| Velan Capital Partners LP | Institution | 2.668.395 | 9,53% | US$ 1,24M | 2026-03-31 |
| Integrated Core Strategies (US) LLC | Institution | 1.624.076 | 5,80% | US$ 756,82k | 2026-02-18 |
| Millennium Management LLC | Institution | 1.617.531 | 5,78% | US$ 753,77k | 2026-03-31 |
| Acorn Bioventures | Institution | 1.411.492 | 5,04% | US$ 657,76k | 2026-03-31 |
| Kingdon Capital Management, L.L.C. | Institution | 1.352.106 | 4,83% | US$ 630,08k | 2026-03-31 |
| Morgan Stanley | Institution | 1.333.420 | 4,76% | US$ 621,37k | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.172.597 | 4,19% | US$ 546,43k | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 1.100.726 | 3,93% | US$ 512,94k | 2026-03-31 |
| Abingworth LLP | Institution | 1.066.189 | 3,81% | US$ 496,84k | 2026-03-31 |
| Abingworth Bioventures VII LP | Institution | 1.066.189 | 3,81% | US$ 496,84k | 2026-02-18 |
| Qiming Weichuang Venture Capital Management (Shanghai) Company Limited | Institution | 928.964 | 3,32% | US$ 432,90k | 2025-09-30 |
| Qiming U.S. Healthcare Fund II, L.P. | Institution | 928.964 | 3,32% | US$ 432,90k | 2025-09-30 |
| Acorn Bioventures 2, L.P. | Institution | 862.166 | 3,08% | US$ 401,77k | 2026-01-23 |
| Acorn Bioventures, L.P. | Institution | 624.326 | 2,23% | US$ 290,94k | 2026-01-23 |
| Boothbay Fund Management, LLC | Institution | 582.751 | 2,08% | US$ 271,56k | 2026-03-31 |
| Lion Point Capital, LP | Institution | 465.000 | 1,66% | US$ 216,69k | 2026-03-31 |
| Jacobs Levy Equity Management Inc | Institution | 322.273 | 1,15% | US$ 150,18k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 317.677 | 1,13% | US$ 148,04k | 2026-03-31 |
| Bank of America Corporation | Institution | 293.259 | 1,05% | US$ 136,66k | 2026-03-31 |
| Soleus Capital Management, L.P. | Institution | 276.312 | 0,99% | US$ 128,76k | 2026-03-31 |
| BlackRock, Inc. | Institution | 242.061 | 0,86% | US$ 112,80k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 177.500 | 0,63% | US$ 82,72k | 2026-03-31 |
| Knott Partners Management, LLC | Institution | 160.789 | 0,57% | US$ 74,93k | 2026-03-31 |
| Soleus Capital LLC | Institution | 157.400 | 0,56% | US$ 73,35k | 2026-03-31 |
| Soleus Private Equity Fund III LP | Institution | 157.400 | 0,56% | US$ 73,35k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 149.943 | 0,54% | US$ 69,87k | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 140.000 | 0,50% | US$ 65,24k | 2026-03-31 |
| The Quarry LP | Institution | 131.529 | 0,47% | US$ 61,29k | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 128.862 | 0,46% | US$ 60,05k | 2026-03-31 |
| Soleus Capital Master Fund, L.P. | Institution | 118.912 | 0,42% | US$ 55,41k | 2026-03-31 |
| UBS Asset Management AG | Institution | 81.117 | 0,29% | US$ 37,80k | 2026-03-31 |
| Verdad Advisers, L.P. | Institution | 73.967 | 0,26% | US$ 34,47k | 2026-03-31 |
| Squarepoint OPS LLC | Institution | 64.915 | 0,23% | US$ 30,25k | 2026-03-31 |
| IEQ Capital, LLC | Institution | 51.428 | 0,18% | US$ 23,97k | 2026-03-31 |
| Marshall Wace LLP | Institution | 45.656 | 0,16% | US$ 21,28k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 44.699 | 0,16% | US$ 20,83k | 2026-03-31 |
| Nine Masts Capital Limited | Institution | 44.165 | 0,16% | US$ 20,58k | 2026-03-31 |
| Osaic Advisory Services, LLC | Institution | 40.850 | 0,15% | US$ 19,04k | 2026-03-31 |
| XTX Markets Limited | Institution | 39.431 | 0,14% | US$ 18,37k | 2026-03-31 |
| Diker Management LLC | Institution | 35.000 | 0,13% | US$ 16,31k | 2026-03-31 |
| Northern Trust Global Investments | Institution | 34.576 | 0,12% | US$ 16,11k | 2026-03-31 |
| Simplex Trading, LLC | Institution | 29.273 | 0,10% | US$ 13,64k | 2026-03-31 |
| Readystate Asset Management LP | Institution | 27.499 | 0,10% | US$ 12,81k | 2026-03-31 |