By Sara Sjolin, MarketWatch

LONDON (MarketWatch) -- European stock markets slid from multiyear highs on Wednesday, as investors stayed cautious ahead of comments from U.S. Federal Reserve Chairman Ben Bernanke.

The Stoxx Europe 600 index lost 0.5% to 308.49, retreating from the highest closing level since June 2008, reached on Tuesday.

Among the biggest decliners, shares of Kazakhmys PLC dropped 4.8%, after UBS cut the miner to neutral from buy.

Shares of Britvic PLC surged 12%, after the beverage firm said adjusted earnings per share rose 48% for the 28 weeks to April 14, while increasing dividends 1.9% to 5.4 pence (82 cents).

European investors were hesitant to make any major moves, ahead of events in the U.S. that could provide some clarity on if and how the Fed chooses to taper its $85-billion-a-month bond-purchase program. At 3 p.m. London time, 10 a.m. Eastern, Bernanke will testify before the Joint Economic Committee of Congress, his first testimony there since late February.

After the European market close, the central bank will release minutes from its April 30-May 1 meeting, which may provide more insight into the Fed's stance on quantitative easing.

On Tuesday, two other voting members of the Federal Open Market Committee spoke, with St. Louis Fed President James Bullard saying there isn't a case for scaling down the pace of asset purchases as long as inflation is so low.

Separately, New York Fed President William Dudley said the uncertain economic outlook makes it difficult to tell if the next adjustment to the Fed's QE program will be up or down.

"Those looking for firm hints that the Fed is about to scale back on asset purchases were disappointed by both Bullard and Dudley (the latter notoriously dovish) last night," analysts at Danske Bank said in a note.

"Not least Dudley's comments suggest that neither Bernanke nor today's FOMC minutes will hint at an early QE exit. We continue to look for the Fed to start tapering its purchases in [the fourth quarter]," they added.

Back in Europe, minutes from the Bank of England's latest policy meeting showed the Monetary Policy Committee voted unanimously to keep interest rates unchanged at a record low 0.5%. Additionally, three out of the nine members voted in favor of increasing the bank's asset purchases by 25 billion pounds ($38 billion) to a total of GBP400 billion.

The pound (GBPUSD) moved lower after the release, trading at $1.5103, compared with around $1.5135 ahead of the report.

The U.K.'s FTSE 100 index traded slightly lower at 6,801.54, dropping after climbing to the highest closing level since December 1999 on Tuesday.

Shares of Lloyds Banking Group PLC (LYG) rose 2.2%, after the bank said it expects to meet its additional capital requirements without having to issue further equity or use contingent capital securities.

Germany's DAX 30 index dropped 0.1% to 8,465.66, putting it on track to break an 11-day winning streak and retreat from an all-time high.

France's CAC 40 index slipped 0.4% to 4,019.65. Shares of Lagardere SCA added 3.1%, after J.P. Morgan Cazenove lifted the stock to neutral from underweight.

Outside the major indexes, shares of Roche Holding AG gained 1.6%, after Citigroup lifted the drug maker to buy from neutral.

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