| TCG Crossover Management, LLC | Institution | 5.673.078 | 10,47% | US$ 81,24M | 2026-03-31 |
| Forbion Capital Partners B.V. | Institution | 4.117.354 | 7,60% | US$ 58,96M | 2026-03-31 |
| Forbion Growth Opportunities Fund III Cooperatief U.A. | Institution | 3.617.354 | 6,68% | US$ 51,80M | 2025-12-23 |
| VR Management, LLC | Institution | 3.041.719 | 5,61% | US$ 43,56M | 2026-03-31 |
| TCG Crossover Fund III, L.P. | Institution | 2.836.539 | 5,23% | US$ 40,62M | 2026-03-30 |
| TCG Crossover Fund II, L.P. | Institution | 2.836.539 | 5,23% | US$ 40,62M | 2026-03-30 |
| RA Capital Management, L.P. | Institution | 2.567.245 | 4,74% | US$ 36,76M | 2026-04-20 |
| RA Capital Healthcare Fund, L.P. | Institution | 2.567.245 | 4,74% | US$ 36,76M | 2026-04-20 |
| Frazier Life Sciences Management, LP | Institution | 2.543.939 | 4,69% | US$ 36,43M | 2026-03-31 |
| Venrock Healthcare Capital Partners EG, L.P. | Institution | 2.335.474 | 4,31% | US$ 33,44M | 2026-03-31 |
| Frazier Life Sciences Public Fund, L.P. | Institution | 2.258.001 | 4,17% | US$ 32,33M | 2025-12-18 |
| Qiming Weichuang Venture Capital Management (Shanghai) Company Limited | Institution | 1.999.939 | 3,69% | US$ 28,64M | 2026-03-31 |
| Caligan Partners, LP | Institution | 1.925.066 | 3,55% | US$ 27,57M | 2026-03-31 |
| Paradigm Biocapital Advisors LP | Institution | 1.750.000 | 3,23% | US$ 25,06M | 2026-03-31 |
| Great Point Partners, LLC | Institution | 1.750.000 | 3,23% | US$ 25,06M | 2026-03-31 |
| Paradigm BioCapital International Fund Ltd. | Institution | 1.546.061 | 2,85% | US$ 22,14M | 2025-11-11 |
| FMR LLC | Institution | 1.539.670 | 2,84% | US$ 22,05M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.433.280 | 2,65% | US$ 20,52M | 2026-03-31 |
| Mr. Reid Hoffman | Insider | 1.166.909 | 2,15% | US$ 16,71M | 2025-10-21 |
| Marshall Wace LLP | Institution | 1.153.276 | 2,13% | US$ 16,51M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.118.458 | 2,06% | US$ 16,02M | 2026-03-31 |
| Qiming Venture Partners VIII-HC, L.P. | Institution | 1.089.767 | 2,01% | US$ 15,61M | 2026-03-31 |
| Nextbio Capital Management Lp | Institution | 999.967 | 1,85% | US$ 14,32M | 2026-03-31 |
| Qiming Venture Partners VIII, L.P. | Institution | 910.172 | 1,68% | US$ 13,03M | 2026-03-31 |
| Biomedical Value Fund | Institution | 851.794 | 1,57% | US$ 12,20M | 2025-12-10 |
| BlackRock, Inc. | Institution | 794.759 | 1,47% | US$ 11,38M | 2026-03-31 |
| Logos Global Management, L.P. | Institution | 750.000 | 1,38% | US$ 10,74M | 2026-03-31 |
| Rosalind Advisors, Inc. | Institution | 700.000 | 1,29% | US$ 10,02M | 2026-03-31 |
| Venrock Healthcare Capital Partners III, L.P. | Institution | 642.031 | 1,18% | US$ 9,19M | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 555.702 | 1,03% | US$ 7,96M | 2026-03-31 |
| UBS Asset Management AG | Institution | 488.368 | 0,90% | US$ 6,99M | 2026-03-31 |
| Braidwell LP | Institution | 466.774 | 0,86% | US$ 6,68M | 2026-03-31 |
| Biomedical Offshore Value Fund, LTD. | Institution | 382.692 | 0,71% | US$ 5,48M | 2025-12-10 |
| Geode Capital Management, LLC | Institution | 342.573 | 0,63% | US$ 4,91M | 2026-03-31 |
| Clearline Capital LP | Institution | 326.168 | 0,60% | US$ 4,67M | 2026-03-31 |
| Sphera Funds Management Ltd | Institution | 321.917 | 0,59% | US$ 4,61M | 2026-03-31 |
| Laurion Capital Management LP | Institution | 318.670 | 0,59% | US$ 4,56M | 2026-03-31 |
| Frazier Life Sciences XII, L.P. | Institution | 264.824 | 0,49% | US$ 3,79M | 2025-12-18 |
| The Goldman Sachs Group, Inc. | Institution | 261.891 | 0,48% | US$ 3,75M | 2026-03-31 |
| Propel Bio Management, LLC | Institution | 261.033 | 0,48% | US$ 3,74M | 2026-03-31 |
| Millennium Management LLC | Institution | 258.587 | 0,48% | US$ 3,70M | 2026-03-31 |
| Susquehanna International Group, LLP | Institution | 232.608 | 0,43% | US$ 3,33M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 185.511 | 0,34% | US$ 2,66M | 2026-03-31 |
| Leap Investments LP | Institution | 172.800 | 0,32% | US$ 2,47M | 2026-03-31 |
| 5AM Ventures VI, L.P. | Institution | 159.732 | 0,29% | US$ 2,29M | 2025-07-08 |