| OrbiMed Advisors LLC | Institution | 5.693.589 | 10,46% | US$ 41,45M | 2026-03-31 |
| Orbimed Private Investments VIII, LP | Institution | 4.554.873 | 8,37% | US$ 33,16M | 2024-10-15 |
| BlackRock, Inc. | Institution | 3.370.689 | 6,19% | US$ 24,54M | 2026-03-31 |
| Decheng Capital Global Life Sciences Fund IV, L.P. | Institution | 3.085.293 | 5,67% | US$ 22,46M | 2024-12-31 |
| Decheng Capital LLC | Institution | 2.724.868 | 5,01% | US$ 19,84M | 2026-03-31 |
| HBM Healthcare Investments AG | Institution | 2.195.111 | 4,03% | US$ 15,98M | 2025-09-30 |
| Samsara Biocapital, L.P. | Institution | 2.067.146 | 3,80% | US$ 15,05M | 2024-10-11 |
| Omega Fund VII, L.P. | Institution | 2.036.293 | 3,74% | US$ 14,82M | 2024-10-11 |
| Vanguard Capital Management, LLC | Institution | 1.873.574 | 3,44% | US$ 13,64M | 2026-03-31 |
| Venrock Healthcare Capital Partners EG, L.P. | Institution | 1.361.463 | 2,50% | US$ 9,91M | 2024-10-11 |
| Orbimed Israel Partners II, L.P. | Institution | 1.138.716 | 2,09% | US$ 8,29M | 2024-10-15 |
| Y-Intercept (Hong Kong) Limited | Institution | 1.000.631 | 1,84% | US$ 7,28M | 2026-03-31 |
| Federated Hermes, Inc. | Institution | 979.758 | 1,80% | US$ 7,13M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 950.617 | 1,75% | US$ 6,92M | 2026-03-31 |
| Millennium Management LLC | Institution | 937.323 | 1,72% | US$ 6,82M | 2026-03-31 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | Institution | 894.733 | 1,64% | US$ 6,51M | 2024-10-15 |
| SEB Funds AB | Institution | 878.473 | 1,61% | US$ 6,40M | 2026-03-31 |
| Bain Capital Life Sciences Investors, LLC | Institution | 867.211 | 1,59% | US$ 6,31M | 2026-03-31 |
| D. E. Shaw & Co., L.P. | Institution | 820.480 | 1,51% | US$ 5,97M | 2026-03-31 |
| Parkman Healthcare Partners LLC | Institution | 786.783 | 1,45% | US$ 5,73M | 2026-03-31 |
| Samsara BioCapital LLC | Institution | 736.047 | 1,35% | US$ 5,36M | 2026-03-31 |
| Venrock Healthcare Capital Partners III, L.P. | Institution | 417.125 | 0,77% | US$ 3,04M | 2024-10-11 |
| Nantahala Capital Management, LLC | Institution | 400.000 | 0,74% | US$ 2,91M | 2026-03-31 |
| JPMorgan Chase & Co. | Institution | 384.349 | 0,71% | US$ 2,80M | 2026-03-31 |
| Altshuler Shaham Ltd. | Institution | 380.061 | 0,70% | US$ 2,77M | 2026-03-31 |
| Sphera Funds Management Ltd | Institution | 358.000 | 0,66% | US$ 2,61M | 2026-03-31 |
| Leap Investments LP | Institution | 319.400 | 0,59% | US$ 2,33M | 2026-03-31 |
| Alyeska Investment Group, L.P. | Institution | 298.329 | 0,55% | US$ 2,17M | 2026-03-31 |
| Propel Bio Management, LLC | Institution | 263.986 | 0,49% | US$ 1,92M | 2026-03-31 |
| Prosight Management, LP | Institution | 241.123 | 0,44% | US$ 1,76M | 2026-03-31 |
| XTX Markets Limited | Institution | 209.277 | 0,38% | US$ 1,52M | 2026-03-31 |
| Decheng Capital Global Healthcare Fund (Master), LP | Institution | 200.000 | 0,37% | US$ 1,46M | 2024-12-31 |