| RA Capital Management, L.P. | Institution | 17.754.430 | 9,84% | US$ 39,06M | 2026-03-31 |
| RA Capital Healthcare Fund, L.P. | Institution | 17.754.430 | 9,84% | US$ 39,06M | 2026-01-09 |
| TCG Crossover Management, LLC | Institution | 17.754.430 | 9,84% | US$ 39,06M | 2026-03-31 |
| Bayer Aktiengesellschaft | Institution | 12.675.838 | 7,03% | US$ 27,89M | 2025-11-15 |
| Versant Venture Management, LLC | Institution | 12.166.109 | 6,75% | US$ 26,77M | 2026-03-31 |
| Versant Venture Capital VI | Institution | 11.452.014 | 6,35% | US$ 25,19M | 2025-11-15 |
| Deep Track Capital, LP | Institution | 9.487.745 | 5,26% | US$ 20,87M | 2026-03-31 |
| TCG Crossover Fund III, L.P. | Institution | 8.877.215 | 4,92% | US$ 19,53M | 2026-01-09 |
| TCG Crossover Fund II, L.P. | Institution | 8.877.215 | 4,92% | US$ 19,53M | 2026-01-09 |
| RTW Investments, LP | Institution | 8.695.652 | 4,82% | US$ 19,13M | 2026-03-31 |
| VR Management, LLC | Institution | 8.695.652 | 4,82% | US$ 19,13M | 2026-03-31 |
| Commodore Capital Master LP | Institution | 8.695.652 | 4,82% | US$ 19,13M | 2026-01-09 |
| Commodore Capital LP | Institution | 8.695.652 | 4,82% | US$ 19,13M | 2026-03-31 |
| Deep Track Biotechnology Master Fund, Ltd | Institution | 7.220.313 | 4,00% | US$ 15,88M | 2026-01-08 |
| Venrock Healthcare Capital Partners EG, L.P. | Institution | 7.139.130 | 3,96% | US$ 15,71M | 2026-01-09 |
| FUJIFILM Holdings Corporation | Institution | 6.955.207 | 3,86% | US$ 15,30M | 2025-11-15 |
| Point72 Asset Management, L.P. | Institution | 5.964.678 | 3,31% | US$ 13,12M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 5.686.204 | 3,15% | US$ 12,51M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 5.017.733 | 2,78% | US$ 11,04M | 2026-03-31 |
| Point72 Associates, LLC | Institution | 4.725.639 | 2,62% | US$ 10,40M | 2026-01-02 |
| Millennium Management LLC | Institution | 4.667.063 | 2,59% | US$ 10,27M | 2026-03-31 |
| Spruce Street Capital LP | Institution | 4.059.054 | 2,25% | US$ 8,93M | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 3.789.538 | 2,10% | US$ 8,34M | 2026-03-31 |
| Dr. Brent Pfeiffenberger | Insider | 3.679.786 | 2,04% | US$ 8,10M | 2026-05-15 |
| Boxer Capital Management, LLC | Institution | 3.174.603 | 1,76% | US$ 6,98M | 2024-10-10 |
| Woodline Partners LP | Institution | 3.043.478 | 1,69% | US$ 6,70M | 2026-03-31 |
| Seven Fleet Capital Management LP | Institution | 2.947.826 | 1,63% | US$ 6,49M | 2026-03-31 |
| Trails Edge Capital Partners, LP | Institution | 2.449.993 | 1,36% | US$ 5,39M | 2026-03-31 |
| Dafna Capital Management, LLC | Institution | 2.434.353 | 1,35% | US$ 5,36M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 2.371.430 | 1,31% | US$ 5,22M | 2026-03-31 |
| Deep Track Special Opportunities Fund, Lp | Institution | 1.918.261 | 1,06% | US$ 4,22M | 2026-01-08 |
| BlackRock, Inc. | Institution | 1.524.422 | 0,85% | US$ 3,35M | 2026-03-31 |
| Venrock Healthcare Capital Partners III, L.P. | Institution | 1.414.783 | 0,78% | US$ 3,11M | 2026-01-09 |
| Rock Springs Capital Management LP | Institution | 1.304.347 | 0,72% | US$ 2,87M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.301.664 | 0,72% | US$ 2,86M | 2026-03-31 |
| Casdin Capital, LLC | Institution | 1.228.190 | 0,68% | US$ 2,70M | 2026-03-31 |
| Syncona Investment Management Limited | Institution | 1.213.056 | 0,67% | US$ 2,67M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 906.827 | 0,50% | US$ 2,00M | 2026-03-31 |
| Versant Vantage II, L.P. | Institution | 714.095 | 0,40% | US$ 1,57M | 2025-11-15 |
| Vanguard Fiduciary Trust Company | Institution | 692.963 | 0,38% | US$ 1,52M | 2026-03-31 |
| Marshall Wace LLP | Institution | 673.584 | 0,37% | US$ 1,48M | 2026-03-31 |
| Dr. Gregory Russotti | Insider | 608.200 | 0,34% | US$ 1,34M | 2026-03-12 |
| Mr. Douglas Carr | Insider | 506.997 | 0,28% | US$ 1,12M | 2026-05-04 |
| Mr. Joseph Jimenez | Insider | 494.345 | 0,27% | US$ 1,09M | 2025-04-15 |
| State Street Global Advisors, Inc. | Institution | 386.723 | 0,21% | US$ 850,79k | 2026-03-31 |
| Acadian Asset Management LLC | Institution | 278.075 | 0,15% | US$ 611,77k | 2026-03-31 |