| AstraZeneca PLC | Institution | 16.000.000 | 22,04% | US$ 50,40M | 2025-01-23 |
| Bpifrance Participations SA | Institution | 5.873.247 | 8,09% | US$ 18,50M | 2025-12-03 |
| The B Group, Inc. | Institution | 3.281.501 | 4,52% | US$ 10,34M | 2026-03-31 |
| UBS Asset Management AG | Institution | 3.208.394 | 4,42% | US$ 10,11M | 2026-03-31 |
| Long Focus Capital Management LLC | Institution | 2.744.098 | 3,78% | US$ 8,64M | 2026-03-31 |
| Long Focus Capital Master, Ltd. | Institution | 2.510.101 | 3,46% | US$ 7,91M | 2024-12-31 |
| Lohas S.à R.L. | Institution | 1.743.678 | 2,40% | US$ 5,49M | 2025-02-15 |
| Dr. Andre Choulika | Insider | 1.054.913 | 1,45% | US$ 3,32M | 2025-02-15 |
| Caisse des Dépôts et Consignations | Institution | 1.039.906 | 1,43% | US$ 3,28M | 2025-12-03 |
| Sgbt Lux Viveoo | Institution | 415.000 | 0,57% | US$ 1,31M | 2025-02-15 |
| BlackRock, Inc. | Institution | 341.523 | 0,47% | US$ 1,08M | 2026-03-31 |
| Dr. David Sourdive | Insider | 293.624 | 0,40% | US$ 924,92k | 2025-02-15 |
| Viveoo Sarl | Institution | 288.041 | 0,40% | US$ 907,33k | 2025-02-15 |
| Financiere Arbevel | Institution | 280.420 | 0,39% | US$ 883,32k | 2025-06-30 |
| Nomura Investment Management Business Trust | Institution | 226.875 | 0,31% | US$ 714,66k | 2026-03-31 |
| BelleCapital A.G | Institution | 226.071 | 0,31% | US$ 712,12k | 2025-06-30 |
| Morgan Stanley | Institution | 86.776 | 0,12% | US$ 273,34k | 2026-03-31 |
| LPL Financial LLC | Institution | 84.345 | 0,12% | US$ 265,69k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 65.942 | 0,09% | US$ 207,72k | 2026-03-31 |
| Mr. Pierre Bastid | Insider | 55.900 | 0,08% | US$ 176,09k | 2025-02-15 |
| Dr. Philippe Duchateau | Insider | 52.264 | 0,07% | US$ 164,63k | 2025-02-15 |
| Citadel Advisors LLC | Institution | 44.315 | 0,06% | US$ 139,59k | 2026-03-31 |
| Marshall Wace LLP | Institution | 41.112 | 0,06% | US$ 129,50k | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 41.000 | 0,06% | US$ 129,15k | 2026-03-31 |
| Ms. Marie-Bleuenn Terrier | Insider | 39.618 | 0,05% | US$ 124,80k | 2025-02-15 |
| Mr. Stephan Reynier | Insider | 32.252 | 0,04% | US$ 101,59k | 2025-02-15 |
| Merchbanc, S.A., S.G.I.I.C | Institution | 30.000 | 0,04% | US$ 94,50k | 2025-09-30 |
| P & S VermÖGensberatungs Ag Performance & Sicherheit | Institution | 30.000 | 0,04% | US$ 94,50k | 2025-04-30 |
| Dr. Steven Doares | Insider | 24.310 | 0,03% | US$ 76,58k | 2025-02-15 |
| Hemenway Trust Company LLC | Institution | 24.000 | 0,03% | US$ 75,60k | 2026-03-31 |
| Ms. Kyung Nam-Wortman | Insider | 20.630 | 0,03% | US$ 64,98k | 2025-02-15 |
| Mr. Arthur Stril | Insider | 17.590 | 0,02% | US$ 55,41k | 2025-02-15 |
| XTX Markets Limited | Institution | 16.269 | 0,02% | US$ 51,25k | 2026-03-31 |
| Rhumbline Advisers Ltd Partnership | Institution | 15.085 | 0,02% | US$ 47,52k | 2026-03-31 |
| Lido Advisors, LLC | Institution | 10.094 | 0,01% | US$ 31,80k | 2026-03-31 |
| Global Retirement Partners, LLC | Institution | 7.038 | 0,01% | US$ 22,17k | 2025-12-31 |
| Harbour Investments, Inc. | Institution | 4.500 | 0,01% | US$ 14,18k | 2026-03-31 |
| National Bank Investments Inc. | Institution | 3.600 | 0,00% | US$ 11,34k | 2026-03-31 |
| Wells Fargo & Company | Institution | 3.150 | 0,00% | US$ 9,92k | 2026-03-31 |
| Tower Research Capital Europe Limited | Institution | 1.797 | 0,00% | US$ 5,66k | 2026-03-31 |
| Atlantic Union Bankshares Corporation | Institution | 1.500 | 0,00% | US$ 4,73k | 2026-03-31 |
| Quadrant Capital Group LLC | Institution | 944 | 0,00% | US$ 2,97k | 2026-03-31 |
| GAMMA Investing LLC | Institution | 734 | 0,00% | US$ 2,31k | 2026-03-31 |