| OrbiMed Advisors LLC | Institution | 1.439.983 | 12,77% | US$ 8,74M | 2026-04-29 |
| OrbiMed Private Investments VI, LP | Institution | 1.218.240 | 10,80% | US$ 7,39M | 2026-04-29 |
| BVF Partners L.P. | Institution | 1.110.002 | 9,84% | US$ 6,74M | 2026-03-31 |
| CHI Advisors LLC | Institution | 959.337 | 8,51% | US$ 5,82M | 2026-03-31 |
| Cable Car Capital LLC | Institution | 754.749 | 6,69% | US$ 4,58M | 2026-03-31 |
| Funicular Fund, LP | Institution | 643.933 | 5,71% | US$ 3,91M | 2025-12-29 |
| Biotechnology Value Fund L.P. | Institution | 593.189 | 5,26% | US$ 3,60M | 2026-03-31 |
| Omega Fund Management, LLC | Institution | 455.361 | 4,04% | US$ 2,76M | 2026-03-31 |
| Omega Advisors, Inc. | Institution | 454.982 | 4,03% | US$ 2,76M | 2026-04-14 |
| Omega Fund VI, L.P. | Institution | 454.982 | 4,03% | US$ 2,76M | 2026-04-14 |
| Biotechnology Value Fund II, L.P. | Institution | 433.269 | 3,84% | US$ 2,63M | 2026-03-31 |
| RTW Investments, LP | Institution | 334.445 | 2,97% | US$ 2,03M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 325.155 | 2,88% | US$ 1,97M | 2026-03-31 |
| Atlas Venture Fund X, L.P. | Institution | 241.800 | 2,14% | US$ 1,47M | 2025-07-25 |
| BML Capital Management, LLC | Institution | 200.730 | 1,78% | US$ 1,22M | 2026-03-31 |
| HighLight Capital | Institution | 188.042 | 1,67% | US$ 1,14M | 2025-07-25 |
| BlackRock, Inc. | Institution | 129.214 | 1,15% | US$ 784,33k | 2026-03-31 |
| Citadel Advisors LLC | Institution | 124.345 | 1,10% | US$ 754,77k | 2026-03-31 |
| Atlas Venture Fund XI, L.P. | Institution | 103.494 | 0,92% | US$ 628,21k | 2025-07-25 |
| Renaissance Technologies LLC | Institution | 81.696 | 0,72% | US$ 495,89k | 2026-03-31 |
| Atlas Venture Opportunity Fund I | Institution | 72.885 | 0,65% | US$ 442,41k | 2025-07-25 |
| Biotechnology Value Trading Fund OS LP | Institution | 66.808 | 0,59% | US$ 405,52k | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 66.666 | 0,59% | US$ 404,66k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 59.929 | 0,53% | US$ 363,77k | 2026-03-31 |
| Trails Edge Capital Partners, LP | Institution | 54.253 | 0,48% | US$ 329,32k | 2026-04-14 |
| New Enterprise Associates, Inc. | Institution | 50.005 | 0,44% | US$ 303,53k | 2026-03-31 |
| HSBC Global Asset Management (UK) Limited | Institution | 34.884 | 0,31% | US$ 211,75k | 2026-03-31 |
| OrbiMed Genesis Master Fund, L.P. | Institution | 33.798 | 0,30% | US$ 205,15k | 2026-04-29 |
| Rangeley Capital, LLC | Institution | 32.590 | 0,29% | US$ 197,82k | 2026-03-31 |
| Sofinnova Investments, Inc. | Institution | 31.884 | 0,28% | US$ 193,54k | 2026-03-31 |
| Nano-Cap New Millennium Advisors, Llc | Institution | 30.000 | 0,27% | US$ 182,10k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 27.286 | 0,24% | US$ 165,63k | 2026-03-31 |
| Jacobs Levy Equity Management Inc | Institution | 26.663 | 0,24% | US$ 161,84k | 2026-03-31 |
| Shay Capital LLC | Institution | 19.130 | 0,17% | US$ 116,12k | 2026-03-31 |
| Aldebaran Capital, LLC | Institution | 18.566 | 0,16% | US$ 112,70k | 2026-03-31 |
| XTX Markets Limited | Institution | 15.112 | 0,13% | US$ 91,73k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 13.909 | 0,12% | US$ 84,43k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 13.210 | 0,12% | US$ 80,18k | 2026-03-31 |
| Prelude Capital Management, LLC | Institution | 12.990 | 0,12% | US$ 78,85k | 2026-03-31 |
| Bridgeway Capital Management, LLC | Institution | 12.774 | 0,11% | US$ 77,54k | 2025-09-30 |
| The Goldman Sachs Group, Inc. | Institution | 11.458 | 0,10% | US$ 69,55k | 2026-03-31 |
| MSI BVF SPV, LLC | Institution | 11.010 | 0,10% | US$ 66,83k | 2025-07-25 |
| Barclays PLC | Institution | 10.959 | 0,10% | US$ 66,52k | 2026-03-31 |
| Morgan Stanley | Institution | 10.092 | 0,09% | US$ 61,26k | 2026-03-31 |