OPRX OptimizeRx Corporation

OPTIMIZERx Corporation (OTCBB: OPRX) announces that on Monday, October 25th they have installed and launched their SampleMD solution within the Dreyer Medical Clinics. SampleMD staff trained all prescribing personnel that week at the 11 participating clinics that now have access to the voucher and co-pay programs made available through the SampleMD solution.

Additionally, OPTIMIZERx will be installing and launching the SampleMD solution within the Carilion Clinics during the week of November 8th and Emory Health System, the largest health care system in Georgia with 9,000 employees and more than 20 health centers, is targeted for later this month.

Targeted for implementation early in December are NuHealth System, Ochsner Health Systems and St. Barnabas Healthcare System with all to be installed and utilizing the SampleMD solution before the end of the year. Additionally the Allscripts integration of SampleMD is on track for launch in December to their ePrescribing providers throughout the country.

"This is a exciting time for SampleMD," said David Harrell, Chairman and Founder of OPTIMIZERx. "To have our healthcare partners utilizing the SampleMD solution within their organizations, helping patients to afford and stay on their medications, is very rewarding. We look forward to the additional systems coming on board by the end of the year and are excited by the committed increase of participation from both pharmaceutical manufacturers and healthcare providers alike."

For more information on OPTIMIZERx Corp., go to www.optimizerxcorp.com or www.samplemd.com.

About OPTIMIZERx Corporation

OPTIMIZERx Corporation provides unique platforms to help patients better afford and comply to their medicines and healthcare products, while offering pharmaceutical and healthcare companies effective ways to expand patient awareness, access and adherence to their brands. For more information about OPTIMIZERx Corp.: http://www.optimizerxcorp.com.

'SAFE HARBOR'

This press release contains forward-looking statements within the definition of Section 27A of the Securities Act of 1933, as amended and such section 21E of the Securities Act of 1934, amended. These forward-looking statements should not be used to make an investment decision. The words 'estimate,' 'possible' and 'seeking' and similar expressions identify forward-looking statements, which speak only as to the date the statement was made. The company undertakes no obligation to publicly update or revise any forward-looking statements, whether because of new information, future events, or otherwise. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted, or quantified. Future events and actual results could differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward-looking statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks.

Contact: David Harrell 248-651-6568