| RTW Investments, LP | Institution | 6.331.001 | 4,65% | US$ 8,42M | 2026-03-31 |
| Propel Bio Management, LLC | Institution | 2.611.916 | 1,92% | US$ 3,47M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 2.317.176 | 1,70% | US$ 3,08M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 2.000.025 | 1,47% | US$ 2,66M | 2026-03-31 |
| Marshall Wace LLP | Institution | 1.944.530 | 1,43% | US$ 2,59M | 2026-03-31 |
| Millennium Management LLC | Institution | 1.544.325 | 1,14% | US$ 2,05M | 2026-03-31 |
| Simplify Asset Management Inc. | Institution | 1.506.405 | 1,11% | US$ 2,00M | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 1.085.683 | 0,80% | US$ 1,44M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 851.325 | 0,63% | US$ 1,13M | 2026-03-31 |
| Lion Point Capital, LP | Institution | 820.000 | 0,60% | US$ 1,09M | 2026-03-31 |
| The Toronto-Dominion Bank | Institution | 750.000 | 0,55% | US$ 997,50k | 2026-03-31 |
| Morgan Stanley | Institution | 724.141 | 0,53% | US$ 963,11k | 2026-03-31 |
| Boxer Capital Management, LLC | Institution | 666.666 | 0,49% | US$ 886,67k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 519.046 | 0,38% | US$ 690,33k | 2026-03-31 |
| UBS Asset Management AG | Institution | 494.908 | 0,36% | US$ 658,23k | 2026-03-31 |
| Squarepoint OPS LLC | Institution | 336.825 | 0,25% | US$ 447,98k | 2026-03-31 |
| Seven Fleet Capital Management LP | Institution | 333.333 | 0,25% | US$ 443,33k | 2026-03-31 |
| Aptus Capital Advisors, LLC | Institution | 280.250 | 0,21% | US$ 372,73k | 2026-03-31 |
| Guardian Wealth Advisors, LLC | Institution | 280.250 | 0,21% | US$ 372,73k | 2026-03-31 |
| AMH Equity, Ltd. | Institution | 231.671 | 0,17% | US$ 308,12k | 2025-09-30 |
| Citadel Advisors LLC | Institution | 196.696 | 0,14% | US$ 261,61k | 2026-03-31 |
| LPL Financial LLC | Institution | 193.373 | 0,14% | US$ 257,19k | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 176.504 | 0,13% | US$ 234,75k | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 168.675 | 0,12% | US$ 224,34k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 159.669 | 0,12% | US$ 212,36k | 2026-03-31 |
| Simplex Trading, LLC | Institution | 149.291 | 0,11% | US$ 198,56k | 2026-03-31 |
| Quadrature Capital Limited | Institution | 149.105 | 0,11% | US$ 198,31k | 2026-03-31 |
| Valeo Financial Advisors, LLC | Institution | 130.699 | 0,10% | US$ 173,83k | 2026-03-31 |
| Group One Trading LLC | Institution | 129.764 | 0,10% | US$ 172,59k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 129.705 | 0,10% | US$ 172,51k | 2026-03-31 |
| XTX Markets Limited | Institution | 120.602 | 0,09% | US$ 160,40k | 2026-03-31 |
| Tru Independence Asset Management 2, LLC | Institution | 100.000 | 0,07% | US$ 133,00k | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 100.000 | 0,07% | US$ 133,00k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 62.256 | 0,05% | US$ 82,80k | 2026-03-31 |
| Cambridge Investment Research Advisors, Inc. | Institution | 59.620 | 0,04% | US$ 79,29k | 2026-03-31 |
| October Effect Ltd. | Institution | 51.950 | 0,04% | US$ 69,09k | 2026-03-31 |
| SG Americas Securities, LLC | Institution | 42.512 | 0,03% | US$ 56,54k | 2026-03-31 |
| Invesco Capital Management LLC | Institution | 41.356 | 0,03% | US$ 55,00k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 40.789 | 0,03% | US$ 54,25k | 2026-03-31 |
| Abaris Investment Management AG | Institution | 40.000 | 0,03% | US$ 53,20k | 2025-12-31 |
| Northern Trust Global Investments | Institution | 38.779 | 0,03% | US$ 51,58k | 2026-03-31 |
| Focus Partners Wealth, LLC | Institution | 36.000 | 0,03% | US$ 47,88k | 2026-03-31 |
| Mariner, LLC | Institution | 30.830 | 0,02% | US$ 41,00k | 2026-03-31 |
| Bay Rivers Group, Inc. | Institution | 29.911 | 0,02% | US$ 39,78k | 2026-03-31 |