| Soleus Capital Master Fund, L.P. | Institution | 12.484.876 | 9,70% | US$ 31,21M | 2024-12-31 |
| Mr. Glenn Nussdorf | Insider | 12.248.560 | 9,52% | US$ 30,62M | 2026-04-10 |
| Morgan Stanley | Institution | 11.564.739 | 8,99% | US$ 28,91M | 2026-03-31 |
| Soleus Capital Management, L.P. | Institution | 10.085.951 | 7,84% | US$ 25,21M | 2026-03-31 |
| BlackRock, Inc. | Institution | 4.899.751 | 3,81% | US$ 12,25M | 2026-03-31 |
| First Light Asset Management, LLC | Institution | 3.498.533 | 2,72% | US$ 8,75M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 2.900.816 | 2,25% | US$ 7,25M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 2.891.006 | 2,25% | US$ 7,23M | 2026-03-31 |
| D. E. Shaw & Co., L.P. | Institution | 2.297.974 | 1,79% | US$ 5,74M | 2026-03-31 |
| Assenagon Asset Management S.A. | Institution | 1.967.952 | 1,53% | US$ 4,92M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.783.964 | 1,39% | US$ 4,46M | 2026-03-31 |
| Deutsche Asset & Wealth Management | Institution | 1.705.681 | 1,33% | US$ 4,26M | 2026-03-31 |
| Acadian Asset Management LLC | Institution | 1.576.645 | 1,23% | US$ 3,94M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.525.108 | 1,19% | US$ 3,81M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 1.449.092 | 1,13% | US$ 3,62M | 2026-03-31 |
| Norges Bank Investment Management | Institution | 1.097.600 | 0,85% | US$ 2,74M | 2025-12-31 |
| Renaissance Technologies LLC | Institution | 1.068.538 | 0,83% | US$ 2,67M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 879.832 | 0,68% | US$ 2,20M | 2026-03-31 |
| AQR Capital Management, LLC | Institution | 868.905 | 0,68% | US$ 2,17M | 2026-03-31 |
| SG Americas Securities, LLC | Institution | 790.766 | 0,61% | US$ 1,98M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 554.428 | 0,43% | US$ 1,39M | 2026-03-31 |
| Sphera Funds Management Ltd | Institution | 550.000 | 0,43% | US$ 1,38M | 2026-03-31 |
| Bank of America Corporation | Institution | 548.262 | 0,43% | US$ 1,37M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 544.235 | 0,42% | US$ 1,36M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 498.452 | 0,39% | US$ 1,25M | 2026-03-31 |
| Los Angeles Capital Management LLC | Institution | 491.841 | 0,38% | US$ 1,23M | 2026-03-31 |
| State of Wisconsin Investment Board | Institution | 456.367 | 0,35% | US$ 1,14M | 2026-03-31 |
| Flax Pond Capital, LLC | Institution | 420.091 | 0,33% | US$ 1,05M | 2026-03-31 |
| Wealth Dimensions Group, Ltd. | Institution | 407.965 | 0,32% | US$ 1,02M | 2026-03-31 |
| FMR LLC | Institution | 375.815 | 0,29% | US$ 939,54k | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 355.081 | 0,28% | US$ 887,70k | 2026-03-31 |