via NEWMEDIAWIRE – CFN Media Group (“CFN Media”), the leading
agency and financial media network dedicated to the North American
cannabis industry, announces publication of an interview
with Pascal Biosciences Inc. (TSX-V: PAS) President &
CEO Dr. Patrick W. Gray to discuss how the company is harnessing
the power of cannabis to develop cancer therapeutics.
The cannabis industry is projected to reach $75 billion by 2030,
according to Cowen & Co., driven by the legalization of
medical and recreational cannabis across a growing number of
states. While many investors are familiar with cultivators and
dispensaries, there could be an even greater opportunity on the
medical side of the industry. Cannabinoids could displace
blockbuster drugs, such as opioids, and provide breakthroughs in
other areas.
CFN Media: Your company hasn’t always been focused on
cannabis. What led you to take a closer look at cannabis and
discover the molecules that stimulate the immune system to destroy
cancer cells?
Dr. Patrick W. Gray: “Our work at Pascal
began with our sponsored research at the University of British
Columbia. We have a proprietary method to search for compounds that
can enhance the immune system, and a cannabinoid had the greatest
activity. We have since analyzed nearly 400 cannabinoids--natural,
synthetic, and endogenous---and we’ve identified even more potent
structures that are currently being tested in preclinical
immune-oncology studies. These discoveries about the anti-cancer
effects of cannabinoids are novel and fit with Pascal’s goal to
develop therapeutics for cancer.”
CFN Media: You recently announced the addition of a new
cannabinoid program for the treatment of Glioblastoma. How does
this program tie in to your immune surveillance program?
Dr. Patrick W. Gray: “I have known the
inventor of this technology, Dr. Nephi Stella, for nearly ten
years, and followed his work closely. When I saw his impressive
results in a glioblastoma animal model, I was convinced this is a
great program for Pascal. Glioblastoma is a terrible form of brain
cancer, and I believe Dr. Stella’s cannabinoid-based product has
great potential in treating this devastating disease. Furthermore,
Dr. Stella will be a consultant for Pascal, and his 20 years of
experience with cannabinoids will greatly aid our immune
surveillance program. Dr. Stella has done pioneering research with
cannabinoids, and he will bring that expertise to our
programs.”
CFN Media: Is Pascal considering any partnerships for your
cannabinoid programs?
Dr. Patrick W. Gray: “As you mentioned,
there is great medical potential for cannabinoids, with a clear
benefit for patients with pain, nausea, muscle spasms, epilepsy,
and anxiety. However, most clinical studies are suggestive at best,
and specific cannabinoids have generally not been associated with
patient benefit. Our work is focused on identifying specific
cannabinoids with potency for certain ailments. We believe our work
will be of significant interest to potential partners, including
both cannabis companies and pharmaceutical companies. The value of
our programs will continue to increase as we progress, and we
intend to engage potential partners when significant value is
attained.”
CFN Media: You recently secured a DEA Schedule I license
for cannabinoid development. Can you describe the process of
securing that license and why it’s significant?
Dr. Patrick W. Gray: “Obtaining a DEA
Schedule I license for Research was a critical step in further
developing our immune surveillance program using cannabinoids. The
process is quite rigorous. Yet, since we received our license, we
have screened nearly 400 cannabis derived compounds, many of which
are restricted, and have made significant progress in identifying
therapeutic candidates.”
CFN Media: What are some of the key upcoming catalysts that
shareholders can look forward to? Where do your clinical programs
stand at this point in time?
Dr. Patrick W. Gray: “Our
cannabinoid-based program for glioblastoma is expected to begin
human clinical trials in 2019, a significant milestone for the
company. In addition, our immune surveillance program is
progressing nicely with some exciting discoveries. We will report
our advancements in the scientific literature, at international
conferences, and in press releases. Investors can expect updates on
our programs in a timely fashion, because we have a lot of exciting
information to share!”
CFN Media: Why should investors consider your stock?
Dr. Patrick W. Gray: “Pascal has an
exciting pipeline developing cannabinoid therapeutics for cancer.
Cannabinoid-based medicines are a fast-growing opportunity given
the legalization of cannabis in Canada. The current competitive
landscape for biotechnology companies developing cannabinoid
therapeutics is small with diverse indications. Pascal stands out
as one of the few companies targeting glioblastoma and, more
broadly, cancer in combination with checkpoint inhibitors. Our
utmost priority is to help patients suffering from life-threatening
diseases, and we strongly believe that our current portfolio can
make an impact on patient lives.”
CFN Media: Thank you for taking the time to speak with
us.
About Pascal Biosciences Inc.
Pascal Biosciences Inc. (TSX-V:PAS) is a biotechnology
company focused on advancing innovative approaches for the
treatment of cancer including cannabinoid-based therapeutics and
targeted therapies. The company’s leading cannabinoid portfolio
comprises a small molecule therapeutic, ST-403, that is advancing
into clinical trials for the treatment of glioblastoma, and an
immuno-stimulatory molecule. In addition, Pascal Biosciences is
developing a B-cell targeted antibody for acute lymphoblastic
leukemia and an antibody for calcium channels expressed by the
immune system. For more information,
visit www.pascalbiosciences.com.
To learn more,
visit: https://www.pascalbiosciences.com/.
Please follow the link to read the full
article: http://www.cannabisfn.com/cfn-medias-exclusive-interview-pascal-biosciences/
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