| Sands Capital Management, LLC | Institution | 2.235.011 | 14,15% | US$ 2,14M | 2025-03-31 |
| Bering Partners II, L.P. | Institution | 2.113.513 | 13,38% | US$ 2,02M | 2026-06-25 |
| Bering Capital | Institution | 2.113.513 | 13,38% | US$ 2,02M | 2026-06-25 |
| Mr. Robert Wilson | Insider | 1.604.650 | 10,16% | US$ 1,53M | 2026-06-25 |
| Alafi Capital Company LLC | Institution | 1.583.153 | 10,02% | US$ 1,51M | 2025-07-22 |
| Sanderling Venture Partners VI, L.P. | Institution | 985.563 | 6,24% | US$ 942,10k | 2025-03-31 |
| Sanderling Venture Partners VI Co-investment Fund, L.P | Institution | 814.300 | 5,15% | US$ 778,39k | 2025-03-31 |
| Valence Life Sciences | Institution | 739.326 | 4,68% | US$ 706,72k | 2026-06-25 |
| Aisling Capital V, LP | Institution | 521.114 | 3,30% | US$ 498,13k | 2025-03-03 |
| Aisling Capital LLC | Institution | 521.114 | 3,30% | US$ 498,13k | 2025-03-03 |
| Mr. Eric Roberts | Insider | 511.140 | 3,24% | US$ 488,60k | 2026-06-25 |
| Sanderling Ventures VII | Institution | 435.148 | 2,75% | US$ 415,96k | 2025-03-31 |
| Stonepine Capital, L.P. | Institution | 367.371 | 2,33% | US$ 351,17k | 2025-03-31 |
| Dr. A. Leheny | Insider | 322.155 | 2,04% | US$ 307,95k | 2026-06-25 |
| Dr. Sudarshan Hebbar | Insider | 186.025 | 1,18% | US$ 177,82k | 2026-06-25 |
| Jane Street Group, LLC | Institution | 178.515 | 1,13% | US$ 170,64k | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 169.110 | 1,07% | US$ 161,65k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 128.075 | 0,81% | US$ 122,43k | 2026-03-31 |
| 180 Wealth Advisors, LLC | Institution | 126.500 | 0,80% | US$ 120,92k | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 123.382 | 0,78% | US$ 117,94k | 2026-03-31 |
| Sanderling Ventures Vii (Canada), L.P. | Institution | 114.260 | 0,72% | US$ 109,22k | 2025-03-31 |
| Dr. Frederic Guerard | Insider | 90.727 | 0,57% | US$ 86,73k | 2026-03-31 |
| Meritage Portfolio Management, Inc. | Institution | 61.539 | 0,39% | US$ 58,83k | 2025-12-31 |
| Cambridge Investment Research Advisors, Inc. | Institution | 60.000 | 0,38% | US$ 57,35k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 45.829 | 0,29% | US$ 43,81k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 39.699 | 0,25% | US$ 37,95k | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 30.716 | 0,19% | US$ 29,36k | 2026-03-31 |
| GSA Capital Partners LLP | Institution | 23.777 | 0,15% | US$ 22,73k | 2026-03-31 |
| Virtu Financial, Inc. | Institution | 17.895 | 0,11% | US$ 17,11k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 17.073 | 0,11% | US$ 16,32k | 2026-03-31 |
| Tritonpoint Partners, LLC | Institution | 15.119 | 0,10% | US$ 14,45k | 2026-03-31 |
| Simplex Trading, LLC | Institution | 12.816 | 0,08% | US$ 12,25k | 2026-03-31 |
| Ground Swell Capital, LLC | Institution | 12.307 | 0,08% | US$ 11,76k | 2026-03-31 |
| Sound View Wealth Advisors Group, LLC | Institution | 10.000 | 0,06% | US$ 9,56k | 2026-03-31 |
| FMR LLC | Institution | 9.698 | 0,06% | US$ 9,27k | 2026-04-30 |
| Rockefeller & Co. LLC | Institution | 5.000 | 0,03% | US$ 4,78k | 2026-03-31 |
| Tower Research Capital Europe Limited | Institution | 2.022 | 0,01% | US$ 1,93k | 2026-03-31 |
| UBS Asset Management AG | Institution | 17 | 0,00% | US$ 16,25 | 2026-03-31 |
| Bank of America Corporation | Institution | 0 | 0,00% | - | 2026-03-31 |
| Envestnet Asset Management, Inc. | Institution | 0 | 0,00% | - | 2026-03-31 |
| Millennium Management LLC | Institution | 0 | 0,00% | - | 2026-03-31 |
| Summit Equities, Inc. | Institution | 0 | 0,00% | - | 2026-03-31 |
| J. Goldman & Co., L.P. | Institution | 0 | 0,00% | - | 2026-03-31 |
| PVG Asset Management Corp | Institution | 0 | 0,00% | - | 2026-03-31 |