By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- European stock markets slipped from multiyear highs in downbeat action on Wednesday, as investors stayed cautious ahead of comments from the U.S. Federal Reserve Chairman Ben Bernanke.

The Stoxx Europe 600 index lost 0.2% to 309.26, retreating from the highest closing level since June 2008, reached on Tuesday.

Among biggest decliners, shares of Kazakhmys PLC dropped 4.8%, after UBS cut the miner to neutral from buy.

On a more upbeat note, shares of Britvic PLC surged 8.4%, after the beverage firm said adjusted earnings per share rose 48% for the 28 weeks to April 14, while increasing dividends 1.9% to 5.4 pence (82 cents).

For the broader European stock markets, most investors were hesitant to make any major moves, ahead of events in the U.S. that could provide some clarity on how and when the Fed chooses to fade out its $85-billion-a-month bond-purchase program. At 3 p.m. London time, 10 a.m. Eastern, Bernanke testifies before the Joint Economic Committee of Congress, his first testimony there since late February.

After the European market close the central bank releases the minutes from its April 30-May 1 meeting, hoping to provide some more insight in the Fed's stance on quantitative easing.

Back in Europe, minutes from the Bank of England's latest policy meeting are on tap in midmorning trade.

The U.K.'s FTSE 100 index traded 0.3% lower at 6,785.82, dropping after climbing to the highest closing level since December 1999 on Tuesday.

Germany's DAX 30 index dropped 0.1% to 8,462.02, on track to break an 11-day winning streak and retreat from an all-time high.

France's CAC 40 index slipped 0.1% to 4,033.52. Shares of Lagardere SCA added 2.5%, after J.P. Morgan Cazenove lifted the stock to neutral from underweight.

Outside the major indexes, shares of Roche Holding AG gained 1.4%, after Citigroup lifted the drug maker to buy from neutral.

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