SINGAPORE--Singapore's state-investment firm Temasek Holdings Pte. Ltd. said Thursday its net profit in the year ended March 31 fell 16% due to lower contributions from investments and its portfolio companies amid sluggish global growth, and flagged concerns over spillover impact from tepid U.S. and European economies.

Net profit for the fiscal year fell to 10.7 billion Singapore dollars (US$8.4 billion) from S$12.7 billion in the previous year.

"Asia's long-term growth potential remains healthy, though there will be structural and policy risks along the way, especially in the medium term," Temasek Chairman S. Dhanabalan said in a statement. "In the near term, Europe and the U.S. present significant risks, as well as potential opportunities."

The state investor has a net cash position, which it will maintain in order to take any investment opportunities that may arise, Mr. Dhanabalan added.

Temasek owns controlling stakes in some of Singapore's biggest corporations, including Singapore Airlines Ltd. (C6L.SG), shipping company Neptune Orient Lines Ltd. (N03.SG) and flagship telco Singapore Telecommunications Ltd. (Z74.SG). Rising costs and weaker worldwide demand weighed on the performance of some of these companies over the 12 months to March 31.

Temasek--the world's ninth-largest state investor according to the Sovereign Wealth Fund Institute--has in recent years sought to shift its investment focus toward emerging markets away from its home Singapore market and mature-market financial services. The firm has also expanded its China portfolio and steadily built investments in energy and resources.

In the year ended March 31, Temasek spent S$22 billion on new investments. The energy and resources sector was a major focus for the company, having invested S$2 billion investment in U.S. shale energy firm FTS International and with a S$1.3 billion investment in U.S. fertilizer producer Mosaic Co. (MOS), among others.

After a recent rebalancing of its investment in the Hong Kong-listed shares of several Chinese banks, Temasek now holds a 5.3% stake in Industrial and Commercial Bank of China Ltd. (1398.HK), a 7.4% stake in China Construction Bank Corp. (0939.HK) and a 3.7% stake in Bank of China Ltd. (3988.HK).

Temasek said it made divestments of S$15 billion, including in Indonesia's Chandra Asri Petrochemical (TPIA.JK), Singapore-listed Hutchison Port Holdings Trust (NS8U.SG), India's ICICI Bank Ltd. (532174.BY) and Kaisa Group Holdings Ltd. (1638.HK)

"We have a resilient portfolio that will continue to deliver steadily over the long term," Temasek Chief Executive Ho Ching said in the statement. "Over the next few years, we will continue to maintain a relaxed watchfulness."

Write to Chun Han Wong at chunhan.wong@dowjones.com and Martin Vaughan at martin.vaughan@dowjones.com