| Federated Hermes, Inc. | Institution | 5.113.224 | 10,98% | US$ 21,02M | 2026-03-31 |
| Vivo Capital, LLC | Institution | 4.322.747 | 9,28% | US$ 17,77M | 2026-03-31 |
| Janus Henderson Group plc | Institution | 4.294.259 | 9,22% | US$ 17,65M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 4.258.600 | 9,14% | US$ 17,50M | 2026-03-31 |
| Logos Global Management, L.P. | Institution | 3.215.000 | 6,90% | US$ 13,21M | 2026-03-31 |
| Farallon Capital Management, L.L.C. | Institution | 2.365.000 | 5,08% | US$ 9,72M | 2026-03-31 |
| Coastlands Capital LP | Institution | 2.159.245 | 4,63% | US$ 8,87M | 2026-02-13 |
| Foresite Capital Management, LLC | Institution | 1.986.600 | 4,26% | US$ 8,16M | 2026-03-31 |
| Farallon Capital Offshore Investors II, L.P | Institution | 1.856.998 | 3,99% | US$ 7,63M | 2025-12-31 |
| Vanguard Capital Management, LLC | Institution | 1.845.831 | 3,96% | US$ 7,59M | 2026-03-31 |
| Ally Bridge Group | Institution | 1.655.500 | 3,55% | US$ 6,80M | 2026-03-31 |
| Spruce Street Capital LP | Institution | 1.655.500 | 3,55% | US$ 6,80M | 2026-03-31 |
| Adage Capital Partners, L.P. | Institution | 1.419.000 | 3,05% | US$ 5,83M | 2025-12-31 |
| Trails Edge Capital Partners, LP | Institution | 1.419.000 | 3,05% | US$ 5,83M | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 1.419.000 | 3,05% | US$ 5,83M | 2026-03-31 |
| C.H. Boehringer Sohn AG & Co. KG | Institution | 1.275.000 | 2,74% | US$ 5,24M | 2025-12-23 |
| Seven Fleet Capital Management LP | Institution | 1.137.730 | 2,44% | US$ 4,68M | 2026-03-31 |
| Dv Trading, LLC | Institution | 889.254 | 1,91% | US$ 3,65M | 2026-03-31 |
| Farallon Capital Partners, L.P. | Institution | 870.793 | 1,87% | US$ 3,58M | 2025-12-31 |
| Farallon Capital Institutional Partners, L.P. | Institution | 828.223 | 1,78% | US$ 3,40M | 2025-12-31 |
| Acuta Capital Partners, LLC | Institution | 709.500 | 1,52% | US$ 2,92M | 2026-03-31 |
| Millennium Management LLC | Institution | 708.291 | 1,52% | US$ 2,91M | 2026-03-31 |
| BlackRock, Inc. | Institution | 624.857 | 1,34% | US$ 2,57M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 338.735 | 0,73% | US$ 1,39M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 264.047 | 0,57% | US$ 1,09M | 2026-03-31 |
| Farallon Capital Institutional Partners II, L.P. | Institution | 259.677 | 0,56% | US$ 1,07M | 2025-12-31 |
| Farallon Capital F5 Master I, L.P. | Institution | 223.256 | 0,48% | US$ 917,58k | 2025-12-31 |
| Marshall Wace LLP | Institution | 218.759 | 0,47% | US$ 899,10k | 2026-03-31 |
| Four Crossings Institutional Partners V, L.P. | Institution | 213.323 | 0,46% | US$ 876,76k | 2025-12-31 |
| Dr. Remy Luthringer | Insider | 184.819 | 0,40% | US$ 759,61k | 2025-10-23 |
| Farallon Capital Institutional Partners III, L.P. | Institution | 168.861 | 0,36% | US$ 694,02k | 2025-12-31 |
| Susquehanna International Group, LLP | Institution | 119.131 | 0,26% | US$ 489,63k | 2026-03-31 |
| Farallon Capital (AM) Investors, L.P. | Institution | 118.723 | 0,25% | US$ 487,95k | 2025-12-31 |
| Northern Trust Global Investments | Institution | 93.308 | 0,20% | US$ 383,50k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 89.700 | 0,19% | US$ 368,67k | 2026-03-31 |
| UBS Asset Management AG | Institution | 67.570 | 0,15% | US$ 277,71k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 56.349 | 0,12% | US$ 231,59k | 2026-03-31 |
| Mr. Geoffrey Race | Insider | 51.324 | 0,11% | US$ 210,94k | 2025-10-23 |
| Apella Capital, LLC | Institution | 42.250 | 0,09% | US$ 173,65k | 2026-03-31 |
| Brendel Financial Advisors LLC | Institution | 41.799 | 0,09% | US$ 171,79k | 2026-03-31 |
| Bank of America Corporation | Institution | 39.970 | 0,09% | US$ 164,28k | 2026-03-31 |