| Novo Holdings A/S | Institution | 1.252.432.500 | 28,28% | US$ 61,50B | 2025-12-31 |
| BlackRock, Inc. | Institution | 180.706.418 | 4,08% | US$ 8,87B | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 105.005.400 | 2,37% | US$ 5,16B | 2026-05-31 |
| Norges Bank Investment Management | Institution | 71.646.463 | 1,62% | US$ 3,52B | 2025-12-31 |
| Geode Capital Management, LLC | Institution | 35.951.406 | 0,81% | US$ 1,77B | 2026-06-30 |
| Dodge & Cox | Institution | 35.579.250 | 0,80% | US$ 1,75B | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 28.205.211 | 0,64% | US$ 1,38B | 2026-05-31 |
| Amundi Asset Management SAS | Institution | 24.102.716 | 0,54% | US$ 1,18B | 2026-04-30 |
| T. Rowe Price Group, Inc. | Institution | 19.056.399 | 0,43% | US$ 935,72M | 2026-05-31 |
| JP Morgan Asset Management | Institution | 18.354.317 | 0,41% | US$ 901,24M | 2026-06-30 |
| State Street Global Advisors, Inc. | Institution | 17.887.525 | 0,40% | US$ 878,32M | 2026-06-30 |
| Loomis, Sayles & Company, L.P. | Institution | 17.720.503 | 0,40% | US$ 870,12M | 2026-04-30 |
| Capital Research and Management Company | Institution | 17.291.576 | 0,39% | US$ 849,06M | 2026-03-31 |
| Flossbach von Storch SE | Institution | 17.256.956 | 0,39% | US$ 847,36M | 2025-12-31 |
| Putnam LLC | Institution | 17.251.119 | 0,39% | US$ 847,07M | 2026-05-31 |
| Vanguard Asset Management, Limited | Institution | 14.625.662 | 0,33% | US$ 718,16M | 2026-04-30 |
| Deutsche Asset & Wealth Management | Institution | 14.279.971 | 0,32% | US$ 701,18M | 2026-04-30 |
| Invesco Ltd. | Institution | 13.024.639 | 0,29% | US$ 639,54M | 2026-05-29 |
| Teachers Insurance and Annuity Association-College Retirement Equities Fund | Institution | 12.241.404 | 0,28% | US$ 601,08M | 2026-05-31 |
| UBS Asset Management AG | Institution | 12.058.361 | 0,27% | US$ 592,10M | 2026-04-30 |
| Baillie Gifford & Co. | Institution | 11.728.736 | 0,26% | US$ 575,91M | 2026-03-31 |
| Causeway Capital Management LLC | Institution | 11.174.653 | 0,25% | US$ 548,70M | 2026-05-31 |
| Charles Schwab Investment Management, Inc. | Institution | 11.161.144 | 0,25% | US$ 548,04M | 2026-05-29 |
| Susquehanna International Group, LLP | Institution | 11.106.111 | 0,25% | US$ 545,34M | 2026-03-31 |
| Fisher Asset Management, LLC | Institution | 11.022.510 | 0,25% | US$ 541,23M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 10.285.278 | 0,23% | US$ 505,03M | 2026-05-29 |
| Folketrygdfondet | Institution | 9.080.820 | 0,21% | US$ 445,89M | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 8.768.388 | 0,20% | US$ 430,55M | 2026-06-30 |
| Canada Pension Plan Investment Board | Institution | 8.494.000 | 0,19% | US$ 417,08M | 2025-03-31 |
| Deka Investment GmbH | Institution | 8.197.000 | 0,19% | US$ 402,49M | 2025-12-31 |