| BlackRock, Inc. | Institution | 12.795.277 | 6,58% | US$ 37,36M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 7.145.550 | 3,67% | US$ 20,87M | 2026-03-31 |
| Viking Global Investors LP | Institution | 6.700.000 | 3,45% | US$ 19,56M | 2026-04-24 |
| RA Capital Management, L.P. | Institution | 6.500.000 | 3,34% | US$ 18,98M | 2026-04-24 |
| RA Capital Healthcare Fund, L.P. | Institution | 6.500.000 | 3,34% | US$ 18,98M | 2026-04-24 |
| Vanguard Capital Management, LLC | Institution | 5.658.049 | 2,91% | US$ 16,52M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 5.382.002 | 2,77% | US$ 15,72M | 2026-03-31 |
| TCG Crossover Fund III, L.P. | Institution | 5.000.000 | 2,57% | US$ 14,60M | 2026-04-24 |
| Marshall Wace LLP | Institution | 4.017.901 | 2,07% | US$ 11,73M | 2026-03-31 |
| Millennium Management LLC | Institution | 3.258.191 | 1,68% | US$ 9,51M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 3.107.096 | 1,60% | US$ 9,07M | 2026-03-31 |
| Alyeska Investment Group, L.P. | Institution | 2.644.600 | 1,36% | US$ 7,72M | 2026-03-31 |
| Deep Track Special Opportunities Fund, Lp | Institution | 2.588.963 | 1,33% | US$ 7,56M | 2026-04-23 |
| Two Sigma Investments, LP | Institution | 2.478.900 | 1,27% | US$ 7,24M | 2026-03-31 |
| Teachers Insurance and Annuity Association-College Retirement Equities Fund | Institution | 2.326.342 | 1,20% | US$ 6,79M | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 1.325.956 | 0,68% | US$ 3,87M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 1.185.705 | 0,61% | US$ 3,46M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 1.045.926 | 0,54% | US$ 3,05M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 996.721 | 0,51% | US$ 2,91M | 2026-03-31 |
| UBS Asset Management AG | Institution | 908.922 | 0,47% | US$ 2,65M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 869.318 | 0,45% | US$ 2,54M | 2026-03-31 |
| D. E. Shaw & Co., L.P. | Institution | 727.001 | 0,37% | US$ 2,12M | 2026-03-31 |
| Morgan Stanley | Institution | 720.186 | 0,37% | US$ 2,10M | 2026-03-31 |
| FMR LLC | Institution | 673.922 | 0,35% | US$ 1,97M | 2026-03-31 |
| Schroder Investment Management Limited | Institution | 667.837 | 0,34% | US$ 1,95M | 2026-03-31 |
| Tang Capital Management, LLC | Institution | 666.022 | 0,34% | US$ 1,94M | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 665.289 | 0,34% | US$ 1,94M | 2026-03-31 |
| Bank of America Corporation | Institution | 570.203 | 0,29% | US$ 1,66M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 448.873 | 0,23% | US$ 1,31M | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 435.078 | 0,22% | US$ 1,27M | 2026-03-31 |
| Dr. Vipin Garg | Insider | 424.519 | 0,22% | US$ 1,24M | 2026-01-31 |
| BNY Asset Management | Institution | 413.503 | 0,21% | US$ 1,21M | 2026-03-31 |