Helping formulators develop innovative therapies for a
range of skin conditions while addressing evolving regulatory
compliance requirements further demonstrates DuPont's support for
good health and wellbeing
WILMINGTON, Del., April 13,
2023 /PRNewswire/ -- DuPont (NYSE: DD) today
announced the introduction of new low-cyclosiloxane silicone
elastomer blends and silicone resin blends in response to growing
consumer desires for products that address a range of troubling
skin conditions. These new topical excipient blends also address
the market's need to comply with evolving REACH regulatory
compliance demands and to support the shared commitment of DuPont
and its customers to the United Nations Sustainable Development
Goals (UN SDGs), particularly UNSDG No. 3 – Good Health and Well
Being – which calls for protecting human health and well-being for
all people at all ages.
![New developments in low-cyclosiloxanes silicone elastomer blends and silicone resin blends from DuPont™ Liveo™ Healthcare Solutions have the potential to help formulators develop innovative therapies for a range of troubling skin conditions, improve patient compliance and meet evolving regulatory compliance requirements. New developments in low-cyclosiloxanes silicone elastomer blends and silicone resin blends from DuPont™ Liveo™ Healthcare Solutions have the potential to help formulators develop innovative therapies for a range of troubling skin conditions, improve patient compliance and meet evolving regulatory compliance requirements.](https://mma.prnewswire.com/media/2050930/DuPont_Liveo.jpg)
"Over-the-counter topical and medical products to address scars,
actinic keratosis, atopic dermatitis, psoriasis and other skin
conditions are proliferating to meet consumer desires to feel good
at every age without compromising skin protection and drug delivery
efficiency," said DuPont™ Liveo™ Healthcare
Solutions EMEA Regional Marketing Leader Michele Vigliotti. "Meanwhile, regulations on
consumer healthcare products continue to evolve to ensure safety
and minimize public risk."
In response, DuPont™ Liveo™ has developed
four new low-cyclosiloxane silicone topical excipient blends. These
products are designed to help customers meet the substance of very
high concern (SVHC) threshold for concerned cyclosiloxanes –
below 0.1% – proposed by REACH regulation (EC) No.
1907/2006.
The new DuPont™ Liveo™ silicone
elastomer blends are:
- Liveo™ TE-9320 Silicone Elastomer Blend – a
blend of silicone elastomer network swollen in a Dimethicone
volatile carrier (ref. INCI names Dimethicone and Dimethicone
Crosspolymer) – is a non-occlusive rheology modifier with a skin
feel that is characterized by smoothness with a light, silky,
non-greasy feel. It contains less than 0.1% D4, D5 and D6.
- Liveo™ TE-9330 Silicone Elastomer Blend
– a blend of silicone elastomer network swollen in a
Dimethicone non-volatile carrier (ref. INCI names Dimethicone and
Dimethicone Crosspolymer) – is a non-occlusive thickening agent for
anhydrous and water-in-oil emulsions. It delivers a smooth, silky
feel and contains less than 0.1% D4, D5 and D6.
Potential uses for silicone elastomer blends
include topical drug delivery formulations for prescription
and over-the-counter products that may improve patient compliance
due to their unique sensory feel, including creams for conditions
such as atopic dermatitis, psoriasis, and scar and pain management,
as well as creams and gels that offer a mattifying effect for acne
applications. Silicone elastomer blend technologies also are known
for their effectiveness in support of drug release or drug
permeation in topical semi-solid formulations thereby providing
options to formulators.
The new DuPont™ Liveo™ silicone resin
blends are:
- Liveo™ TE-9720 Resin Blend – a blend of
silicone resin solubilized in a 100
cSt Dimethicone non-volatile carrier (ref. INCI names
Dimethicone and Trimethylsiloxysilicate) – exhibits film-forming
behavior and delivers a long-lasting film that is resistant to
water wash-off.
- In development: Liveo™ TE-9721 Resin Blend –
a blend of silicone resin solubilized in a Caprylyl Methicone
volatile carrier (ref. INCI names Caprylyl Methicone and
Trimethylsiloxysilicate) – exhibits film-forming behavior and
delivers a long-lasting film that is resistant to water wash-off.
Additionally, it offers good compatibility with a wide range of
formulation ingredients.
Liveo™ silicone resin blends can be incorporated
easily into many product forms, including creams for skin barrier
applications, sprays that offer ease of application and protect the
skin, and gels for novel product forms in challenging skin
conditions. Target indications include skin barriers and protective
films for ostomy care; liquid bandages, skin barriers and scar
management for wound care; UV protection and sunscreens for skin
care; and drug delivery therapy for acne, actinic keratosis,
antifungal and pain management in dermal care.
"DuPont serves a broad spectrum of consumer and medical topical
healthcare applications, from over-the-counter to prescription, "
Vigliotti said. "Whether customers are looking for technological
expertise, regulatory support, or a broad selection of high-quality
topical excipients that are easy to process and
patient-friendly, we are here to support them."
Liveo™ topical silicone excipients include
silicone-based materials that allow formulators to develop
innovative solutions for the efficient delivery of active
pharmaceutical ingredients (APIs) in topical forms like creams,
lotions, gels, ointments, sprays or sticks. The excipients support
unique and aesthetically appealing formulations, making
pharmaceutical finished dosage forms easier to apply and more
pleasant to use – without compromising drug delivery efficiency –
thereby helping to increase patient compliance. Learn more about
Liveo™ at liveo.dupont.com.
Liveo™ distributor partner Quimica San Diego is
showcasing DuPont's new developments in low-cyclosiloxanes silicone
elastomer blends and silicone resin blends at ExpoFarma
2023 April 19 through 21 from 2 to 9 p.m. at booth
1216 at the World Trade Center in Mexico
City, Mexico.
About DuPont™ Liveo™ Healthcare
Solutions
DuPont™ Liveo™ is a globally
recognized leader in technology for a broad range of innovations in
medical devices, biopharmaceutical processing and pharmaceutical
solutions. DuPont high-performance materials help create safer
healthcare environments and protect the health of patients and
healthcare providers worldwide. We help enable smarter healthcare
and positive patient outcomes. More information can be found at
liveo.dupont.com.
About DuPont Electronics & Industrial
DuPont
Electronics & Industrial is a global supplier of new
technologies and performance materials serving the semiconductor,
circuit board, display, digital and flexographic printing,
healthcare, aerospace, industrial, and transportation industries.
From advanced technology centers worldwide, teams of talented
research scientists and application experts work closely with
customers, providing solutions, products and technical service to
enable next-generation technologies.
About DuPont
DuPont (NYSE: DD) is a global innovation
leader with technology-based materials and solutions that help
transform industries and everyday life. Our employees apply diverse
science and expertise to help customers advance their best ideas
and deliver essential innovations in key markets including
electronics, transportation, construction, water, healthcare and
worker safety. More information about the company, its businesses
and solutions can be found at www.dupont.com. Investors can access
information included on the Investor Relations section of the
website at investors.dupont.com.
DuPont™, the DuPont Oval Logo, and all trademarks and service
marks denoted with ™, SM or ® are owned by
affiliates of DuPont de Nemours, Inc. unless otherwise noted.
View original content to download
multimedia:https://www.prnewswire.com/news-releases/dupont-liveo-healthcare-solutions-introduces-new-developments-in-low-cyclic-silicone-elastomer-blends-and-silicone-resin-blends-for-topical-applications-301793716.html
SOURCE DuPont