| General Atlantic Service Company, L.P. | Institution | 8.031.252 | 11,49% | US$ 272,66M | 2026-03-31 |
| FMR LLC | Institution | 6.284.472 | 8,99% | US$ 213,36M | 2026-03-31 |
| Foresite Capital Management, LLC | Institution | 4.972.706 | 7,12% | US$ 168,82M | 2026-03-31 |
| venBio LLC | Institution | 4.639.304 | 6,64% | US$ 157,50M | 2026-03-31 |
| Viking Global Investors LP | Institution | 3.653.310 | 5,23% | US$ 124,03M | 2026-03-31 |
| EQT Life Sciences | Institution | 3.556.805 | 5,09% | US$ 120,75M | 2025-04-01 |
| Eqt Fund Management S.à R.L. | Institution | 3.424.609 | 4,90% | US$ 116,27M | 2026-03-31 |
| Deerfield Management Company, L.P. | Institution | 3.126.042 | 4,47% | US$ 106,13M | 2026-03-31 |
| Bain Capital Life Sciences Investors, LLC | Institution | 2.675.509 | 3,83% | US$ 90,83M | 2026-03-31 |
| Wellington Management Group LLP | Institution | 2.118.900 | 3,03% | US$ 71,94M | 2026-03-31 |
| Bain Capital Life Sciences Fund, L.P. | Institution | 2.058.794 | 2,95% | US$ 69,90M | 2025-09-30 |
| Commodore Capital LP | Institution | 1.918.970 | 2,75% | US$ 65,15M | 2026-03-31 |
| Novo Holdings A/S | Institution | 1.750.000 | 2,50% | US$ 59,41M | 2026-03-31 |
| Venrock Healthcare Capital Partners EG, L.P. | Institution | 1.629.483 | 2,33% | US$ 55,32M | 2025-06-30 |
| Saturn V Capital Management LP | Institution | 1.201.402 | 1,72% | US$ 40,79M | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 1.007.016 | 1,44% | US$ 34,19M | 2026-03-31 |
| Cormorant Asset Management, LP | Institution | 1.000.000 | 1,43% | US$ 33,95M | 2026-03-31 |
| Sofinnova Investments, Inc. | Institution | 818.328 | 1,17% | US$ 27,78M | 2026-03-31 |
| 5AM Venture Management, LLC | Institution | 797.600 | 1,14% | US$ 27,08M | 2026-03-31 |
| Polar Capital Holdings Plc | Institution | 781.016 | 1,12% | US$ 26,52M | 2026-03-31 |
| BlackRock, Inc. | Institution | 757.213 | 1,08% | US$ 25,71M | 2026-03-31 |
| Soleus Capital Management, L.P. | Institution | 702.052 | 1,00% | US$ 23,83M | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 645.533 | 0,92% | US$ 21,92M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 640.395 | 0,92% | US$ 21,74M | 2026-03-31 |
| Patient Square Capital, LP | Institution | 493.000 | 0,71% | US$ 16,74M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 486.856 | 0,70% | US$ 16,53M | 2026-03-31 |
| Elmind Capital, L.P. | Institution | 475.750 | 0,68% | US$ 16,15M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 462.251 | 0,66% | US$ 15,69M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 442.256 | 0,63% | US$ 15,01M | 2026-03-31 |
| Eversept Partners, L.P. | Institution | 406.960 | 0,58% | US$ 13,82M | 2026-03-31 |
| Venrock Healthcare Capital Partners III, L.P. | Institution | 380.109 | 0,54% | US$ 12,90M | 2025-06-30 |
| Baker Bros. Advisors LP | Institution | 375.000 | 0,54% | US$ 12,73M | 2026-03-31 |
| D. E. Shaw & Co., L.P. | Institution | 321.157 | 0,46% | US$ 10,90M | 2026-03-31 |
| Seven Fleet Capital Management LP | Institution | 316.697 | 0,45% | US$ 10,75M | 2026-03-31 |
| Mr. Hans J. G. C. Schikan | Insider | 315.167 | 0,45% | US$ 10,70M | 2026-06-30 |
| Tetragon Partners UK LLP | Institution | 221.611 | 0,32% | US$ 7,52M | 2026-03-31 |
| Hartford Funds Management Company, LLC | Institution | 217.897 | 0,31% | US$ 7,40M | 2026-05-31 |
| OrbiMed Advisors LLC | Institution | 205.400 | 0,29% | US$ 6,97M | 2026-03-31 |
| Kalehua Capital Management LLC | Institution | 198.772 | 0,28% | US$ 6,75M | 2026-03-31 |
| Millennium Management LLC | Institution | 181.946 | 0,26% | US$ 6,18M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 168.630 | 0,24% | US$ 5,72M | 2026-03-31 |
| Jones Hill Capital LP | Institution | 167.014 | 0,24% | US$ 5,67M | 2026-03-31 |
| Octagon Capital Advisors LP | Institution | 165.000 | 0,24% | US$ 5,60M | 2026-03-31 |