| Third Rock Ventures, LLC | Institution | 7.268.315 | 15,20% | US$ 272,49M | 2026-05-11 |
| FMR LLC | Institution | 7.168.939 | 14,99% | US$ 268,76M | 2026-03-31 |
| Third Rock Ventures V, LP | Institution | 6.299.097 | 13,17% | US$ 236,15M | 2026-05-11 |
| Arch Venture Partners, L.P. | Institution | 3.728.738 | 7,80% | US$ 139,79M | 2026-03-31 |
| Capital Research and Management Company | Institution | 3.634.580 | 7,60% | US$ 136,26M | 2026-03-31 |
| Cormorant Asset Management, LP | Institution | 2.957.521 | 6,18% | US$ 110,88M | 2026-03-31 |
| BlackRock, Inc. | Institution | 2.505.955 | 5,24% | US$ 93,95M | 2026-03-31 |
| Sofinnova Investments, Inc. | Institution | 1.904.408 | 3,98% | US$ 71,40M | 2026-03-31 |
| Johnson & Johnson Innovation - JJDC, Inc. | Institution | 1.784.517 | 3,73% | US$ 66,90M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 1.680.576 | 3,51% | US$ 63,00M | 2026-03-31 |
| Polar Capital Holdings Plc | Institution | 1.642.461 | 3,43% | US$ 61,58M | 2026-03-31 |
| Baker Bros. Advisors LP | Institution | 1.547.090 | 3,23% | US$ 58,00M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 1.487.056 | 3,11% | US$ 55,75M | 2026-03-31 |
| Vestal Point Capital, LP | Institution | 1.436.229 | 3,00% | US$ 53,84M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.325.082 | 2,77% | US$ 49,68M | 2026-03-31 |
| Goldman Sachs Asset Management, L.P. | Institution | 1.261.675 | 2,64% | US$ 47,30M | 2026-03-31 |
| UBS Asset Management AG | Institution | 1.070.624 | 2,24% | US$ 40,14M | 2026-03-31 |
| Third Rock Ventures VI, L.P. | Institution | 969.218 | 2,03% | US$ 36,34M | 2026-05-11 |
| State Street Global Advisors, Inc. | Institution | 759.552 | 1,59% | US$ 28,48M | 2026-03-31 |
| AllianceBernstein L.P. | Institution | 727.843 | 1,52% | US$ 27,29M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 721.622 | 1,51% | US$ 27,05M | 2026-03-31 |
| Perceptive Advisors LLC | Institution | 673.923 | 1,41% | US$ 25,27M | 2026-03-31 |
| Mr. Abraham Ceesay | Insider | 658.705 | 1,38% | US$ 24,69M | 2026-02-18 |
| Artal Group S.A. | Institution | 641.469 | 1,34% | US$ 24,05M | 2026-03-31 |
| Dr. Steven Paul | Insider | 519.308 | 1,09% | US$ 19,47M | 2025-09-12 |
| Dr. David Bredt | Insider | 393.075 | 0,82% | US$ 14,74M | 2026-02-19 |
| Sio Capital Management, LLC | Institution | 366.809 | 0,77% | US$ 13,75M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 320.909 | 0,67% | US$ 12,03M | 2026-03-31 |
| Millennium Management LLC | Institution | 319.552 | 0,67% | US$ 11,98M | 2026-03-31 |
| Kennedy Capital Management LLC | Institution | 257.431 | 0,54% | US$ 9,65M | 2026-03-31 |
| Burkehill Global Management, LP | Institution | 250.000 | 0,52% | US$ 9,37M | 2026-03-31 |
| Mr. Swamy Yeleswaram | Insider | 246.426 | 0,52% | US$ 9,24M | 2026-04-17 |
| Charles Schwab Investment Management, Inc. | Institution | 239.917 | 0,50% | US$ 8,99M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 237.992 | 0,50% | US$ 8,92M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 224.498 | 0,47% | US$ 8,42M | 2026-03-31 |