| BlackRock, Inc. | Institution | 3.981.387 | 5,82% | US$ 4,82M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 2.855.966 | 4,18% | US$ 3,46M | 2026-03-31 |
| Laurion Capital Management LP | Institution | 2.646.738 | 3,87% | US$ 3,20M | 2026-03-31 |
| Pfizer Venture Investments LLC | Institution | 2.411.575 | 3,53% | US$ 2,92M | 2026-03-31 |
| Acorn Bioventures | Institution | 1.762.084 | 2,58% | US$ 2,13M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.599.663 | 2,34% | US$ 1,94M | 2026-03-31 |
| Dr. Gary Pace | Insider | 1.345.676 | 1,97% | US$ 1,63M | 2025-07-30 |
| Franklin Resources, Inc. | Institution | 1.205.803 | 1,76% | US$ 1,46M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.186.947 | 1,74% | US$ 1,44M | 2026-03-31 |
| William Blair Investment Management, LLC | Institution | 922.407 | 1,35% | US$ 1,12M | 2026-03-31 |
| F. L. Putnam Investment Management Co. | Institution | 595.127 | 0,87% | US$ 720,10k | 2026-03-31 |
| Northern Trust Global Investments | Institution | 493.205 | 0,72% | US$ 596,78k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 446.225 | 0,65% | US$ 539,93k | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 437.214 | 0,64% | US$ 529,03k | 2026-03-31 |
| UBS Asset Management AG | Institution | 400.576 | 0,59% | US$ 484,70k | 2026-03-31 |
| BNY Asset Management | Institution | 303.428 | 0,44% | US$ 367,15k | 2026-03-31 |
| XTX Markets Limited | Institution | 250.222 | 0,37% | US$ 302,77k | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 206.990 | 0,30% | US$ 250,46k | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 164.708 | 0,24% | US$ 199,30k | 2026-03-31 |
| Avestar Capital, LLC | Institution | 136.145 | 0,20% | US$ 164,74k | 2026-03-31 |
| Citadel Advisors LLC | Institution | 125.566 | 0,18% | US$ 151,93k | 2026-03-31 |
| GSA Capital Partners LLP | Institution | 123.008 | 0,18% | US$ 148,84k | 2026-03-31 |
| Ms. Lale White | Insider | 113.788 | 0,17% | US$ 137,68k | 2025-04-28 |
| AlphaCore Wealth Advisory, LLC | Institution | 108.426 | 0,16% | US$ 131,20k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 101.253 | 0,15% | US$ 122,52k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 92.359 | 0,14% | US$ 111,75k | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 84.626 | 0,12% | US$ 102,40k | 2026-03-31 |
| Teachers Insurance and Annuity Association-College Retirement Equities Fund | Institution | 75.661 | 0,11% | US$ 91,55k | 2026-03-31 |
| Rhumbline Advisers Ltd Partnership | Institution | 73.896 | 0,11% | US$ 89,41k | 2026-03-31 |
| Mr. James Levine | Insider | 67.716 | 0,10% | US$ 81,94k | 2025-04-28 |