| Charms Investments Limited Inc. | Institution | 1.300.000 | 12,81% | US$ 585,00k | 2026-06-02 |
| Deerfield Management Company, L.P. | Institution | 355.578 | 3,50% | US$ 160,01k | 2026-06-16 |
| Mr. Menachem Shalom | Insider | 300.000 | 2,96% | US$ 135,00k | 2026-04-10 |
| Deerfield Healthcare Innovations Fund II, L.P. | Institution | 177.789 | 1,75% | US$ 80,01k | 2026-06-16 |
| Deerfield Private Design Fund V, L.P. | Institution | 177.789 | 1,75% | US$ 80,01k | 2026-06-16 |
| Blackwell Partners LLC Series A | Institution | 131.269 | 1,29% | US$ 59,07k | 2025-04-11 |
| Nantahala Capital Management, LLC | Institution | 114.795 | 1,13% | US$ 51,66k | 2026-03-31 |
| AIGH Investment Partners | Institution | 62.259 | 0,61% | US$ 28,02k | 2025-04-11 |
| Rodney Hodges | Insider | 48.684 | 0,48% | US$ 21,91k | 2026-03-31 |
| AMR Action Fund GP, LLC | Institution | 46.152 | 0,45% | US$ 20,77k | 2024-09-30 |
| Aigh Capital Management, LLC | Institution | 38.175 | 0,38% | US$ 17,18k | 2025-12-31 |
| AMR Action Fund, L.P. | Institution | 34.263 | 0,34% | US$ 15,42k | 2024-09-30 |
| Nimble Ventures, LLC | Institution | 26.853 | 0,26% | US$ 12,08k | 2024-09-30 |
| WVP Emerging Manager Onshore Fund, LLC - AIGH Series | Institution | 20.212 | 0,20% | US$ 9,10k | 2025-04-11 |
| Ikarian Capital, LLC | Institution | 19.473 | 0,19% | US$ 8,76k | 2026-03-31 |
| Morgan Stanley | Institution | 19.100 | 0,19% | US$ 8,60k | 2026-03-31 |
| JPMorgan Chase & Co. | Institution | 14.135 | 0,14% | US$ 6,36k | 2026-03-31 |
| AMR Action Fund, Scsp. | Institution | 11.889 | 0,12% | US$ 5,35k | 2024-09-30 |
| Jane Street Group, LLC | Institution | 11.829 | 0,12% | US$ 5,32k | 2026-03-31 |
| Ms. Liat Bidas | Insider | 5.000 | 0,05% | US$ 2,25k | 2026-06-02 |
| Mr. Guy Arieli | Insider | 5.000 | 0,05% | US$ 2,25k | 2026-06-02 |
| Mr. Shaked Ran | Insider | 5.000 | 0,05% | US$ 2,25k | 2026-06-02 |
| Mr. Reuven Yeganeh | Insider | 5.000 | 0,05% | US$ 2,25k | 2026-06-02 |
| Barclays PLC | Institution | 1.316 | 0,01% | US$ 592,20 | 2026-03-31 |
| UBS Asset Management AG | Institution | 573 | 0,01% | US$ 257,85 | 2026-03-31 |
| Royal Bank of Canada | Institution | 251 | 0,00% | US$ 112,95 | 2026-03-31 |
| Osaic Wealth, Inc. | Institution | 200 | 0,00% | US$ 90,00 | 2026-03-31 |
| SBI Holdings, Inc. | Institution | 20 | 0,00% | US$ 9,00 | 2026-03-31 |
| Danske Capital AS (Estonia) | Institution | 1 | 0,00% | US$ 0,45 | 2026-03-31 |
| Carson Wealth Management Group | Institution | 1 | 0,00% | US$ 0,45 | 2026-03-31 |
| Cystic Fibrosis Foundation | Institution | 0 | 0,00% | - | 2026-06-02 |
| Dr. Russell Greig | Insider | 0 | 0,00% | - | 2026-06-02 |
| Dr. Alan Moses | Insider | 0 | 0,00% | - | 2026-06-02 |
| Alyeska Investment Group, L.P. | Institution | 0 | 0,00% | - | 2026-06-02 |
| Citadel Advisors LLC | Institution | 0 | 0,00% | - | 2026-03-31 |
| Mr. Jonathan Solomon | Insider | 0 | 0,00% | - | 2026-06-02 |
| Ms. Marina Wolfson | Insider | 0 | 0,00% | - | 2026-06-02 |
| Alyeska Master Fund, L.P. | Institution | 0 | 0,00% | - | 2026-06-02 |
| Clear Street LLC | Institution | 0 | 0,00% | - | 2026-03-31 |
| Dr. Merav Bassan | Insider | 0 | 0,00% | - | 2026-02-03 |
| Mr. James Flynn | Insider | 0 | 0,00% | - | 2026-06-16 |
| Mr. Jonathan Leff | Insider | 0 | 0,00% | - | 2026-02-03 |
| Mr. Edward Williams | Insider | 0 | 0,00% | - | 2026-02-03 |
| Dr. Jesse Goodman | Insider | 0 | 0,00% | - | 2026-02-03 |
| Mr. Gregory Merril | Insider | 0 | 0,00% | - | 2026-02-03 |
| Ms. Susan Blum | Insider | 0 | 0,00% | - | 2026-02-03 |
| Blackstone Inc. | Institution | -10 | -0,00% | US$ -4,50 | 2026-03-31 |