| Frazier Life Sciences Management, LP | Institution | 12.466.489 | 15,63% | US$ 124,66M | 2026-03-31 |
| Medicxi Ventures (UK) LLP | Institution | 7.464.572 | 9,36% | US$ 74,65M | 2026-03-31 |
| Frazier Life Sciences IX, L.P. | Institution | 5.827.416 | 7,31% | US$ 58,27M | 2025-11-01 |
| Frazier Life Sciences Public Fund, L.P. | Institution | 5.323.356 | 6,67% | US$ 53,23M | 2025-11-01 |
| Invesco Ltd. | Institution | 4.317.426 | 5,41% | US$ 43,17M | 2026-03-31 |
| BlackRock, Inc. | Institution | 4.061.972 | 5,09% | US$ 40,62M | 2026-03-31 |
| Millennium Management LLC | Institution | 4.022.909 | 5,04% | US$ 40,23M | 2026-03-31 |
| Abingworth LLP | Institution | 3.496.808 | 4,38% | US$ 34,97M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 2.583.636 | 3,24% | US$ 25,84M | 2026-03-31 |
| Abingworth Bioventures 8 LP | Institution | 2.061.702 | 2,59% | US$ 20,62M | 2025-08-28 |
| New Enterprise Associates, Inc. | Institution | 1.960.169 | 2,46% | US$ 19,60M | 2026-03-31 |
| 683 Capital Management, LLC | Institution | 1.850.000 | 2,32% | US$ 18,50M | 2026-03-31 |
| Ensign Peak Advisors, Inc. | Institution | 1.627.806 | 2,04% | US$ 16,28M | 2026-03-31 |
| Catalys Pacific | Institution | 1.493.854 | 1,87% | US$ 14,94M | 2026-03-31 |
| Abingworth Bioventures VII LP | Institution | 1.435.106 | 1,80% | US$ 14,35M | 2025-08-28 |
| GW&K Investment Management, LLC | Institution | 1.421.109 | 1,78% | US$ 14,21M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.386.890 | 1,74% | US$ 13,87M | 2026-03-31 |
| Wasatch Advisors LP | Institution | 1.340.916 | 1,68% | US$ 13,41M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.328.045 | 1,67% | US$ 13,28M | 2026-03-31 |
| Integrated Core Strategies (US) LLC | Institution | 1.255.161 | 1,57% | US$ 12,55M | 2025-12-31 |
| Mr. David Socks | Insider | 1.220.756 | 1,53% | US$ 12,21M | 2025-04-07 |
| Nomura Investment Management Business Trust | Institution | 1.205.369 | 1,51% | US$ 12,05M | 2026-03-31 |
| Frazier Life Sciences Public Overage Fund, L.P. | Institution | 1.088.365 | 1,36% | US$ 10,88M | 2025-08-18 |
| Crestline Investors Inc. | Institution | 995.885 | 1,25% | US$ 9,96M | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 994.482 | 1,25% | US$ 9,94M | 2026-03-31 |
| Frazier Life Sciences XI, L.P. | Institution | 980.286 | 1,23% | US$ 9,80M | 2025-11-01 |
| Perceptive Advisors LLC | Institution | 925.000 | 1,16% | US$ 9,25M | 2026-03-31 |
| Marshall Wace LLP | Institution | 860.692 | 1,08% | US$ 8,61M | 2026-03-31 |
| Dr. Azmi Nabulsi | Insider | 794.995 | 1,00% | US$ 7,95M | 2026-03-23 |
| Vanguard Portfolio Management, LLC | Institution | 666.029 | 0,84% | US$ 6,66M | 2026-03-31 |
| EcoR1 Capital, LLC | Institution | 625.000 | 0,78% | US$ 6,25M | 2026-03-31 |
| Propel Bio Management, LLC | Institution | 578.886 | 0,73% | US$ 5,79M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 540.370 | 0,68% | US$ 5,40M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 482.136 | 0,60% | US$ 4,82M | 2026-03-31 |
| StepStone Group Inc. | Institution | 422.085 | 0,53% | US$ 4,22M | 2026-03-31 |
| UBS Asset Management AG | Institution | 416.159 | 0,52% | US$ 4,16M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 414.956 | 0,52% | US$ 4,15M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 409.015 | 0,51% | US$ 4,09M | 2026-03-31 |
| Ms. Terrie Curran | Insider | 389.860 | 0,49% | US$ 3,90M | 2026-03-23 |