| T. Rowe Price Group, Inc. | Institution | 1.553.210 | 9,08% | US$ 18,90M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1.205.277 | 7,05% | US$ 14,67M | 2026-03-31 |
| RA Capital Healthcare Fund, L.P. | Institution | 864.102 | 5,05% | US$ 10,52M | 2026-03-31 |
| RA Capital Management, L.P. | Institution | 864.102 | 5,05% | US$ 10,52M | 2026-03-31 |
| Cantor Fitzgerald Asset Management | Institution | 813.648 | 4,76% | US$ 9,90M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 626.869 | 3,66% | US$ 7,63M | 2026-03-31 |
| TIG Advisors, LLC | Institution | 607.552 | 3,55% | US$ 7,39M | 2026-03-31 |
| Pentwater Capital Management LP | Institution | 602.649 | 3,52% | US$ 7,33M | 2026-03-31 |
| Sessa Capital IM, L.P. | Institution | 551.391 | 3,22% | US$ 6,71M | 2026-03-31 |
| Farallon Capital Management, L.L.C. | Institution | 349.360 | 2,04% | US$ 4,25M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 344.369 | 2,01% | US$ 4,19M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 319.831 | 1,87% | US$ 3,89M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 315.393 | 1,84% | US$ 3,84M | 2026-03-31 |
| 683 Capital Management, LLC | Institution | 300.000 | 1,75% | US$ 3,65M | 2026-03-31 |
| Ms. Sarah Boyce | Insider | 265.086 | 1,55% | US$ 3,23M | 2026-02-26 |
| Bellevue Asset Management AG | Institution | 263.096 | 1,54% | US$ 3,20M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 257.086 | 1,50% | US$ 3,13M | 2026-03-31 |
| Weiss Asset Management, LLC | Institution | 240.701 | 1,41% | US$ 2,93M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 235.115 | 1,37% | US$ 2,86M | 2026-03-31 |
| Squarepoint OPS LLC | Institution | 231.466 | 1,35% | US$ 2,82M | 2026-03-31 |
| Arbiter Partners Capital Management, LLC | Institution | 230.000 | 1,34% | US$ 2,80M | 2026-03-31 |
| Millennium Management LLC | Institution | 190.859 | 1,12% | US$ 2,32M | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 183.580 | 1,07% | US$ 2,23M | 2026-03-31 |
| Slotnik Capital, LLC | Institution | 180.945 | 1,06% | US$ 2,20M | 2026-03-31 |
| AQR Capital Management, LLC | Institution | 179.713 | 1,05% | US$ 2,19M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 178.560 | 1,04% | US$ 2,17M | 2026-03-31 |
| Schonfeld Strategic Advisors LLC | Institution | 162.759 | 0,95% | US$ 1,98M | 2026-03-31 |
| Marble Bar Asset Management LLP | Institution | 147.000 | 0,86% | US$ 1,79M | 2026-03-31 |
| Highland Capital Management, L.P. | Institution | 145.171 | 0,85% | US$ 1,77M | 2026-03-31 |
| Morgan Stanley | Institution | 143.025 | 0,84% | US$ 1,74M | 2026-03-31 |
| Janus Henderson Group plc | Institution | 139.973 | 0,82% | US$ 1,70M | 2026-03-31 |
| Bracebridge Capital, LLC | Institution | 139.239 | 0,81% | US$ 1,69M | 2026-03-31 |
| Nomura Holdings, Inc. | Institution | 137.380 | 0,80% | US$ 1,67M | 2026-03-31 |
| Bank of America Corporation | Institution | 136.248 | 0,80% | US$ 1,66M | 2026-03-31 |
| Yakira Capital Management, Inc. | Institution | 126.645 | 0,74% | US$ 1,54M | 2026-03-31 |
| Creek Drive Management Group LLC | Institution | 120.000 | 0,70% | US$ 1,46M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 116.598 | 0,68% | US$ 1,42M | 2026-03-31 |
| TD Asset Management, Inc. | Institution | 111.200 | 0,65% | US$ 1,35M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 109.936 | 0,64% | US$ 1,34M | 2026-03-31 |
| Athos Capital Limited | Institution | 107.965 | 0,63% | US$ 1,31M | 2026-03-31 |