| OrbiMed Advisors LLC | Institution | 1.203.260 | 7,94% | US$ 975,84k | 2026-05-05 |
| Orbimed Private Investments VIII, LP | Institution | 1.203.260 | 7,94% | US$ 975,84k | 2026-05-05 |
| Ally Bridge Group | Institution | 786.236 | 5,19% | US$ 637,64k | 2026-05-01 |
| Ally Bridge MedAlpha Master Fund L.P. | Institution | 786.236 | 5,19% | US$ 637,64k | 2026-05-01 |
| Adage Capital Management, L.P. | Institution | 730.000 | 4,82% | US$ 592,03k | 2026-03-31 |
| Adage Capital Partners, L.P. | Institution | 730.000 | 4,82% | US$ 592,03k | 2025-12-31 |
| Ikarian Capital, LLC | Institution | 678.142 | 4,48% | US$ 549,97k | 2026-03-31 |
| Ikarian Healthcare Master Fund, L.P. | Institution | 678.142 | 4,48% | US$ 549,97k | 2025-12-31 |
| Squadron Capital Management Llc | Institution | 511.714 | 3,38% | US$ 415,00k | 2026-03-31 |
| Dauntless Investment Group, Llc | Institution | 416.998 | 2,75% | US$ 338,19k | 2026-03-31 |
| Boothbay Fund Management, LLC | Institution | 194.536 | 1,28% | US$ 157,77k | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 154.098 | 1,02% | US$ 124,97k | 2026-03-31 |
| Dr. Werner Cautreels | Insider | 96.348 | 0,64% | US$ 78,14k | 2026-05-01 |
| Dr. Nikolay Savchuk | Insider | 80.517 | 0,53% | US$ 65,30k | 2026-05-01 |
| Dr. Iain Dukes | Insider | 80.517 | 0,53% | US$ 65,30k | 2026-05-01 |
| Geode Capital Management, LLC | Institution | 77.103 | 0,51% | US$ 62,53k | 2026-03-31 |
| Palumbo Wealth Management LLC | Institution | 61.175 | 0,40% | US$ 49,61k | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 55.193 | 0,36% | US$ 44,76k | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 31.804 | 0,21% | US$ 25,79k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 25.802 | 0,17% | US$ 20,93k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 21.241 | 0,14% | US$ 17,23k | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 19.244 | 0,13% | US$ 15,61k | 2026-03-31 |
| Lynx1 Capital Management LP | Institution | 15.078 | 0,10% | US$ 12,23k | 2026-03-31 |
| BlackRock, Inc. | Institution | 9.956 | 0,07% | US$ 8,07k | 2026-03-31 |
| UBS Asset Management AG | Institution | 4.053 | 0,03% | US$ 3,29k | 2026-03-31 |
| Tower Research Capital Europe Limited | Institution | 3.964 | 0,03% | US$ 3,21k | 2026-03-31 |
| Morgan Stanley | Institution | 3.729 | 0,02% | US$ 3,02k | 2026-03-31 |
| Vanguard Global Advisers, LLC | Institution | 262 | 0,00% | US$ 212,48 | 2026-03-31 |
| SBI Holdings, Inc. | Institution | 128 | 0,00% | US$ 103,81 | 2026-03-31 |
| Strategic Advisers LLC | Institution | 23 | 0,00% | US$ 18,65 | 2026-03-31 |
| Cassaday & Company, Inc. | Institution | 11 | 0,00% | US$ 8,92 | 2026-03-31 |
| Royal Bank of Canada | Institution | 6 | 0,00% | US$ 4,87 | 2026-03-31 |
| Robinswood Financial LLC | Institution | 5 | 0,00% | US$ 4,06 | 2026-03-31 |
| Edward Jones Trust Company | Institution | 2 | 0,00% | US$ 1,62 | 2026-03-31 |
| Northwestern Mutual Wealth Management Company | Institution | 2 | 0,00% | US$ 1,62 | 2026-03-31 |
| Caitong International Asset Management Co., Limited | Institution | 2 | 0,00% | US$ 1,62 | 2026-03-31 |
| The Vanguard Group, Inc. | Institution | 0 | 0,00% | - | 2026-01-01 |
| Susquehanna International Group, LLP | Institution | 0 | 0,00% | - | 2026-03-31 |
| Perceptive Advisors LLC | Institution | 0 | 0,00% | - | 2026-03-31 |
| Perceptive Life Sciences Master Fund, Ltd. | Institution | 0 | 0,00% | - | 2026-03-31 |
| Citadel Advisors LLC | Institution | 0 | 0,00% | - | 2026-03-31 |
| XTX Markets Limited | Institution | 0 | 0,00% | - | 2026-03-31 |
| Seven Fleet Capital Management LP | Institution | 0 | 0,00% | - | 2026-03-31 |