(Adds background about Cook and Wilson.)

 
   DOW JONES NEWSWIRES 
 

Amylin Pharmaceuticals Inc. (AMLN) said Chairman Joseph C. Cook Jr. and lead director James N. Wilson were not re-elected to the board as two candidates nominated by large shareholders Eastbourne Capital Management LLC and billionaire investor Carl Icahn won seats.

Amylin said Tuesday, after the drug maker's annual meeting, that based on preliminary results no more than two dissidents had won seats. No further details were released at the time.

The winners were Kathleen Behrens, nominated by Eastbourne, and Icahn candidate Alexander J. Denner.

Cook was criticized by Howard Greene, Amylin's co-founder and former chief executive, who resigned from the board after he was not included in the company's slate of directors for re-election. Greene opposed Cook's re-election, saying he "has presided over the loss of shareholder value that sparked the proxy fight" with Eastbourne and Icahn.

Icahn also previously urged Cook, a former Amylin chief executive, to resign as chairman.

Wilson was active in criticizing Icahn for suggesting Amylin be sold to drug partner Eli Lilly & Co. (LLY). Wilson had said he and Cook thought a sale "today would dramatically undervalue the opportunity shareholders will have through the approval and launch of exenatide once weekly."

Icahn has protested the steep drop in Amylin's share price that began when news of patient deaths led the Food and Drug Administration to start working with Amylin and Lilly to add stronger warnings about severe pancreatitis to the label of diabetes drug Byetta.

Amylin had argued its board candidates were better suited to exploit the potential of its proposed diabetes drug Exenatide LAR, a new version of Byetta that would be taken once a week rather than injected twice a day. Approval is being sought from the FDA for Exenatide LAR, a potential blockbuster drug.

Icahn and Eastbourne, working separately, each nominated five directors for Amylin's 12-member board earlier this year. Then, fears that gaining a majority of the board would trigger a "poison put" on some of the company's debt led both groups to support three of Eastbourne's nominees and two of Icahn's.

The dissidents got strong support from well-known proxy-advisory firms, which hold a major influence on shareholders.

Amylin's shares recently traded up 2 cents at $11.28. The stock is down two-thirds since peaking in August.

-By Kathy Shwiff, Dow Jones Newswires; 201-938-5975; Kathy.Shwiff@dowjones.com

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