| RA Capital Management, L.P. | Institution | 63.771.366 | 9,94% | US$ 80,99M | 2026-03-31 |
| Soleus Capital Master Fund, L.P. | Institution | 41.508.659 | 6,47% | US$ 52,72M | 2026-03-31 |
| Soleus Capital Management, L.P. | Institution | 41.508.659 | 6,47% | US$ 52,72M | 2026-03-31 |
| Deep Track Biotechnology Master Fund, Ltd | Institution | 35.000.000 | 5,46% | US$ 44,45M | 2025-03-18 |
| Deep Track Capital, LP | Institution | 31.720.278 | 4,94% | US$ 40,28M | 2026-03-31 |
| Vivo Opportunity Fund Holdings, L.P | Institution | 27.225.292 | 4,24% | US$ 34,58M | 2025-03-01 |
| Point72 Asset Management, L.P. | Institution | 20.457.134 | 3,19% | US$ 25,98M | 2026-03-31 |
| Eversept Partners, L.P. | Institution | 18.834.883 | 2,94% | US$ 23,92M | 2026-03-31 |
| Nantahala Capital Management, LLC | Institution | 11.225.000 | 1,75% | US$ 14,26M | 2026-03-31 |
| Vivo Capital, LLC | Institution | 8.671.797 | 1,35% | US$ 11,01M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 6.836.318 | 1,07% | US$ 8,68M | 2026-03-31 |
| Pale Fire Capital SE | Institution | 4.888.304 | 0,76% | US$ 6,21M | 2026-03-31 |
| Segall Bryant & Hamill, LLC | Institution | 4.740.048 | 0,74% | US$ 6,02M | 2026-03-31 |
| Candriam, Société En Commandite Par Actions | Institution | 3.921.476 | 0,61% | US$ 4,98M | 2026-03-31 |
| Vestal Point Capital, LP | Institution | 2.540.000 | 0,40% | US$ 3,23M | 2026-03-31 |
| Edmond de Rothschild Asset Management (France) | Institution | 2.330.000 | 0,36% | US$ 2,96M | 2026-03-31 |
| Nan Fung Trinity (HK) Limited | Institution | 1.373.550 | 0,21% | US$ 1,74M | 2026-03-31 |
| Hudson River Trading LLC | Institution | 1.214.752 | 0,19% | US$ 1,54M | 2026-03-31 |
| British & American Investment Trust PLC | Institution | 1.070.777 | 0,17% | US$ 1,36M | 2025-06-30 |
| World Investment Advisors, LLC | Institution | 1.033.779 | 0,16% | US$ 1,31M | 2026-03-31 |
| XTX Markets Limited | Institution | 961.159 | 0,15% | US$ 1,22M | 2026-03-31 |
| Virtus Investment Advisers, LLC | Institution | 620.795 | 0,10% | US$ 788,41k | 2026-03-31 |
| J. Goldman & Co., L.P. | Institution | 610.659 | 0,10% | US$ 775,54k | 2026-03-31 |
| Lion Point Capital, LP | Institution | 578.000 | 0,09% | US$ 734,06k | 2026-03-31 |