| 2022-02-27 | Mr. Osama A. EldessoukyInsider | -3,14k | 76,36k | Other Disposition | 24,35 | 73,64k | -4,08% |
| 2026-05-19 | Mr. Frank D. LeeIndependent Director | -24,46k | 132,80k | Automatic Disposition | 5,43 | 49,34k | -33,14% |
| 2026-05-18 | Dr. Amy B. WechslerIndependent Director | 54,35k | 290,21k | Derivative Exercise and Retained Stock | 5,34 | 160,94k | 50,98% |
| 2026-05-18 | Mr. Frank D. LeeIndependent Director | 29,89k | 159,62k | Derivative Exercise and Retained Stock | 5,34 | 49,34k | 153,70% |
| 2026-05-18 | Mr. Frank D. LeeIndependent Director | -24,46k | 2,20k | Derivative Exercise and Sale | 5,34 - 5,43 | 49,34k | - |
| 2026-05-18 | Dr. Richard C. MulliganInsider | 54,35k | 290,21k | Derivative Exercise and Retained Stock | 5,34 | 155,62k | 53,67% |
| 2024-03-01 | Mr. Luc BonnefoyInsider | 1,92k | 13,97k | Derivative Exercise and Retained Stock | 7,29 | 22,79k | 9,17% |
| 2024-03-01 | Mr. Luc BonnefoyInsider | -1,03k | 0,00 | Other Disposition | - | 22,79k | -4,32% |
| 2023-03-03 | Mr. Osama A. EldessoukyInsider | -6,29k | 0,00 | Derivative Exercise and Sale | - | 111,51k | - |
| 2023-03-03 | Mr. Osama A. EldessoukyInsider | 11,80k | 0,00 | Derivative Exercise and Retained Stock | - | 111,51k | 11,83% |
| 2023-02-27 | Mr. Osama A. EldessoukyInsider | -4,87k | 0,00 | Derivative Exercise and Sale | - | 92,33k | - |
| 2023-02-27 | Mr. Osama A. EldessoukyInsider | 8,50k | 0,00 | Derivative Exercise and Retained Stock | - | 92,33k | 10,14% |
| 2026-04-30 | Mr. Mirza DautbegovicExec. VP & COO | -20,00k | 120,00k | Verkauf | 6,00 | 284,75k | -6,56% |
| 2026-04-30 | Mr. Mirza DautbegovicExec. VP & COO | -20,00k | 120,00k | Verkauf | 6,00 | 284,75k | -6,56% |
| 2026-02-26 | Ms. Seana CarsonExec. VP & General Counsel | 60,17k | 0,00 | Derivative Exercise and Retained Stock | - | 223,72k | 36,79% |
| 2026-02-28 | Mr. Jean-Jacques CharhonExec. VP & CFO | 99,61k | 592,70k | Derivative Exercise and Retained Stock | 5,95 | 186,41k | 114,77% |
| 2026-02-28 | Mr. Jean-Jacques CharhonExec. VP & CFO | -49,06k | 0,00 | Other Disposition | - | 186,41k | -20,84% |
| 2026-03-02 | Ms. Seana CarsonExec. VP & General Counsel | -137,92k | 0,00 | Other Derivative Disposition | - | 212,35k | -39,38% |
| 2026-02-28 | Ms. Seana CarsonExec. VP & General Counsel | 80,89k | 481,27k | Derivative Exercise and Retained Stock | 5,95 | 241,64k | 50,32% |
| 2026-03-02 | Ms. Seana CarsonExec. VP & General Counsel | -11,28k | 65,13k | Verkauf | 5,77 - 5,78 | 241,64k | -4,46% |
| 2026-02-28 | Ms. Seana CarsonExec. VP & General Counsel | -43,30k | 0,00 | Other Disposition | - | 241,64k | -15,20% |
| 2026-02-28 | Mr. Mirza DautbegovicExec. VP & COO | 130,61k | 777,11k | Derivative Exercise and Retained Stock | 5,95 | 304,75k | 75,00% |
| 2026-02-28 | Mr. Mirza DautbegovicExec. VP & COO | -49,44k | 0,00 | Other Disposition | - | 304,75k | -13,96% |
| 2026-02-28 | Mr. Thomas J. AppioCEO & Director | 180,70k | 1,08M | Derivative Exercise and Retained Stock | 5,95 | 861,13k | 26,56% |
| 2026-02-28 | Mr. Thomas J. AppioCEO & Director | -166,80k | 494,40k | Derivative Exercise and Sale | 5,95 | 861,13k | - |
| 2026-03-02 | Mr. Thomas J. AppioCEO & Director | -1,14M | 0,00 | Other Derivative Disposition | - | 1,34M | -45,83% |
| 2026-02-27 | Mr. Jean-Jacques CharhonExec. VP & CFO | -49,06k | 290,93k | Sale to Issuer | 5,93 | 186,40k | -20,84% |
| 2026-03-02 | Ms. Seana CarsonExec. VP & General Counsel | -11,28k | 65,13k | Automatic Disposition | 5,77 - 5,78 | 234,89k | -4,58% |
| 2026-02-27 | Ms. Seana CarsonExec. VP & General Counsel | -43,30k | 257,10k | Sale to Issuer | 5,93 - 5,95 | 234,89k | -15,56% |
| 2026-03-02 | Ms. Seana CarsonExec. VP & General Counsel | -137,92k | 820,64k | Other Disposition | 5,95 | 234,89k | -37,00% |
| 2026-02-27 | Mr. Thomas J. AppioCEO & Director | -166,80k | 990,79k | Sale to Issuer | 5,93 - 5,95 | 903,22k | -15,59% |
| 2026-03-02 | Mr. Thomas J. AppioCEO & Director | -1,14M | 6,77M | Other Disposition | 5,95 | 903,22k | -55,75% |
| 2026-02-26 | Mr. Mirza DautbegovicExec. VP & COO | 18,70k | 0,00 | Derivative Exercise and Retained Stock | - | 223,57k | 9,13% |
| 2026-02-26 | Mr. Mirza DautbegovicExec. VP & COO | -11,39k | 0,00 | Derivative Exercise and Sale | - | 223,57k | - |
| 2026-02-26 | Ms. Aimee J. LenarExec. VP of US Pharma | -17,58k | 106,17k | Sale to Issuer | 6,04 | 43,91k | -28,59% |
| 2026-02-27 | Ms. Seana CarsonExec. VP & General Counsel | -8,39k | 49,91k | Automatic Disposition | 5,95 | 208,58k | -3,87% |
| 2026-02-26 | Ms. Seana CarsonExec. VP & General Counsel | -32,21k | 194,55k | Sale to Issuer | 6,04 | 208,58k | -13,38% |
| 2026-02-26 | Mr. Jean-Jacques CharhonExec. VP & CFO | -35,98k | 217,30k | Sale to Issuer | 6,04 | 135,84k | -20,94% |
| 2026-02-26 | Mr. Thomas J. AppioCEO & Director | -116,50k | 703,67k | Sale to Issuer | 6,04 | 722,53k | -13,89% |
| 2022-11-03 | Mr. Frederick J. MunschInsider | -5,46k | 0,00 | Other Disposition | - | 21,57k | -20,19% |
| 2025-12-03 | Mr. Thomas Warren RossInsider | -11,50k | 80,50k | Verkauf | 7,00 | 0,00 | -100,00% |
| 2024-03-01 | Mr. Frederick J. MunschInsider | 3,95k | 34,59k | Derivative Exercise and Retained Stock | 7,82 - 9,89 | 0,00 | -100,00% |
| 2025-12-03 | Mr. Frederick J. MunschInsider | -21,57k | 150,98k | Verkauf | 7,00 | 0,00 | -100,00% |
| 2022-02-27 | Mr. Frederick J. MunschInsider | -1,21k | 29,44k | Other Disposition | 24,35 | 0,00 | -100,00% |
| 2022-11-03 | Mr. Frederick J. MunschInsider | 10,57k | 91,39k | Derivative Exercise and Retained Stock | 6,45 - 9,57 | 19,28k | 121,41% |
| 2023-05-03 | Mr. Frederick J. MunschInsider | -2,18k | 0,00 | Other Derivative Disposition | - | 4,58k | -32,25% |
| 2025-11-25 | Paulson & Co. Inc.Unternehmen | 2,50M | 15,63M | Kauf | 6,25 | 40,46M | 6,59% |
| 2025-08-19 | Mr. Jean-Jacques CharhonExec. VP & CFO | 99,62k | 776,06k | Derivative Exercise and Retained Stock | 7,79 | 99,62k | - |
| 2025-09-08 | Ms. Seana CarsonExec. VP & General Counsel | -13,37k | 97,73k | Automatic Disposition | 7,31 | 189,00k | -6,61% |
| 2025-09-05 | Ms. Seana CarsonExec. VP & General Counsel | -51,34k | 377,33k | Sale to Issuer | 7,35 | 189,00k | -21,36% |
| 2025-09-05 | Ms. Seana CarsonExec. VP & General Counsel | 95,90k | 704,89k | Derivative Exercise and Retained Stock | 7,35 | 209,13k | 84,70% |
| 2025-09-05 | Mr. Mirza DautbegovicExec. VP & COO | 40,64k | 298,69k | Derivative Exercise and Retained Stock | 7,35 | 204,88k | 24,74% |
| 2025-09-05 | Mr. Mirza DautbegovicExec. VP & COO | -24,75k | 0,00 | Derivative Exercise and Sale | 7,35 | 204,88k | - |
| 2022-06-21 | Dr. Richard C. MulliganInsider | 101,27k | 0,00 | Derivative Exercise and Retained Stock | - | 101,27k | - |
| 2021-06-21 | Dr. Amy B. WechslerIndependent Director | 106,60k | 0,00 | Derivative Exercise and Retained Stock | - | 106,60k | - |
| 2025-05-13 | Mr. Frank D. LeeIndependent Director | 35,36k | 0,00 | Derivative Exercise and Retained Stock | - | 19,45k | -222,22% |
| 2025-08-21 | Mr. Frank D. LeeIndependent Director | -15,91k | 121,89k | Verkauf | 7,66 | 19,45k | -45,00% |
| 2025-08-14 | Icahn Capital LPUnternehmen | -34,72M | 312,49M | Verkauf | 9,00 | 0,00 | -100,00% |
| 2025-08-14 | Paulson & Co. Inc.Unternehmen | 34,72M | 312,49M | Kauf | 9,00 | 70,76M | 96,35% |
| 2025-08-11 | Paulson & Co. Inc.Unternehmen | 3,24M | 21,27M | Kauf | 6,35 - 7,06 | 36,03M | 9,89% |
| 2025-07-15 | Ms. Aimee J. LenarExec. VP of US Pharma | -22,74k | 145,97k | Sale to Issuer | 6,42 | 25,38k | -47,25% |
| 2025-06-13 | Paulson & Co. Inc.Unternehmen | 3,56M | 21,17M | Kauf | 5,94 | 32,79M | 12,19% |
| 2025-06-13 | Paulson & Co. Inc.Unternehmen | 3,56M | 21,17M | Kauf | 5,94 | 23,40M | 17,96% |
| 2025-06-10 | Paulson & Co. Inc.Unternehmen | 2,79M | 14,70M | Kauf | 5,05 - 5,47 | 29,23M | 10,55% |