VANCOUVER, July 28 /PRNewswire-FirstCall/ -- Angiotech Pharmaceuticals, Inc. (NASDAQ:ANPINASDAQ:TSX:NASDAQ:ANP), a global specialty pharmaceutical and medical device company, today announced its financial results for the second quarter ended June 30, 2008. "Our operating businesses continued to deliver results in the second quarter, with our Medical Products segment sales exceeding $50 million," said Dr. William Hunter, President and CEO of Angiotech. "Our various promoted brands again exhibited strong sales performance in the quarter, and we believe that we can achieve our full year objectives for sales growth, margin improvement and new product introductions." Significant Recent Developments On July 7, 2008, we announced that our Board of Directors authorized a transaction to establish separate operating and royalty businesses. For further information, please refer to the preliminary proxy statement filed with the SEC on July 22, 2008, available at http://www.sec.gov/. Second Quarter Financial Highlights - Total revenue was $76.1 million. - Net product sales were $50.5 million. - Royalty revenue was $25.5 million. - Adjusted EBITDA (earnings before interest, taxes, depreciation and amortization, adjusted to exclude certain non-cash and non-recurring items) was $5.9 million. - GAAP net loss and net loss per share from continuing operations were $26.1 million and $0.31, respectively. - Adjusted net loss from continuing operations and adjusted net loss per share from continuing operations (GAAP net loss as adjusted to exclude certain non-cash and non-recurring items) were $7.4 million and $0.09, respectively. - As of June 30, 2008, cash and cash equivalents and long-term investments were $81.0 million and net debt was $494.0 million. Second Quarter Business Highlights - Promoted Brand Strategy. Sales of our group of currently marketed promoted brand products continued to demonstrate higher revenue growth as compared to our overall product portfolio, consistent with the prior quarter. Revenue growth in our group of promoted brand products was approximately 54%, contributing to an aggregate growth rate of approximately 11% in total product revenue in the second quarter of 2008 as compared to the comparable quarter of 2007. During the second quarter, we launched our HemoStream(TM) chronic dialysis catheter in the U.S. as part of our promoted brands group, taking our total number of promoted brands available for sale to six, and we expect HemoStream to begin to contribute to sales of our Interventional business more significantly in the second half of 2008 and thereafter. - Base Medical Products Sales. Sales of products outside of our promoted brand product group also experienced growth during the quarter. Revenue growth in our base Surgical, Interventional and Specialties businesses (excluding promoted brands) was approximately 6% in the second quarter of 2008 as compared to the second quarter of 2007, reflecting the continued benefits of the realignment of our sales force completed at the end of 2007 and continued customer stability and growth in our Specialties business, which primarily sells medical devices and medical device components to other third party medical device makers. - Quill(TM) SRS. Adoption of our Quill Self Retaining System ("SRS") product line continued in the second quarter, consistent with the trends observed in the first quarter of 2008. On June 13, 2008, we announced the market launch of Monoderm, a new line of our Quill SRS product line made from a rapidly resorbing polymer, which is intended primarily for superficial wound closure applications. The product is now available for distribution and sale in the U.S. and Europe. - 5-FU Central Venous Catheter. On April 17, 2008 our 5-FU-eluting central venous catheter (CVC) product received 510(k) marketing clearance from the U.S. Food and Drug Administration (FDA). We currently expect to commercially launch our 5-FU CVC in the U.S. in the second half of 2008 under the brand name MicrobX. - Bio-Seal(TM) Lung Biopsy Tract System. On June 3, 2008, we announced the completion of our U.S. clinical trial enrolment for our novel Bio-Seal lung biopsy tract plug. Bio-Seal is a novel technology designed to reduce the incidence of post-operative pneumothorax (collapsed lung) in patients who undergo lung biopsy procedures. The primary endpoint of the Bio-Seal study is a reduction in the incidence of pneumothorax in patients undergoing lung biopsy procedures when compared with patients who do not receive the Bio- Seal product. The product has already received CE Mark approval and is available for commercial sale in Europe. - Zilver(R) PTX(TM) Paclitaxel-eluting Peripheral Stent. On June 11, 2008, our partner Cook Group Incorporated reported positive interim results from the registry arm of a clinical study designed to measure the efficacy of the Zilver PTX in treating peripheral arterial disease (PAD). The results were reported by trial investigators at the 2008 SVS Vascular Annual Meeting, and revealed clinical improvement, excellent durability and fracture resistance, high rates of event-free survival ("EFS") and freedom from target lesion revascularization ("TLR"). Interim data was compiled at six and 12 months using 435 patients and 200 patients, respectively. The corresponding EFS rates were 94 percent and 84 percent, and freedom from TLR was 96 percent and 88 percent. Evaluation of stent x-rays is ongoing, and currently suggests stent fractures in approximately one percent of cases at six months and less than two percent of cases at 12 months. In addition, the Zilver PTX stent exhibited no safety concerns and results were better than expected for TASC class C and D lesions, occlusions, in-stent restenosis and lesions greater than seven centimeters. Follow-up to the registry arm of the study is expected to continue through two years. Financial Information --------------------- This press release contains the condensed financial statements derived from the unaudited consolidated interim financial statements for the three- and six- month periods ended June 30, 2008, and 2007. Full unaudited consolidated interim financial statements and Management's Discussion and Analysis for the three- and six-month periods ended June 30, 2008, will be filed with the relevant regulatory agencies, as well as posted on our website at http://www.angiotech.com/. Amounts, unless specified otherwise, are expressed in U.S. dollars. Financial results are reported under GAAP unless otherwise noted. All per share amounts are stated on a diluted basis unless otherwise noted. Use of Certain Non-GAAP Financial Measures ------------------------------------------ Certain financial results presented in this press release include non-GAAP measures that exclude certain items. Adjusted net loss from continuing operations, adjusted net loss per share from continuing operations and adjusted earnings before interest, taxes, depreciation and amortization ("Adjusted EBITDA") exclude certain non-cash and non-recurring items such as acquisition related amortization charges, acquired in-process research and development relating to license agreements and acquisitions, stock-based compensation expense, foreign exchange gains or losses relating to translation of foreign currency cash and investment balances and other non-recurring items. Adjusted net loss from continuing operations, adjusted net loss per share from continuing operations and Adjusted EBITDA also exclude litigation expenses related to defending intellectual property claims. Revenue, as adjusted, excludes non-recurring, non-operating revenue derived from license agreements and other license revenue, net of license fees due to licensors and excludes amounts accrued for costs incurred. Adjusted net loss from continuing operations, adjusted net loss per share from continuing operations, revenue, as adjusted, and Adjusted EBITDA do not have any standardized meaning prescribed by GAAP and therefore may not be comparable to similar measures presented by other issuers. Management uses these non-GAAP or adjusted operating measures to establish operational goals, and believes that these measures may assist investors in analyzing the underlying trends in our business over time. Investors should consider these non-GAAP measures in addition to, not as a substitute for, or as superior to, financial reporting measures prepared in accordance with GAAP. We have provided a reconciliation of these measures to GAAP in the attached tables. The financial outlook referred to above presents certain forward-looking, non-GAAP financial information for which at this time there is no calculable comparable GAAP measure. As a result, such non-GAAP financial information cannot be quantitatively reconciled to comparable GAAP financial information. Specifically, the estimates for certain operating expenses referred to above exclude estimates of certain expenses that are inherently unpredictable or subject to significant fluctuation for reasons unrelated to our business performance, including stock-based compensation expenses, certain litigation expenses and foreign exchange gains or losses. Conference Call Information --------------------------- A conference call to discuss these financial results will be held today, Monday July 28, 2008 at 8:00 AM PT (11:00 AM ET). Dial-in information: North America (toll free): (800) 706-7745 International: (617) 614-3472 Enter passcode: 52264044 A replay archive of the conference call will be available until August 4, 2008 by calling (888) 286-8010 (in North America) or (617) 801-6888 (International) and entering passcode 85663575. A live webcast will be available to all interested parties through the Investors section of Angiotech's website: http://www.angiotech.com/ ANGIOTECH PHARMACEUTICALS, INC. CONDENSED CONSOLIDATED STATEMENTS OF INCOME (Unaudited) (in thousands of U.S.$, except share and per Three months ended Three months ended share data) 30-Jun-08 30-Jun-07 ------------------------------------------------------------------------- Adjust- Adjust- Reported ment Adjusted Reported ment Adjusted REVENUE Royalty revenue $ 25,536 $ - $ 25,536 $ 29,878 $ - $ 29,878 Product sales, net 50,533 - 50,533 42,421 2,980 a 45,401 License fees 53 (53)b - 53 (53)b - ------------------------------------------------------------------------- 76,122 (53) 76,069 72,352 2,927 75,279 ------------------------------------------------------------------------- EXPENSES License and royalty fees 3,661 - 3,661 4,268 - 4,268 Cost of products sold 26,809 (28)d 26,781 25,085 (927)c 24,158 Research and development 18,584 (1,366)e 17,218 13,458 (781)e 12,677 Selling, general and administra- tive 25,813 (2,167)f 23,646 24,363 (4,774)f 19,589 Depreciation and amort- ization 8,539 (7,593)g 946 8,328 (7,459)g 869 In-process research and development - - - 8,000 (8,000)h - ------------------------------------------------------------------------- 83,406 (11,154) 72,252 83,502 (21,941) 61,561 ------------------------------------------------------------------------- Operating (loss) income $ (7,284) $11,101 $ 3,817 $(11,150) $24,868 $ 13,718 ------------------------------------------------------------------------- Other income (expenses): Foreign exchange gain (loss) 140 (140)i - (505) 505 i - Investment and other income 686 12 j 698 (994) 1,933 j 939 Loss on sale/ write-down of investments (10,660) 10,660 k - - - - Interest expense on long-term debt (10,941) 559 l (10,382) (12,896) 568 l (12,328) ------------------------------------------------------------------------- (20,775) 11,09 1 (9,684) (14,395) 3,006 (11,389) ------------------------------------------------------------------------- (Loss) income from continuing operations before income taxes $(28,059) $22,192 $ (5,867) $(25,545) $ 27,874 $ 2,329 Income tax (recovery) expense (1,988) 3,563 m 1,575 (10,500) 7,857 m (2,643) ------------------------------------------------------------------------- (Loss) income from continuing operations (26,071) 18,629 (7,442) (15,045) 20,017 4,972 Net loss from discontinued operations, net of income taxes - - - (170) 170 - ------------------------------------------------------------------------- Net (loss) income for the period $(26,071) $18,629 $ (7,442) $(15,215) $ 20,187 $ 4,972 ------------------------------------------------------------------------- Basic and diluted net loss per common share from continuing operations $ (0.31) $ (0.09) $ (0.18) $ 0.06 ------------------------------------------------------------------------- ------------------------------------------------------------------------- Weighted average shares outstanding (000's) - basic and diluted 85,122 85,122 85,014 85,014 ------------------------------------------------------------------------- ------------------------------------------------------------------------- a. Amounts incurred for costs incurred, and potential future costs, related to our discontinuation of the Contour Threads brand product. b. Non-recurring, non-operating license revenue, net of license fees due to licensors. c. Change in estimate of accounting for excess and obsolete inventory resulting from the alignment during the second quarter of 2007 of inventory policies across our various manufacturing operations. d. Non-recurring supply/distribution agreement termination costs. e. Research and development adjustments: --------------------------------------------------------------------- Three months Three months ended ended Jun 30, 2008 Jun 30, 2007 ----------------------------------- Stock-based compensation $ (189) $ (531) Termination and reorganization costs (677) (250) Non-recurring supply/distribution agreement termination costs (500) - --------------------------------------------------------------------- $ (1,366) $ (781) ----------------------------------- f. Selling, general and administrative adjustments: --------------------------------------------------------------------- Three months Three months ended ended Jun 30, 2008 Jun 30, 2007 ----------------------------------- Stock-based compensation $ (418) $ (774) Termination and reorganization costs (1,026) (1,846) Litigation expenses relating to defending intellectual property claims (691) (2,154) Non-recurring supply/distribution agreement termination costs (32) - --------------------------------------------------------------------- $ (2,167) $ (4,774) ----------------------------------- g. Amortization of acquisition related intangible assets and medical technologies. h. Non-recurring in-process research and development expense relating to payments made to licensors and collaborators. i. Foreign exchange fluctuations on foreign currency net monetary assets. j. Write off of uncollectible tax receivable and write off of certain capitalized costs. k. Loss on write down of investments. l. Amortization of deferred financing costs. m. Tax effects of adjustments a. through l. for the period, including the reversal of tax reserves previously booked. ANGIOTECH PHARMACEUTICALS, INC. CONDENSED CONSOLIDATED STATEMENTS OF INCOME (Unaudited) (in thousands of U.S.$, except share and per Six months ended Six months ended share data) 30-Jun-08 30-Jun-07 ------------------------------------------------------------------------- Adjust- Adjust- Reported ment Adjusted Reported ment Adjusted REVENUE Royalty revenue $ 54,465 $ - $ 54,465 $ 62,878 $ - $ 62,878 Product sales, net 98,259 - 98,259 84,907 2,980 a 87,887 License fees 106 (106)b - 525 (525)b - ------------------------------------------------------------------------- 152,830 (106) 152,724 148,310 2,455 150,765 ------------------------------------------------------------------------- EXPENSES License and royalty fees 8,032 - 8,032 9,709 - 9,709 Cost of products sold 52,658 (28)c 52,630 47,877 (1,727)c 46,150 Research and development 34,889 (2,932)d 31,957 27,221 (3,890)d 23,331 Selling, general and administra- tive 53,654 (6,718)e 46,936 47,818 (10,021)e 37,797 Depreciation and amortization 17,017 (15,178)f 1,839 16,483 (14,734)f 1,749 In-process research and development 2,500 (2,500)g - 8,000 (8,000)g - ------------------------------------------------------------------------- 168,750 (27,356) 141,394 157,108 (38,372) 118,736 ------------------------------------------------------------------------- Operating (loss) income $(15,920) $27,250 $ 11,330 $ (8,798) $40,827 $ 32,029 ------------------------------------------------------------------------- Other income (expenses): Foreign exchange gain (loss) 563 (563)h - (403) 403 h - Investment and other income 1,442 12 i 1,454 7,808 (5,577)i 2,231 Loss on sale/ write-down of investments (10,660) 10,660 k - (8,157) 8,157 j - Interest expense on long-term debt (23,061) 1,118 l (21,943) (25,695) 1,126 l (24,569) ------------------------------------------------------------------------- (31,716) 11,227 (20,489) (26,447) 4,109 (22,338) ------------------------------------------------------------------------- (Loss) income from continuing operations before income taxes $(47,636) $38,477 $ (9,159) $(35,245) $44,936 $ 9,691 Income tax (recovery) expense (5,802) 7,961 m 2,159 (13,529) 10,301 m (3,228) ------------------------------------------------------------------------- (Loss) income from continuing operations (41,834) 30,516 (11,318) (21,716) 34,635 12,919 Net loss from discontinued operations, net of income taxes - - - (5,791) 5,791 - ------------------------------------------------------------------------- Net (loss) income for the period $(41,834) $30,516 $(11,318) $(27,507) $40,426 $ 12,919 ------------------------------------------------------------------------- Basic and diluted net (loss) income per common share from continuing operations $ (0.49) $ (0.13) $ (0.25) $ 0.15 ------------------------------------------------------------------------- ------------------------------------------------------------------------- Weighted average shares outstanding (000's) - basic and diluted 85,114 85,114 85,008 85,008 ------------------------------------------------------------------------- ------------------------------------------------------------------------- a. Amounts incurred for costs incurred, and potential future costs, related to our discontinuation of the Contour Threads brand product. b. Non-recurring, non-operating license revenue, net of license fees due to licensors. c. Change in estimate of accounting for excess and obsolete inventory resulting from the alignment during the second quarter of 2007 of inventory policies across our various manufacturing operations, and non-recurring supply/distribution agreement termination costs. d. Research and development adjustments: --------------------------------------------------------------------- Six months Six months ended ended Jun 30, 2008 Jun 30, 2007 ----------------------------------- Stock-based compensation $ (500) (973) License fees due to licensors related to non-recurring license revenue - (419) Termination and reorganization costs (1,307) (849) Non-recurring supply/distribution agreement termination costs (500) (899) Non-recurring in-process research and development expenses and intellectual property license agreement. (625) (750) --------------------------------------------------------------------- $ (2,932) $ (3,890) ----------------------------------- e. Selling, general and administrative adjustments: --------------------------------------------------------------------- Six months Six months ended ended Jun 30, 2008 Jun 30, 2007 ----------------------------------- Stock-based compensation $ (924) $ (1,392) Termination and reorganization costs (2,755) (3,385) Litigation expenses relating to defending intellectual property claims (2,289) (4,994) Non-recurring supply/distribution agreement termination costs (751) (250) --------------------------------------------------------------------- $ (6,718) $(10,021) ----------------------------------- f. Amortization of acquisition related intangible assets and medical technologies. g. Non-recurring in-process research and development expense. h. Foreign exchange fluctuations on foreign currency net monetary assets. i. Write off of uncollectible tax receivable and write off of certain capitalized costs. j. Net impact of loss and gain on redemption of investments of common share holdings in Orthovita Inc. and NuVasive Inc. respectively. k. Loss on write down of investments. l. Amortization of deferred financing costs. m. Tax effects of adjustments a. through l. for the period, including the reversal of tax reserves previously booked. ANGIOTECH PHARMACEUTICALS, INC. CALCULATION OF ADJUSTED EBITDA (Unaudited) Three months Six months ended June 30 ended June 30 (in thousands of U.S.$) 2008 2007 2008 2007 ------------------------------------------------------------------------- Net (loss) income on a GAAP basis $ (26,071) $ (15,215) $ (41,834) $ (26,096) Interest expense on long-term debt 10,941 12,896 23,061 25,695 Income tax expense (recovery) (1,988) (10,649) (5,802) (17,420) Depreciation and amortization 9,723 9,524 19,172 18,775 ------------------------------------------------------------------------- EBITDA $ (7,395) $ (3,444) $ (5,403) $ 954 ------------------------------------------------------------------------- Adjustments: Net loss from discontinued operations, excluding depreciation, amortization and income tax expense included above $ - $ 159 $ - $ 9,379 In-process research and development - 8,000 2,500 8,000 Non-recurring research and development - - 625 750 Non-recurring revenue, net of license fees (53) (53) (106) (106) Stock-based compensation 607 1,305 1,425 2,364 Litigation expenses 691 2,154 2,289 4,994 Foreign exchange gain (140) 505 (563) 403 Investment and other income (686) (939) (1,442) (2,231) Severance 1,762 1,846 4,840 3,984 Supply/distribution agreement termination costs - 250 - 2,199 E&O inventory adjustment - 927 - 927 Contour Threads return costs accrual - 2,980 - 2,980 Write off of capitalized costs 500 280 500 280 Write off uncollectible tax receivable - 2,250 - 2,250 Accrued interest income - (597) - (597) Writedown/loss on redemption of investments 10,660 - 10,660 647 ------------------------------------------------------------------------- Adjusted EBITDA $ 5,946 $ 15,623 $ 15,325 $ 37,177 ------------------------------------------------------------------------- ANGIOTECH PHARMACEUTICALS, INC. CONDENSED CONSOLIDATED BALANCE SHEETS (Unaudited) As at June 30, December 31, (in thousands of U.S.$) 2008 2007 ------------------------------------------------------------------------- ASSETS Cash and cash equivalents $ 62,915 $ 91,326 Accounts receivable 28,681 22,678 Inventories 36,240 33,647 Deferred income taxes 4,843 5,964 Other current assets 4,964 7,070 ------------------------------------------------------------------------- Total current assets $ 137,643 $ 160,685 ------------------------------------------------------------------------- Long-term investments $ 18,092 $ 24,456 Property and equipment, net 61,279 59,187 Intangible assets, net 213,158 225,889 Goodwill 667,624 659,511 Deferred income taxes 2,988 - Deferred financing costs 12,481 13,600 Other assets 8,921 6,780 ------------------------------------------------------------------------- Total assets $1,122,186 $1,150,108 ------------------------------------------------------------------------- ------------------------------------------------------------------------- LIABILITIES AND STOCKHOLDERS' EQUITY Current liabilities $ 63,630 $ 62,940 Long-term debt 575,000 575,000 Deferred income taxes 55,657 59,368 Other tax liabilities 5,534 4,693 Other long-term liabilities 5,701 6,035 Stockholders' equity 416,664 442,072 ------------------------------------------------------------------------- Total liabilities and stockholders' equity $1,122,186 $1,150,108 ------------------------------------------------------------------------- ------------------------------------------------------------------------- Forward-Looking Statements -------------------------- Statements contained in this press release that are not based on historical fact, including without limitation statements containing the words "believes," "may," "plans," "will," "estimate," "continue," "anticipates," "intends," "expects" and similar expressions, constitute "forward-looking statements" within the meaning of the U.S. Private Securities Litigation Reform Act of 1995 and constitute "forward-looking information" within the meaning of applicable Canadian securities laws. All such statements are made pursuant to the "safe harbor" provisions of applicable securities legislation. Forward-looking statements may involve, but are not limited to, comments with respect to our objectives and priorities for the second half of 2008 and beyond, and our strategies or future actions, our targets, expectations for our financial condition and the results of, or outlook for, our operations, research development and product and drug development. Such forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the actual results, events or developments to be materially different from any future results, events or developments expressed or implied by such forward-looking statements. Many such risks, uncertainties and other factors are taken into account as part of our assumptions underlying these forward-looking statements and include, among others, the following: general economic and business conditions, both nationally and in the regions in which we operate; market demand; technological changes that could impact our existing products or our ability to develop and commercialize future products; competition; existing governmental regulations and changes in, or the failure to comply with, governmental regulations; adverse results or unexpected delays in pre-clinical and clinical product development processes; adverse findings related to the safety and/or efficacy of our products or products sold by our partners; decisions, and the timing of decisions, made by health regulatory agencies regarding approval of our technology and products; the requirement for substantial funding to conduct research and development, to expand manufacturing and commercialization activities or consummate acquisitions; and any other factors that may affect performance. In addition, our business is subject to certain operating risks that may cause the actual results expressed or implied by the forward-looking statements in this press release to differ materially from our actual results. These operating risks include: our ability to attract and retain qualified personnel; our ability to successfully complete preclinical and clinical development of our products; changes in business strategy or development plans; our failure to obtain patent protection for discoveries; loss of patent protection resulting from third party challenges to our patents; commercialization limitations imposed by patents owned or controlled by third parties; our ability to obtain rights to technology from licensors; liability for patent claims and other claims asserted against us; our ability to obtain and enforce timely patent and other intellectual property protection for our technology and products; the ability to enter into, and to maintain, corporate alliances relating to the development and commercialization of our technology and products; market acceptance of our technology and products; our ability to successfully manufacture, market and sell our products; the continued availability of capital to finance our activities; our ability to continue to service our debt obligations; and any other factors referenced in our annual information form and other filings with the applicable Canadian securities regulatory authorities or the Securities and Exchange Commission. Given these uncertainties, assumptions and risk factors, readers are cautioned not to place undue reliance on such forward-looking statements. Except as required by law, we disclaim any obligation to update any such factors or to publicly announce the result of any revisions to any of the forward-looking statements contained in this press release to reflect future results, events or developments. Additional Information and Where to Find It ------------------------------------------- In connection with the proposed establishment of separate royalty and operating businesses, Angiotech filed a preliminary proxy statement with the SEC. The preliminary proxy statement is not yet final and will be amended. Shareholders are urged to read the final proxy statement (and all amendments and supplements to it) and other materials that Angiotech may file with the SEC when they become available in their entirety, because they contain important information about the proposed transaction. The final proxy statement will be mailed to Angiotech's shareholders. Shareholders will be able to obtain free copies of the final proxy statement, as well as Angiotech's other filings, without charge, at the SEC's Web site (http://www.sec.gov/) when they become available. Copies of the filings may also be obtained without charge from Angiotech by directing a request to: Angiotech Pharmaceuticals, Inc., 1618 Station Street, Vancouver, British Columbia, Canada V6A 1B6, Attention: Investor Relations (Tel: (604) 221-7676). Participants in the Solicitation -------------------------------- Angiotech and its directors, executive officers and other members of management and employees may be deemed to be participants in the solicitation of proxies from the holders of Angiotech common shares in respect of the proposed transaction. Information about the directors and executive officers is set forth in Angiotech's Annual Report on Form 40-F for the most recently ended fiscal year, which was filed with the SEC on March 31, 2008, and Angiotech's proxy statement for its 2008 annual and special general meeting of shareholders, filed with the SEC on July 22, 2008. Additional information regarding the interests of such potential participants will be included in the final proxy statement and the other relevant documents filed with the SEC when they become available. Quill(TM) is a trademark of Quill Medical, Inc., a wholly-owned subsidiary of Angiotech Pharmaceuticals, Inc. BioSeal(TM) is a trademark of Medical Device Technologies, Inc., a wholly-owned subsidiary of Angiotech Pharmaceuticals, Inc. Zilver(R) PTX(TM) is a trademark of Cook Group Incorporated. HemoStream(TM) is a trademark of Rex Medical, LP, used under license by Angiotech Pharmaceuticals, Inc. (C) 2008 Angiotech Pharmaceuticals, Inc. All Rights Reserved. About Angiotech Pharmaceuticals ------------------------------- Angiotech Pharmaceuticals, Inc. is a global specialty pharmaceutical and medical device company with over 1,500 dedicated employees. Angiotech discovers, develops and markets innovative treatment solutions for diseases or complications associated with medical device implants, surgical interventions and acute injury. To find out more about Angiotech (NASDAQ:ANPINASDAQ:TSX:NASDAQ:ANP) please visit our website at http://www.angiotech.com/. DATASOURCE: Angiotech Pharmaceuticals, Inc. CONTACT: Sage Baker, Investor Relations and Corporate Communications, Angiotech Pharmaceuticals, Inc., (604) 221-6933,

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