| Nextech Invest Ltd. | Institution | 7.162.637 | 6,92% | US$ 57,44M | 2026-03-31 |
| Nextech Crossover I SCSP | Institution | 7.162.637 | 6,92% | US$ 57,44M | 2025-06-30 |
| EcoR1 Capital, LLC | Institution | 6.728.116 | 6,50% | US$ 53,96M | 2026-03-31 |
| Ecor1 Capital Fund Qualified, L.P. | Institution | 6.283.426 | 6,07% | US$ 50,39M | 2025-07-29 |
| BlackRock, Inc. | Institution | 5.984.552 | 5,78% | US$ 48,00M | 2026-03-31 |
| Viking Global Investors LP | Institution | 5.824.533 | 5,63% | US$ 46,71M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 5.387.783 | 5,20% | US$ 43,21M | 2026-03-31 |
| SR One Capital Management, LP | Institution | 4.514.929 | 4,36% | US$ 36,21M | 2026-03-31 |
| VR Management, LLC | Institution | 4.319.765 | 4,17% | US$ 34,64M | 2026-03-31 |
| New Enterprise Associates, Inc. | Institution | 4.118.621 | 3,98% | US$ 33,03M | 2026-03-31 |
| Alkeon Capital Management, LLC | Institution | 3.751.818 | 3,62% | US$ 30,09M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 3.702.196 | 3,58% | US$ 29,69M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 3.687.007 | 3,56% | US$ 29,57M | 2026-03-31 |
| Column Group Venture Partners II, L.P. | Institution | 3.540.777 | 3,42% | US$ 28,40M | 2024-09-30 |
| The Column Group, LLC | Institution | 3.540.777 | 3,42% | US$ 28,40M | 2026-03-31 |
| Pfizer Venture Investments LLC | Institution | 3.442.940 | 3,33% | US$ 27,61M | 2026-03-31 |
| Venrock Healthcare Capital Partners EG, L.P. | Institution | 3.415.564 | 3,30% | US$ 27,39M | 2026-03-31 |
| OrbiMed Advisors LLC | Institution | 2.693.929 | 2,60% | US$ 21,61M | 2026-03-31 |
| AIHC Capital Management Limited | Institution | 2.459.551 | 2,38% | US$ 19,73M | 2026-03-31 |
| FMR LLC | Institution | 2.434.080 | 2,35% | US$ 19,52M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 2.422.741 | 2,34% | US$ 19,43M | 2026-03-31 |
| SR One Capital Opportunities Fund I, LP | Institution | 2.330.218 | 2,25% | US$ 18,69M | 2025-08-12 |
| First Turn Management, LLC | Institution | 2.017.284 | 1,95% | US$ 16,18M | 2026-03-31 |
| Artal Group S.A. | Institution | 1.990.617 | 1,92% | US$ 15,96M | 2026-03-31 |
| Vivo Capital, LLC | Institution | 1.848.786 | 1,79% | US$ 14,83M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.838.801 | 1,78% | US$ 14,75M | 2026-03-31 |
| MPM BioImpact LLC | Institution | 1.803.945 | 1,74% | US$ 14,47M | 2026-03-31 |
| Paradigm Biocapital Advisors LP | Institution | 1.701.217 | 1,64% | US$ 13,64M | 2026-03-31 |
| Morgan Stanley | Institution | 1.665.288 | 1,61% | US$ 13,36M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 1.471.290 | 1,42% | US$ 11,80M | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 1.452.705 | 1,40% | US$ 11,65M | 2026-03-31 |
| Integral Health Asset Management, LLC | Institution | 1.400.000 | 1,35% | US$ 11,23M | 2026-03-31 |
| Woodline Partners LP | Institution | 1.247.515 | 1,21% | US$ 10,01M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 1.215.827 | 1,17% | US$ 9,75M | 2026-03-31 |
| Royce & Associates, LP | Institution | 1.207.223 | 1,17% | US$ 9,68M | 2026-03-31 |
| Braidwell LP | Institution | 1.128.040 | 1,09% | US$ 9,05M | 2026-03-31 |
| Silverarc Capital Management, LLC | Institution | 1.100.010 | 1,06% | US$ 8,82M | 2026-03-31 |
| Bank of America Corporation | Institution | 1.043.159 | 1,01% | US$ 8,37M | 2026-03-31 |
| Invus Financial Advisors, LLC | Institution | 1.007.575 | 0,97% | US$ 8,08M | 2026-03-31 |
| Euclidean Capital LLC | Institution | 989.410 | 0,96% | US$ 7,94M | 2026-03-31 |
| ArrowMark Colorado Holdings, LLC | Institution | 960.517 | 0,93% | US$ 7,70M | 2026-03-31 |