| Frazier Life Sciences Management, LP | Institution | 7.679.684 | 12,59% | 819,04M € | 2026-03-31 |
| Janus Henderson Group plc | Institution | 6.945.813 | 11,39% | 740,77M € | 2026-03-31 |
| BlackRock, Inc. | Institution | 3.846.530 | 6,31% | 410,23M € | 2026-03-31 |
| Frazier Life Sciences IX, L.P. | Institution | 3.566.912 | 5,85% | 380,41M € | 2026-02-17 |
| Frazier Life Sciences Public Fund, L.P. | Institution | 2.514.947 | 4,12% | 268,22M € | 2026-01-23 |
| Vanguard Capital Management, LLC | Institution | 2.414.776 | 3,96% | 257,54M € | 2026-03-31 |
| FMR LLC | Institution | 1.964.807 | 3,22% | 209,55M € | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.944.281 | 3,19% | 207,36M € | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 1.717.421 | 2,82% | 183,16M € | 2026-03-31 |
| BVF Partners L.P. | Institution | 1.584.727 | 2,60% | 169,01M € | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 1.432.083 | 2,35% | 152,73M € | 2026-03-31 |
| Eventide Asset Management, LLC | Institution | 1.408.871 | 2,31% | 150,26M € | 2026-03-31 |
| Wellington Management Group LLP | Institution | 1.334.809 | 2,19% | 142,36M € | 2026-03-31 |
| Novo Holdings A/S | Institution | 1.325.000 | 2,17% | 141,31M € | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.260.003 | 2,07% | 134,38M € | 2026-03-31 |
| Tang Capital Management, LLC | Institution | 1.236.027 | 2,03% | 131,82M € | 2026-03-31 |
| TCG Crossover Management, LLC | Institution | 1.062.049 | 1,74% | 113,27M € | 2026-03-31 |
| Citadel Advisors LLC | Institution | 1.052.048 | 1,73% | 112,20M € | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 911.419 | 1,49% | 97,20M € | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 811.294 | 1,33% | 86,52M € | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 774.841 | 1,27% | 82,64M € | 2026-03-31 |
| Biotechnology Value Fund L.P. | Institution | 772.595 | 1,27% | 82,40M € | 2025-09-30 |
| Capital Research and Management Company | Institution | 724.415 | 1,19% | 77,26M € | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 710.938 | 1,17% | 75,82M € | 2026-03-31 |
| Bank of America Corporation | Institution | 676.624 | 1,11% | 72,16M € | 2026-03-31 |
| ClearBridge Investments, LLC | Institution | 671.870 | 1,10% | 71,65M € | 2026-03-31 |
| Emerald Advisers, LLC | Institution | 647.662 | 1,06% | 69,07M € | 2026-03-31 |
| Paradigm Biocapital Advisors LP | Institution | 625.000 | 1,02% | 66,66M € | 2026-03-31 |
| Lord, Abbett & Co. LLC | Institution | 617.064 | 1,01% | 65,81M € | 2026-03-31 |
| Biotechnology Value Fund II, L.P. | Institution | 610.666 | 1,00% | 65,13M € | 2025-09-30 |
| Renaissance Technologies LLC | Institution | 582.085 | 0,95% | 62,08M € | 2026-03-31 |
| BNY Asset Management | Institution | 579.179 | 0,95% | 61,77M € | 2026-03-31 |
| Woodline Partners LP | Institution | 567.894 | 0,93% | 60,57M € | 2026-03-31 |
| UBS Asset Management AG | Institution | 561.623 | 0,92% | 59,90M € | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 547.306 | 0,90% | 58,37M € | 2026-03-31 |
| Frazier Life Sciences XI, L.P. | Institution | 544.954 | 0,89% | 58,12M € | 2026-01-23 |
| Balyasny Asset Management L.P. | Institution | 539.031 | 0,88% | 57,49M € | 2026-03-31 |