| Third Rock Ventures, LLC | Institution | 7.249.743 | 15,16% | US$ 282,09M | 2026-05-26 |
| FMR LLC | Institution | 7.168.939 | 14,99% | US$ 278,94M | 2026-03-31 |
| Third Rock Ventures V, LP | Institution | 6.280.525 | 13,13% | US$ 244,38M | 2026-05-26 |
| Arch Venture Partners, L.P. | Institution | 3.728.738 | 7,80% | US$ 145,09M | 2026-03-31 |
| Capital Research and Management Company | Institution | 3.634.580 | 7,60% | US$ 141,42M | 2026-03-31 |
| Cormorant Asset Management, LP | Institution | 2.957.521 | 6,18% | US$ 115,08M | 2026-03-31 |
| BlackRock, Inc. | Institution | 2.505.955 | 5,24% | US$ 97,51M | 2026-03-31 |
| Sofinnova Investments, Inc. | Institution | 1.904.408 | 3,98% | US$ 74,10M | 2026-03-31 |
| Johnson & Johnson Innovation - JJDC, Inc. | Institution | 1.784.517 | 3,73% | US$ 69,44M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 1.680.576 | 3,51% | US$ 65,39M | 2026-03-31 |
| Polar Capital Holdings Plc | Institution | 1.642.461 | 3,43% | US$ 63,91M | 2026-03-31 |
| Baker Bros. Advisors LP | Institution | 1.547.090 | 3,23% | US$ 60,20M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 1.487.056 | 3,11% | US$ 57,86M | 2026-03-31 |
| Vestal Point Capital, LP | Institution | 1.436.229 | 3,00% | US$ 55,88M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.325.082 | 2,77% | US$ 51,56M | 2026-03-31 |
| Goldman Sachs Asset Management, L.P. | Institution | 1.261.675 | 2,64% | US$ 49,09M | 2026-03-31 |
| UBS Asset Management AG | Institution | 1.070.624 | 2,24% | US$ 41,66M | 2026-03-31 |
| Third Rock Ventures VI, L.P. | Institution | 969.218 | 2,03% | US$ 37,71M | 2026-05-26 |
| State Street Global Advisors, Inc. | Institution | 759.552 | 1,59% | US$ 29,55M | 2026-03-31 |
| AllianceBernstein L.P. | Institution | 727.843 | 1,52% | US$ 28,32M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 721.622 | 1,51% | US$ 28,08M | 2026-03-31 |
| Perceptive Advisors LLC | Institution | 673.923 | 1,41% | US$ 26,22M | 2026-03-31 |
| Artal Group S.A. | Institution | 641.469 | 1,34% | US$ 24,96M | 2026-03-31 |
| Sio Capital Management, LLC | Institution | 366.809 | 0,77% | US$ 14,27M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 320.909 | 0,67% | US$ 12,49M | 2026-03-31 |
| Millennium Management LLC | Institution | 319.552 | 0,67% | US$ 12,43M | 2026-03-31 |
| Kennedy Capital Management LLC | Institution | 257.431 | 0,54% | US$ 10,02M | 2026-03-31 |
| Burkehill Global Management, LP | Institution | 250.000 | 0,52% | US$ 9,73M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 239.917 | 0,50% | US$ 9,34M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 237.992 | 0,50% | US$ 9,26M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 224.498 | 0,47% | US$ 8,74M | 2026-03-31 |
| Ensign Peak Advisors, Inc. | Institution | 194.200 | 0,41% | US$ 7,56M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 189.253 | 0,40% | US$ 7,36M | 2026-03-31 |
| Candriam, Société En Commandite Par Actions | Institution | 185.925 | 0,39% | US$ 7,23M | 2026-03-31 |