| Frazier Life Sciences Management, LP | Institution | 7.679.684 | 12,59% | 858,59M € | 2026-03-31 |
| Janus Henderson Group plc | Institution | 6.945.813 | 11,39% | 776,54M € | 2026-03-31 |
| BlackRock, Inc. | Institution | 3.846.530 | 6,31% | 430,04M € | 2026-03-31 |
| Frazier Life Sciences IX, L.P. | Institution | 3.566.912 | 5,85% | 398,78M € | 2026-02-17 |
| Frazier Life Sciences Public Fund, L.P. | Institution | 2.514.947 | 4,12% | 281,17M € | 2026-01-23 |
| Vanguard Capital Management, LLC | Institution | 2.414.776 | 3,96% | 269,97M € | 2026-03-31 |
| FMR LLC | Institution | 1.964.807 | 3,22% | 219,67M € | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.944.281 | 3,19% | 217,37M € | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 1.717.421 | 2,82% | 192,01M € | 2026-03-31 |
| BVF Partners L.P. | Institution | 1.584.727 | 2,60% | 177,17M € | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 1.432.083 | 2,35% | 160,11M € | 2026-03-31 |
| Eventide Asset Management, LLC | Institution | 1.408.871 | 2,31% | 157,51M € | 2026-03-31 |
| Wellington Management Group LLP | Institution | 1.334.809 | 2,19% | 149,23M € | 2026-03-31 |
| Novo Holdings A/S | Institution | 1.325.000 | 2,17% | 148,14M € | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.260.003 | 2,07% | 140,87M € | 2026-03-31 |
| Tang Capital Management, LLC | Institution | 1.236.027 | 2,03% | 138,19M € | 2026-03-31 |
| TCG Crossover Management, LLC | Institution | 1.062.049 | 1,74% | 118,74M € | 2026-03-31 |
| Citadel Advisors LLC | Institution | 1.052.048 | 1,73% | 117,62M € | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 911.419 | 1,49% | 101,90M € | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 811.294 | 1,33% | 90,70M € | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 774.841 | 1,27% | 86,63M € | 2026-03-31 |
| Biotechnology Value Fund L.P. | Institution | 772.595 | 1,27% | 86,38M € | 2025-09-30 |
| Capital Research and Management Company | Institution | 724.415 | 1,19% | 80,99M € | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 710.938 | 1,17% | 79,48M € | 2026-03-31 |
| Bank of America Corporation | Institution | 676.624 | 1,11% | 75,65M € | 2026-03-31 |
| ClearBridge Investments, LLC | Institution | 671.870 | 1,10% | 75,12M € | 2026-03-31 |
| Emerald Advisers, LLC | Institution | 647.662 | 1,06% | 72,41M € | 2026-03-31 |
| Paradigm Biocapital Advisors LP | Institution | 625.000 | 1,02% | 69,88M € | 2026-03-31 |
| Lord, Abbett & Co. LLC | Institution | 617.064 | 1,01% | 68,99M € | 2026-03-31 |
| Biotechnology Value Fund II, L.P. | Institution | 610.666 | 1,00% | 68,27M € | 2025-09-30 |
| Renaissance Technologies LLC | Institution | 582.085 | 0,95% | 65,08M € | 2026-03-31 |
| BNY Asset Management | Institution | 579.179 | 0,95% | 64,75M € | 2026-03-31 |
| Woodline Partners LP | Institution | 567.894 | 0,93% | 63,49M € | 2026-03-31 |
| UBS Asset Management AG | Institution | 561.623 | 0,92% | 62,79M € | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 547.306 | 0,90% | 61,19M € | 2026-03-31 |
| Frazier Life Sciences XI, L.P. | Institution | 544.954 | 0,89% | 60,93M € | 2026-01-23 |
| Balyasny Asset Management L.P. | Institution | 539.031 | 0,88% | 60,26M € | 2026-03-31 |