| 2026-05-11 | Mr. Matthias BodenstedtCFO | -13,65k | 273,33k | Automatic Disposition | 20,02 | 1,17M | -1,15% |
| 2026-04-14 | Mr. Matthias BodenstedtCFO | -2,43k | 47,45k | Automatic Disposition | 19,56 | 1,19M | -0,20% |
| 2026-04-10 | Dr. Jorge Santos da SilvaCo-Founder, Interim Chair of the Board & CEO | -150,00k | 2,75M | Verkauf | 18,23 - 18,41 | 2,92M | -4,88% |
| 2026-04-09 | Mr. Matthias BodenstedtCFO | -87,80k | 1,66M | Automatic Disposition | 18,94 - 19,51 | 1,19M | -6,88% |
| 2026-03-31 | BVF Partners L.P.Unternehmen | -3,75M | 62,96M | Verkauf | 16,79 | 15,94M | -19,04% |
| 2025-12-19 | Mr. Matthias BodenstedtCFO | 294,47k | 0,00 | Derivative Exercise and Retained Stock | - | 922,01k | 46,93% |
| 2025-12-19 | Mr. Matthias BodenstedtCFO | -294,47k | 0,00 | Sale to Issuer | - | 0,00 | -100,00% |
| 2025-12-19 | Dr. Kristian ReichCo-Founder & Chief Scientific Officer | 35,39k | 0,00 | Derivative Exercise and Retained Stock | - | 3,01M | 1,19% |
| 2025-12-19 | Dr. Kristian ReichCo-Founder & Chief Scientific Officer | -35,39k | 0,00 | Sale to Issuer | - | 0,00 | -100,00% |
| 2025-12-19 | Dr. Jorge Santos da SilvaCo-Founder, Interim Chair of the Board & CEO | 196,32k | 0,00 | Derivative Exercise and Retained Stock | - | 3,07M | 6,82% |
| 2025-12-19 | Dr. Jorge Santos da SilvaCo-Founder, Interim Chair of the Board & CEO | -196,32k | 0,00 | Sale to Issuer | - | 0,00 | -100,00% |
| 2025-12-08 | Dr. Jorge Santos da SilvaCo-Founder, Interim Chair of the Board & CEO | -200,00k | 2,97M | Verkauf | 14,49 - 15,08 | 2,88M | -6,50% |
| 2025-12-08 | Dr. Kristian ReichCo-Founder & Chief Scientific Officer | -202,91k | 3,01M | Verkauf | 14,43 - 15,08 | 2,97M | -6,39% |
| 2025-10-08 | Mr. Matthias BodenstedtCFO | 10,87k | 98,81k | Kauf | 9,09 | 627,54k | 1,76% |
| 2025-09-29 | Cormorant Asset Management, LPUnternehmen | -2,81M | 18,55M | Verkauf | 6,61 - 6,96 | 1,99M | -58,45% |
| 2025-09-29 | Cormorant Asset Management, LPUnternehmen | -3,69M | 28,32M | Verkauf | 7,58 - 9,38 | 1,99M | -64,94% |
| 2025-09-02 | Dr. Kristian ReichCo-Founder & Chief Scientific Officer | 48,98k | 0,00 | Derivative Exercise and Retained Stock | - | 3,18M | 1,57% |
| 2025-09-02 | Dr. Kristian ReichCo-Founder & Chief Scientific Officer | -48,98k | 0,00 | Sale to Issuer | - | 35,39k | -58,05% |
| 2025-07-03 | Mrs. Catherine MoukheibirIndependent Director | -23,50k | 1,15M | Derivative Exercise and Sale | 48,79 | 0,00 | - |