GNOW American CareSource Holdings Inc (CE)

American CareSource Holdings, Inc. (NASDAQ: ANCI) announced today that it has implemented a new client service agreement with the Principal Financial Group. Under the terms of the agreement, American CareSource will make available its full complement of ancillary care services to Principal Edge Network, a proprietary health care network launched in the Dallas-Ft. Worth metro area on March 1, 2009.

"We are very excited about the potential opportunities this partnership will create for our Company," stated David S. Boone, Chief Executive Officer of American CareSource. "As a provider of ancillary care services to the Principal Edge Network, we look forward to supporting their initial rollout in Texas and in other markets later this year. We feel that the agreement is a good fit between our companies as we both strive to deliver high quality services at cost effective prices."

"We're introducing Principal Edge Network to select markets where we believe our local presence will help employers achieve competitive discounts," said David McNichols, Vice President of the Health Division of the Principal Financial Group. "Our relationship with American CareSource is important to the success of ensuring our members have access to high quality ancillary care in their local markets."

About Ancillary Healthcare Services

American CareSource provides ancillary health care services through its network that offers cost effective alternatives to physician and hospital-based services. This market is estimated at $574 billion, and has grown to 30% of total national health expenditures. These providers offer services in over 30 categories, including laboratories, dialysis centers, free-standing diagnostic imaging centers, non-hospital surgery centers, as well as durable medical equipment such as orthotics and prosthetics, and others.

About American CareSource Holdings, Inc.

American CareSource Holdings, the first national, publicly traded ancillary care network services company, offers a comprehensive national network of approximately 2,500 ancillary service providers at over 25,000 sites through its subsidiary, Ancillary Care Services. The Company's ancillary network and management provides a complete outsourced solution for a wide variety of healthcare payors and plan sponsors including self-insured employers, indemnity insurers, PPOs, HMOs, third party administrators and both federal and local governments. For additional information, please visit www.anci-care.com.

About Principal Financial Group

The Principal Financial Group� (The Principal�)(1) is a leader in offering businesses, individuals and institutional clients a wide range of financial products and services, including retirement and investment services, life and health insurance, and banking through its diverse family of financial services companies. A member of the Fortune 500, the Principal Financial Group has $247.0 billion in assets under management(2) and serves some 19.1 million customers worldwide from offices in Asia, Australia, Europe, Latin America and the United States. Principal Financial Group, Inc. is traded on the New York Stock Exchange under the ticker symbol PFG. For more information, visit www.principal.com.

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Safe Harbor Statement Under the Private Securities Litigation Reform Act of 1995:

Any statements that are not historical facts contained in this release are forward-looking statements. It is possible that the assumptions made by American CareSource Holdings, Inc. for purposes of such statements may not materialize. Actual results may differ materially from those projected or implied in any forward-looking statements. Such statements may involve further risks and uncertainties, including but not limited to those relating to product demand, pricing, market acceptance, the effect of economic conditions, and intellectual property rights, and the outcome of competitive products, risks in product development, the ability to complete transactions, and other risks identified in this release, and the Securities and Exchange Commission filings of American CareSource Holdings, Inc.

(1) "The Principal Financial Group" and "The Principal" are registered service marks of Principal Financial Services, Inc., a member of the Principal Financial Group.

(2) As of December 31, 2008.

Contact: Steven J. Armond Chief Financial Officer American CareSource Holdings, Inc. Tel: 972-308-6847