391 
           
United States – 0.8%          
Aristea Therapeutics, Inc. Series B, 8.00%   290,187    1,600,004 
Endeavor Biomedicines, Inc. Series B, 8.00%   424,079    1,999,999 
IO Light Holdings, Inc. Series A2   101,839    290,037 
         3,890,040 
Total Convertible Preferreds (Cost $10,955,883)        8,521,487 
           
Common Stocks - 103.1%          
Australia – 1.5%          
CSL Ltd.   38,719    7,154,370 
           
Canada – 0.0%          
Fusion Pharmaceuticals, Inc. (c)   7,378    34,529 
Fusion Pharmaceuticals, Inc. (Restricted) (b) (c)   3,689    15,538 
         50,067 
China – 0.2%          
BeiGene Ltd. ADR (c)   4,114    733,526 
I-Mab ADR (c)   38,848    116,156 
         849,682 
Denmark – 4.4%          
MorphoSys AG ADR (c)   177,191    1,323,617 
Novo Nordisk A/S ADR   122,777    19,869,002 
         21,192,619 
France – 1.4%          
Sanofi ADR   123,454    6,654,170 
           
Germany – 1.5%          
Affimed N.V. (c)   10,000    5,982 
Bayer AG   131,684    7,280,956 
         7,286,938 
Ireland – 0.5%          
ICON plc (c)   6,534    1,634,807 
Perrigo Co. plc   15,882    539,194 
         2,174,001 
Israel – 0.1%          
Teva Pharmaceutical Industries Ltd. ADR (c)   90,281    679,816 
           
Japan – 1.8%          
Astellas Pharma, Inc.   44,419    661,537 
Daiichi Sankyo Co., Ltd.   54,075    1,705,127 
Eisai Co., Ltd.   6,830    460,272 
Hoya Corp.   9,682    1,145,709 
M3, Inc.   7,436    160,217 
Olympus Corp.   28,940    454,472 
Ono Pharmaceutical Co., Ltd.   11,330    204,622 
Otsuka Holdings Co., Ltd.   20,808    760,102 
Shionogi & Co., Ltd.   7,707    324,207 
Sysmex Corp.   3,715    252,361 

 

THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.

 

 

 

 

   Shares     Value 
Japan – continued          
Takeda Pharmaceuticals Co., Ltd.   9,600   $301,183 
Takeda Pharmaceuticals Co., Ltd. ADR (d)   105,073    1,650,697 
Terumo Corp.   17,288    546,574 
         8,627,080 
Netherlands – 1.0%          
argenx SE ADR (c)   6,255    2,437,761 
Koninklijke Philips N.V.   114,765    2,489,253 
         4,927,014 
Switzerland – 9.6%          
Lonza Group AG   12,711    7,575,049 
Novartis AG ADR   136,225    13,746,464 
Oculis Holding AG (Restricted) (b)   304,333    3,388,139 
Roche Holding AG ADR   562,829    21,500,068 
         46,209,720 
United Kingdom – 4.6%          
AstraZeneca plc ADR   226,704    16,225,205 
Smith & Nephew plc ADR (d)   181,710    5,860,148 
         22,085,353 
United States – 76.5%          
Abbott Laboratories (e)   130,365    14,212,392 
AbbVie, Inc. (e)   132,594    17,864,390 
Acadia Healthcare Co., Inc. (c)   25,973    2,068,490 
Amgen, Inc. (e)   64,224    14,259,012 
Ardelyx, Inc. (c) (d)   282,002    955,987 
Avantor, Inc. (c)   142,388    2,924,649 
Baxter International, Inc.   86,526    3,942,125 
Biogen, Inc. (c)   15,208    4,331,999 
Boston Scientific Corp. (c) (e)   172,145    9,311,323 
Bristol-Myers Squibb Co.   100,088    6,400,628 
Charles River Laboratories International, Inc. (c) (e)   21,364    4,491,781 
Community Health Systems, Inc. (c)   8,700    38,280 
Community Healthcare Trust, Inc.   14,900    491,998 
Danaher Corp.   37,903    9,096,720 
DexCom, Inc. (c) (e)   64,567    8,297,505 
Diversified Healthcare Trust REIT   63,841    143,642 
Edwards Lifesciences Corp. (c)   51,018    4,812,528 
Elevance Health, Inc.   28,373    12,605,840 
Eli Lilly & Co.   37,180    17,436,676 
Galera Therapeutics, Inc. (c)   161,709    504,532 
Gilead Sciences, Inc.   87,662    6,756,110 
Global Medical REIT, Inc.   143,229    1,307,681 
GSK plc ADR   41,852    1,491,605 
Guardant Health, Inc. (c)   53,333    1,909,321 
HCA Healthcare, Inc.   16,303    4,947,634 
Healthcare Realty Trust, Inc.   149,567    2,820,834 
Healthpeak Properties, Inc.   83,601    1,680,380 
Humana, Inc. (e)   9,425    4,214,200 
IDEXX Laboratories, Inc. (c)   15,748    7,909,118 
Illumina, Inc. (c) (e)   35,007    6,563,462 
Insulet Corp. (c)   10,283    2,965,000 
Intuitive Surgical, Inc. (c)   17,195    5,879,658 
IQVIA Holdings, Inc. (c) (e)   28,415    6,386,840 
Johnson & Johnson (e)   182,963    30,284,036 
LTC Properties, Inc.   46,903    1,548,737 
Mallinckrodt plc (c)   35,048    41,357 

 

THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.

 

 

 

 

   Shares     Value 
United States - continued          
McKesson Corp. (e)   10,401   $4,444,451 
Medical Properties Trust, Inc. (d)   145,186    1,344,422 
Medtronic plc (e)   79,482    7,002,364 
Merck & Co., Inc. (e)   189,992    21,923,177 
Moderna, Inc. (c)   14,416    1,751,544 
Molina Healthcare, Inc. (c) (e)   14,583    4,392,983 
National Health Investors, Inc.   4,442    232,850 
Omega Healthcare Investors, Inc.   71,075    2,181,292 
Pfizer, Inc. (e)   429,273    15,745,734 
Physicians Realty Trust   291,309    4,075,413 
R1 RCM, Inc. (c)   124,297    2,293,280 
Regeneron Pharmaceuticals, Inc. (c)   9,088    6,530,091 
ResMed, Inc.   10,104    2,207,724 
Sabra Health Care REIT, Inc.   90,781    1,068,492 
Stryker Corp.   16,321    4,979,374 
The Cigna Group (e)   21,036    5,902,702 
Thermo Fisher Scientific, Inc. (e)   24,289    12,672,786 
UnitedHealth Group, Inc.   55,428    26,640,914 
Universal Health Realty Income Trust   8,183    389,347 
Ventas, Inc.   66,681    3,152,011 
Veradigm, Inc. (c)   90,363    1,138,574 
Vertex Pharmaceuticals, Inc. (c)   12,833    4,516,061 
Welltower, Inc.   41,484    3,355,641 
West Pharmaceutical Services, Inc.   3,370    1,288,924 
Zimmer Biomet Holdings, Inc. (e)   23,986    3,492,362 
Zoetis, Inc.   29,308    5,047,131 
         368,666,114 
Total Common Stocks (Cost $482,502,401)        496,556,944 

 

   Principal
Amount
    
Short-Term Investments– 4.0%          
MUFG Bank Ltd. Commercial Paper, 5.00%, due 07/06/23  $5,000,000    4,996,528 
Repurchase Agreement, Fixed Income Clearing Corp., repurchase value $11,885,505, 1.52%, dated 06/30/23, due 07/03/23 (collateralized by U.S. Treasury Note 1.500%, due 01/31/27, market value $12,121,761)   11,884,000    11,884,000 
         16,880,528 

 

  

Shares

   Value 
State Street Institutional U.S. Government Money Market Fund, Institutional Class, 5.03% (f)    2,657,701    2,657,701 
Total Short-Term Investments (Cost $19,538,229)        19,538,229 

Total Investments Before Milestone Interest – 125.4% (Cost $599,598,397)

        603,916,424 

 

   Interests     
Milestone Interest (Restricted) (b) (c) – 0.0%           
Biotechnology – 0.0%                  
Rainier Therapeutics Milestone Interest   1    0 
Total Milestone Interest (Cost $143,115)        0 

 

  Number of
Contracts (100
shares each)/
Notional Amount
($)
    
Option Contracts Written – (0.1)%      
Call Option Contracts Written – (0.1)%        
Abbott Laboratories Aug23 115 Call  190/(2,185,000)   (14,820)
Abbott Laboratories Jul23 112 Call  193/(2,161,600)   (15,826)
AbbVie, Inc. Aug23 140 Call  129/(1,806,000)   (23,091)
AbbVie, Inc. Jul23 135 Call  131/(1,768,500)   (22,401)

 

THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.

 

 

 

 

    Number of
Contracts (100
shares each)/
Notional Amount
($)
  Value 
Amgen, Inc. Aug23 235 Call  94/(2,209,000)  $(17,954)
Amgen, Inc. Jul23 230 Call  94/(2,162,000)   (8,836)
Boston Scientific Corp. Aug23 57.5 Call  165/(948,750)   (6,435)
Charles River Laboratories International, Inc. Aug23 230 Call  20/(460,000)   (7,800)
DexCom, Inc. Aug23 140 Call  63/(882,000)   (17,010)
DexCom, Inc. Jul23 135 Call  63/(850,500)   (7,875)
Humana, Inc. Aug23 470 Call  13/(611,000)   (8,580)
Humana, Inc. Jul23 460 Call  13/(598,000)   (5,070)
Illumina, Inc. Aug23 200 Call  34/(680,000)   (22,440)
IQVIA Holdings, Inc. Aug23 230 Call  27/(621,000)   (17,388)
Johnson & Johnson Aug23 170 Call  179/(3,043,000)   (29,535)
Johnson & Johnson Jul23 165 Call  179/(2,953,500)   (51,731)
McKesson Corp. Aug23 440 Call  10/(440,000)   (9,000)
Medtronic plc Aug23 90 Call  62/(558,000)   (9,982)
Merck & Co., Inc. Aug23 120 Call  185/(2,220,000)   (28,490)
Merck & Co., Inc. Jul23 115 Call  187/(2,150,500)   (42,823)
Molina Healthcare, Inc. Aug23 310 Call  14/(434,000)   (12,950)
Pfizer, Inc. Aug23 37.5 Call  620/(2,325,000)   (44,020)
Pfizer, Inc. Jul23 37.5 Call  637/(2,388,750)   (21,021)
The Cigna Group Aug23 290 Call  30/(870,000)   (20,400)
The Cigna Group Jul23 290 Call  31/(899,000)   (6,045)
Thermo Fisher Scientific, Inc. Aug23 540 Call  30/(1,620,000)   (32,040)
Thermo Fisher Scientific, Inc. Jul23 530 Call  30/(1,590,000)   (20,220)
Zimmer Biomet Holdings, Inc. Aug23 155 Call  23/(356,500)   (3,680)
Total Option Contracts Written (Premiums received ($353,833))      (527,463)

Total Investments - 125.3% (Cost $599,387,679)

      603,388,961 
Other Liabilities in Excess of Assets - (25.3)%      (121,671,996)
Net Assets - 100%     $481,716,965 

 

The percentage shown for each investment category in the Schedule of Investments is based on net assets. 

(a)Security exempt from registration under Rule 144A of the Securities Act of 1933, as amended. These securities may be resold in transactions exempt from registration, normally to qualified institutional buyers.
(b)Security fair valued using significant unobservable inputs. See Investment Valuation and Fair Value Measurements.
(c)Non-income producing security.
(d)All or a portion of this security is on loan as of June 30, 2023.
(e)A portion of security is pledged as collateral for call options written.
(f)This security represents the investment of cash collateral received for securities lending and is a registered investment company advised by State Street Global Advisors. The rate shown is the annualized seven-day yield as of June 30, 2023.
  
ADRAmerican Depository Receipt

 

The following forward contracts were held as of June 30, 2023:

 

Description  Counterparty  Settlement
 Date
  Currency  Settlement
Value (in USD)
   Current
Value
   Unrealized
Gain/(Loss)
 
Contracts Sold:                             
Australian Dollar  Goldman Sachs Bank  07/31/23   4,572,304   AUD  $3,074,335   $3,048,091   $26,244 
British Pound  Goldman Sachs Bank  07/31/23   9,440,375   GBP   12,039,365    11,991,490    47,875 
Danish Krone  Goldman Sachs Bank  07/31/23   48,474,501   DKK   7,130,521    7,114,881    15,640 
Euro  Goldman Sachs Bank  07/31/23   11,686,116   EUR   12,797,945    12,768,099    29,846 
Israeli Sheqel  Goldman Sachs Bank  07/31/23   4,457,647   ILS   1,231,420    1,203,461    27,959 
Japanese Yen  Goldman Sachs Bank  07/31/23   523,322,125   JPY   3,665,985    3,640,975    25,010 
Swiss Franc  Goldman Sachs Bank  07/31/23   20,140,361   CHF   22,588,878    22,561,393    27,485 
                      $62,328,390   $200,059 

 

THE ACCOMPANYING NOTES ARE AN INTEGRAL PART OF THIS SCHEDULE OF INVESTMENTS.

 

 

 

 

Investment Valuation

 

Shares of publicly traded companies listed on national securities exchanges or trading in the over-the-counter market are typically valued at the last sale price, as of the close of trading, generally 4 p.m., Eastern Time. The Fund holds securities, currencies and other assets that are denominated in a foreign currency. The Fund will normally use the currency exchange rates as of 4:00 p.m. (Eastern Time) when valuing such assets. The Board of Trustees of the Fund (the Trustees) has established and approved fair valuation policies and procedures with respect to securities for which quoted prices may not be available or which do not reflect fair value. Convertible, corporate and government bonds are valued using a third-party pricing service. Convertible bonds are valued using this pricing service only on days when there is no sale reported. Puts and calls generally are valued at the close of regular trading on the securities or commodities exchange on which they are primarily traded. Options on securities generally are valued at their last sale price in the case of exchange traded options or, in the case of OTC-traded options, the average of the last sale price as obtained from two or more dealers unless there is only one dealer, in which case that dealer’s price is used. Forward foreign currency contracts are valued on the basis of the value of the underlying currencies at the prevailing forward exchange rates. Restricted securities of companies that are publicly traded are typically valued based on the closing market quote on the valuation date adjusted for the impact of the restriction as determined in good faith by Tekla Capital Management LLC (the Adviser) also using fair valuation policies and procedures approved by the Trustees described below. Short-term investments with a maturity of 60 days or less are generally valued at amortized cost, which approximates fair value.

 

Convertible preferred shares, warrants or convertible note interests in private companies, milestone interests and other restricted securities, as well as shares of publicly traded companies for which market quotations are not readily available, such as stocks for which trading has been halted or for which there are no current day sales, or which do not reflect fair value, are typically valued in good faith, based upon the recommendations made by the Adviser pursuant to fair valuation policies and procedures approved by the Trustees.

 

The Adviser has a Valuation Sub-Committee comprised of senior management which reports to the Valuation Committee of the Board at least quarterly. Each fair value determination is based on a consideration of relevant factors, including both observable and unobservable inputs. Observable and unobservable inputs may include (i) the existence of any contractual restrictions on the disposition of securities; (ii) information obtained from the company, which may include an analysis of the company’s financial statements products, intended markets or technologies; (iii) the price of the same or similar security negotiated at arm’s length in an issuer’s completed subsequent round of financing; (iv) the price and extent of public trading in similar securities of the issuer or of comparable companies; or (v) a probability and time value adjusted analysis of contractual terms. Where available and appropriate, multiple valuation methodologies are applied to confirm fair value. Significant unobservable inputs identified by the Adviser are often used in the fair value determination. A significant change in any of these inputs may result in a significant change in the fair value measurement. Due to the uncertainty inherent in the valuation process, such estimates of fair value may differ significantly from the values that would have been used had a ready market for the investments existed, and differences could be material. Additionally, changes in the market environment and other events that may occur over the life of the investments may cause the gains or losses ultimately realized on these investments to be different from the valuations used at the date of this schedule of investments.

 

Federal Income Tax Cost

 

At June 30, 2023, the cost of securities for Federal income tax purposes was $600,801,335. The net unrealized gain on securities held by the Fund was $2,587,626, including gross unrealized gain of $70,401,918 and gross unrealized loss of $67,814,292.

 

Securities Lending

 

The Fund may lend its securities to approved borrowers to earn additional income. The Fund receives cash collateral from the borrower and the initial collateral received by the Fund is required to have a value of at least 102% of the current value of the loaned securities traded on U.S. exchanges, and a value of at least 105% for all other securities. The Fund will invest its cash collateral in State Street Institutional U.S. Government Money Market Fund (SAHXX), which is registered with the Securities and Exchange Commission (SEC) as an investment company. SAHXX invests substantially all of its assets in the State Street U.S. Government Money Market Portfolio. The Fund will receive the benefit of any gains and bear any losses generated by SAHXX with respect to the cash collateral.

 

 

 

 

The Fund has the right to recall loaned securities on demand. If a borrower fails to return loaned securities when due, then the lending agent is responsible and indemnifies the Fund for the lent securities. The lending agent uses the collateral received from the borrower to purchase replacement securities of the same issue, type, class and series of the loaned securities. If the value of the collateral is less than the purchase cost of replacement securities, the lending agent is responsible for satisfying the shortfall but only to the extent that the shortfall is not due to any decrease in the value of SAHXX.

 

Although the risk of loss on securities lent is mitigated by receiving collateral from the borrower and through lending agent indemnification, the Fund could experience a delay in recovering securities or could experience a lower than expected return if the borrower fails to return the securities on a timely basis. The Fund receives compensation for lending its securities by retaining a portion of the return on the investment of the collateral and compensation from fees earned from borrowers of the securities. Securities lending income received by the Fund is net of fees retained by the securities lending agent. Net income received from SAHXX is a component of securities lending income as recorded by the Fund.

 

As of June 30, 2023, the Fund loaned securities valued at $2,609,145 and received $2,657,701 of cash collateral.

 

Forward Contracts

 

Forward contracts involve the purchase or sale of a specific quantity of a commodity, government security, foreign currency, or other asset at a specified price, with delivery and settlement at a specified future date. Because it is a completed contract, a purchase forward contract can be a cover for the sale of a futures contract. The Fund may enter into forward contracts for hedging purposes and non-hedging purposes (i.e., to increase returns). Forward contracts may be used by the Fund for hedging purposes to protect against uncertainty in the level of future foreign currency exchange rates, such as when the Fund anticipates purchasing or selling a foreign security. Forward contracts may also be used to attempt to protect the value of the Fund’s existing holdings of foreign securities. Forward contracts may also be used for non-hedging purposes to pursue the Fund’s investment objective. There is no requirement that the Fund hedge all or any portion of its exposure to foreign currency risks.

 

Fair Value Measurements

 

The Fund uses a three-tier hierarchy to prioritize the assumptions, referred to as inputs, used in valuation techniques to measure fair value. The three-tier hierarchy of inputs is summarized in the three broad levels. Level 1 includes quoted prices in active markets for identical investments. Level 2 includes prices determined using other significant observable inputs (including quoted prices for similar investments, interest rates, credit risk, etc.). The independent pricing vendor may value bank loans and debt securities at an evaluated bid price by employing methodologies that utilize actual market transactions, broker-supplied valuations, and/or other methodologies designed to identify the market value for such securities and such securities are considered Level 2 in the fair value hierarchy. Level 3 includes prices determined using significant unobservable inputs (including the Fund’s own assumptions in determining the fair value of investments). These inputs or methodology used for valuing securities are not necessarily an indication of the risk associated with investing in those securities.

 

 

 

 

For the period ended June 30, 2023, there were no transfers between levels.

 

The following is a summary of the levels used as of June 30, 2023 to value the Fund’s investments.

 

Assets at Value  Level 1   Level 2   Level 3   Total 
Non-convertible Notes                    
France  $-   $2,502,268   $-   $2,502,268 
Ireland   -    1,630,541    -    1,630,541 
United Kingdom   -    4,806,143    -    4,806,143 
United States   -    70,360,812    -    70,360,812 
Convertible Preferreds                    
France   -    -    2,513,056    2,513,056 
Ireland   -    -    2,118,391    2,118,391 
United States   -    -    3,890,040    3,890,040 
Common Stocks                    
Australia   7,154,370    -    -    7,154,370 
Canada   34,529    15,538    -    50,067 
China   849,682    -    -    849,682 
Denmark   21,192,619    -    -    21,192,619 
France   6,654,170    -    -    6,654,170 
Germany   7,286,938    -    -    7,286,938 
Ireland   2,174,001    -    -    2,174,001 
Israel   679,816    -    -    679,816 
Japan   8,627,080    -    -    8,627,080 
Netherlands   4,927,014    -    -    4,927,014 
Switzerland   42,821,581    3,388,139    -    46,209,720 
United Kingdom   22,085,353    -    -    22,085,353 
United States   368,666,114    -    -    368,666,114 
Short-term Investments   2,657,701    16,880,528    -    19,538,229 
Milestone Interest                    
United States                                                                             -    -    0*   0*
Total  $495,810,968   $99,583,969   $8,521,487   $603,916,424 
Assets                    
Forward Currency Contracts  $-   $200,059   $-   $200,059 
Liabilities                    
Options Contracts Written   (527,463)   -    -    (527,463)
Total  $(527,463)  $200,059   $-   $(327,404)

 

* Represents security valued at zero.

 

The following is a reconciliation of Level 3 assets for which significant unobservable inputs were used to determine fair value.

 

Investments in Securities  Balance as of
September 30,
2022
  

Net realized

gain (loss) and

change in
unrealized
appreciation

(depreciation)

  

Cost of

purchases

and

conversions

  

Proceeds

from sales

and

conversions

  

Net

transfers

into

(out of)

Level 3

   Balance as
of June 30,
2023
 
Convertible Preferreds                              
France  $960,713   $(56,152)  $1,608,495   $   $   $2,513,056 
Ireland   1,902,611    215,780                2,118,391 
Switzerland   2,047,583    (336,172)       (1,711,411)        
United States   3,943,709    (53,851)   182            3,890,040 
Milestone Interest                              
United States   138,520    (138,520)               0*
Total  $8,993,136   $(368,915)  $1,608,677   $(1,711,411)  $   $8,521,487 
                               
Net change in unrealized appreciation (depreciation) from investments still held as of June 30, 2023        $(32,743) 

 

* Represents security valued at zero.

 

 

 

 

The following is a quantitative disclosure about significant unobservable inputs used in the determination of the fair value of Level 3 assets.

 

   Fair Value
at  June 30,
2023
  

Valuation

Technique

 

Unobservable

Input

 

Range

(Weighted Average)

Convertible Preferreds  $8,521,487   Transaction price 

(a)

Probability of events

  N/A
Milestone Interest  $0   Probability adjusted
value
  Probability of events
Timing of events
  90.00%-100.00% (N/A)
1.25-12.25 years (N/A)
   $8,521,487          

 

(a) There is no quantitative information to provide as this method of measure is investment specific.

 

Private Companies and Other Restricted Securities

 

The Fund may invest in private companies and other restricted securities if these securities would currently comprise 10% or less of Managed Assets. The value of these securities represented 2% of the Fund’s Managed Assets at June 30, 2023.

 

At June 30, 2023, the Fund had commitments of $1,012,296 relating to additional investments in two private companies.

 

The following table details the acquisition date, cost, carrying value per unit, and value of the Fund’s private companies and other restricted securities at June 30, 2023. The Fund on its own does not have the right to demand that such securities be registered.

 

Security (#)  Acquisition
Date
   Cost   Carrying Value
per Unit
   Value 
Amolyt Pharma SAS Series C Cvt. Pfd  01/25/23    $1,608,363   $2.34   $1,604,065 
Aristea Therapeutics, Inc. Series B Cvt. Pfd  07/27/21     1,600,004    5.51    1,600,004 
Endeavor Biomedicines, Inc. Series B Cvt. Pfd  01/21/22     2,002,482    4.72    1,999,999 
Flamingo Therapeutics, Inc. Series A3 Cvt. Pfd  04/21/20, 10/28/20     3,142,774    6.67    908,991 
Fusion Pharmaceuticals, Inc. Common  09/20/22     0    4.21    15,538 
IO Light Holdings, Inc. Series A2 Cvt. Pfd  04/30/20, 05/17/21, 09/15/21    337,063    2.85    290,037 
Oculis Holding AG Common  03/06/23     2,559,002    11.13    3,388,139 
Priothera Ltd. Series A Cvt. Pfd  10/07/20,10/19/21     2,265,198    10.91    2,118,391 
Rainier Therapeutics Milestone Interest  09/28/21     143,115    0.00    0 
        $13,658,001        $11,925,164 

 

(#) See Schedule of Investments and corresponding footnotes for more information on each issuer.
Interest received as part of a corporate action for a previously owned security.

 

At-the-Market Offering

 

The Fund has a registration statement on file with the SEC, initially effective on December 6, 2022, authorizing the Fund to issue shares through an At-the-Market Offering (ATM) having an aggregate value of up to $150,000,000. The offering costs associated with the Fund’s ATM offering are approximately $278,586 of which $7,478 were charged to paid-in-capital upon the issuance of associated shares.

 

On December 14, 2022, the Fund entered into a distribution agreement with Foreside Fund Services, LLC (Foreside), pursuant to which the Fund may offer and sell up to $150,000,000 of shares from time to time, through Foreside as its agent, in transactions deemed to be at the market as defined in Rule 415 under the Securities Act of 1933, as amended (the Offering). Under the Distribution Agreement, Foreside may enter into sub-placement agent agreements with one or more selected dealers. Foreside has entered into a sub-placement agent agreement, dated December 14, 2022 (the Sub-Placement Agent Agreement), with UBS Securities LLC (UBS) relating to the shares to be offered under the Distribution Agreement. During the period ended on June 30, 2023, 274,984 shares were sold under this agreement for $3,950,593 (net of commissions to Foreside and UBS of $39,906).

 

 

 


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