| Baker Bros. Advisors LP | Institution | 5.072.730 | 14,08% | US$ 38,50M | 2026-03-31 |
| Baker Brothers Life Sciences, L.P. | Institution | 4.691.392 | 13,02% | US$ 35,61M | 2025-11-20 |
| 5AM Venture Management, LLC | Institution | 4.056.379 | 11,26% | US$ 30,79M | 2026-03-31 |
| 5AM Ventures V, L.P. | Institution | 2.963.066 | 8,22% | US$ 22,49M | 2025-11-14 |
| BlackRock, Inc. | Institution | 2.358.793 | 6,55% | US$ 17,90M | 2026-03-31 |
| TCG Crossover Management, LLC | Institution | 2.287.500 | 6,35% | US$ 17,36M | 2026-03-31 |
| MPM Bioventures 2018, L.P. | Institution | 2.150.236 | 5,97% | US$ 16,32M | 2024-12-11 |
| MPM Bioventures 2014, L.P. | Institution | 2.122.055 | 5,89% | US$ 16,11M | 2024-12-11 |
| The Column Group, LLC | Institution | 1.917.344 | 5,32% | US$ 14,55M | 2025-11-19 |
| TCG Crossover Fund I, L.P. | Institution | 1.917.344 | 5,32% | US$ 14,55M | 2025-11-19 |
| Janus Henderson Biotech Innovation Master Fund Limited | Institution | 1.884.826 | 5,23% | US$ 14,31M | 2025-03-31 |
| MRL Ventures Fund LLC | Institution | 1.739.768 | 4,83% | US$ 13,20M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.256.013 | 3,49% | US$ 9,53M | 2026-03-31 |
| 5AM Opportunities I, L.P. | Institution | 1.093.313 | 3,03% | US$ 8,30M | 2025-11-14 |
| Wellington Management Group LLP | Institution | 1.034.782 | 2,87% | US$ 7,85M | 2026-03-31 |
| StepStone Group Inc. | Institution | 761.277 | 2,11% | US$ 5,78M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 667.347 | 1,85% | US$ 5,07M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 533.798 | 1,48% | US$ 4,05M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 526.043 | 1,46% | US$ 3,99M | 2026-03-31 |
| Millennium Management LLC | Institution | 519.356 | 1,44% | US$ 3,94M | 2026-03-31 |
| 667, L.P. | Institution | 381.338 | 1,06% | US$ 2,89M | 2025-11-20 |
| Jones Hill Capital LP | Institution | 374.010 | 1,04% | US$ 2,84M | 2026-03-31 |
| Jacobs Levy Equity Management Inc | Institution | 333.914 | 0,93% | US$ 2,53M | 2026-03-31 |
| Acadian Asset Management LLC | Institution | 333.169 | 0,92% | US$ 2,53M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 324.471 | 0,90% | US$ 2,46M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 234.992 | 0,65% | US$ 1,78M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 220.494 | 0,61% | US$ 1,67M | 2026-03-31 |
| Woodline Partners LP | Institution | 215.977 | 0,60% | US$ 1,64M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 215.018 | 0,60% | US$ 1,63M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 214.751 | 0,60% | US$ 1,63M | 2026-03-31 |
| Lynx1 Capital Management LP | Institution | 211.689 | 0,59% | US$ 1,61M | 2026-03-31 |
| Longaeva Partners L.P. | Institution | 204.978 | 0,57% | US$ 1,56M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 202.084 | 0,56% | US$ 1,53M | 2026-03-31 |
| BNP Paribas Financial Markets SNC | Institution | 181.148 | 0,50% | US$ 1,37M | 2026-03-31 |
| Teachers Insurance and Annuity Association-College Retirement Equities Fund | Institution | 174.118 | 0,48% | US$ 1,32M | 2026-03-31 |
| Nantahala Capital Management, LLC | Institution | 159.332 | 0,44% | US$ 1,21M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 156.861 | 0,44% | US$ 1,19M | 2026-03-31 |
| XTX Markets Limited | Institution | 129.562 | 0,36% | US$ 983,38k | 2026-03-31 |
| Dr. Peter Kim | Insider | 129.330 | 0,36% | US$ 981,61k | 2026-04-13 |