| FMR LLC | Institution | 18.633.198 | 14,68% | US$ 665,76M | 2026-03-31 |
| ARK Investment Management LLC | Institution | 11.717.317 | 9,23% | US$ 418,66M | 2026-03-31 |
| BlackRock, Inc. | Institution | 10.079.244 | 7,94% | US$ 360,13M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 6.912.936 | 5,45% | US$ 247,00M | 2026-03-31 |
| Quantinno Capital Management LP | Institution | 5.411.761 | 4,26% | US$ 193,36M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 5.269.586 | 4,15% | US$ 188,28M | 2026-03-31 |
| Amova Asset Management Co., Ltd. | Institution | 5.110.214 | 4,03% | US$ 182,59M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 2.904.228 | 2,29% | US$ 103,77M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 2.838.803 | 2,24% | US$ 101,43M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 2.588.795 | 2,04% | US$ 92,50M | 2026-03-31 |
| AQR Capital Management, LLC | Institution | 2.419.446 | 1,91% | US$ 86,45M | 2026-03-31 |
| Jacobs Levy Equity Management Inc | Institution | 2.283.424 | 1,80% | US$ 81,59M | 2026-03-31 |
| Casdin Capital, LLC | Institution | 2.275.000 | 1,79% | US$ 81,29M | 2026-03-31 |
| Millennium Management LLC | Institution | 2.068.414 | 1,63% | US$ 73,90M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 2.042.950 | 1,61% | US$ 72,99M | 2026-03-31 |
| Capital Research and Management Company | Institution | 1.452.300 | 1,14% | US$ 51,89M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 1.442.597 | 1,14% | US$ 51,54M | 2026-03-31 |
| Eaton Vance Management | Institution | 1.407.772 | 1,11% | US$ 50,30M | 2026-03-31 |
| Goldman Sachs Asset Management, L.P. | Institution | 1.132.997 | 0,89% | US$ 40,48M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 1.127.056 | 0,89% | US$ 40,27M | 2026-03-31 |
| Morgan Stanley | Institution | 1.092.786 | 0,86% | US$ 39,05M | 2026-03-31 |
| Blue Water Life Science Advisors, LP | Institution | 1.090.000 | 0,86% | US$ 38,95M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 1.048.005 | 0,83% | US$ 37,45M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 1.008.739 | 0,79% | US$ 36,04M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 989.522 | 0,78% | US$ 35,36M | 2026-03-31 |
| Connor, Clark & Lunn Investment Management Ltd. | Institution | 938.408 | 0,74% | US$ 33,53M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 778.906 | 0,61% | US$ 27,83M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 743.734 | 0,59% | US$ 26,57M | 2026-03-31 |
| IEQ Capital, LLC | Institution | 700.684 | 0,55% | US$ 25,04M | 2026-03-31 |