| Catalyst4, Inc | Institution | 19.697.464 | 43,44% | US$ 597,82M | 2025-10-28 |
| Novo Holdings A/S | Institution | 3.686.622 | 8,13% | US$ 111,89M | 2026-03-31 |
| T. Rowe Price Group, Inc. | Institution | 3.250.266 | 7,17% | US$ 98,65M | 2026-03-31 |
| Forbion Growth Opportunities Fund III Cooperatief U.A. | Institution | 3.226.400 | 7,12% | US$ 97,92M | 2025-12-31 |
| Forbion Capital Partners B.V. | Institution | 3.226.400 | 7,12% | US$ 97,92M | 2026-03-31 |
| Pivotal BioVenture Partners LLC | Institution | 1.582.700 | 3,49% | US$ 48,03M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1.339.731 | 2,95% | US$ 40,66M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 1.133.385 | 2,50% | US$ 34,40M | 2026-03-31 |
| CHI Advisors LLC | Institution | 1.005.929 | 2,22% | US$ 30,53M | 2026-03-31 |
| 5AM Venture Management, LLC | Institution | 950.011 | 2,10% | US$ 28,83M | 2026-03-31 |
| Sanofi | Institution | 912.041 | 2,01% | US$ 27,68M | 2026-03-31 |
| Goldman Sachs Asset Management, L.P. | Institution | 861.488 | 1,90% | US$ 26,15M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 719.820 | 1,59% | US$ 21,85M | 2026-03-31 |
| Velan Capital Partners LP | Institution | 492.893 | 1,09% | US$ 14,96M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 481.201 | 1,06% | US$ 14,60M | 2026-03-31 |
| Artal Group S.A. | Institution | 450.000 | 0,99% | US$ 13,66M | 2026-03-31 |
| Vestal Point Capital, LP | Institution | 420.000 | 0,93% | US$ 12,75M | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 374.909 | 0,83% | US$ 11,38M | 2026-03-31 |
| Baker Bros. Advisors LP | Institution | 364.705 | 0,80% | US$ 11,07M | 2026-03-31 |
| Mr. Vishwas Setia | Insider | 356.256 | 0,79% | US$ 10,81M | 2026-05-06 |
| Dr. Erin Foff | Insider | 346.059 | 0,76% | US$ 10,50M | 2026-05-07 |
| State Street Global Advisors, Inc. | Institution | 339.116 | 0,75% | US$ 10,29M | 2026-03-31 |
| Freestone Grove Partners LP | Institution | 313.957 | 0,69% | US$ 9,53M | 2026-03-31 |
| AXA Investment Managers S.A. | Institution | 267.746 | 0,59% | US$ 8,13M | 2026-03-31 |
| RA Capital Management, L.P. | Institution | 248.294 | 0,55% | US$ 7,54M | 2026-03-31 |
| Dr. James Lillie | Insider | 242.729 | 0,54% | US$ 7,37M | 2026-05-07 |
| UBS Asset Management AG | Institution | 236.512 | 0,52% | US$ 7,18M | 2026-03-31 |
| Dr. Robert Malenka | Insider | 216.893 | 0,48% | US$ 6,58M | 2026-04-27 |
| Dr. Anatol Kreitzer | Insider | 211.190 | 0,47% | US$ 6,41M | 2026-04-27 |
| FMR LLC | Institution | 204.501 | 0,45% | US$ 6,21M | 2026-03-31 |
| Stanford Management Company | Institution | 199.231 | 0,44% | US$ 6,05M | 2026-03-31 |
| Superstring Capital Management LP | Institution | 192.139 | 0,42% | US$ 5,83M | 2026-03-31 |
| Dafna Capital Management, LLC | Institution | 171.006 | 0,38% | US$ 5,19M | 2026-03-31 |
| Mr. Kristopher Hanson | Insider | 162.331 | 0,36% | US$ 4,93M | 2026-05-11 |
| Charles Schwab Investment Management, Inc. | Institution | 161.146 | 0,36% | US$ 4,89M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 146.172 | 0,32% | US$ 4,44M | 2026-03-31 |
| Lazard Asset Management LLC | Institution | 142.016 | 0,31% | US$ 4,31M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 131.231 | 0,29% | US$ 3,98M | 2026-03-31 |
| Dr. Christopher Kroeger | Insider | 114.120 | 0,25% | US$ 3,46M | 2026-05-18 |
| Vanguard Portfolio Management, LLC | Institution | 112.604 | 0,25% | US$ 3,42M | 2026-03-31 |
| Tetragon Partners UK LLP | Institution | 112.115 | 0,25% | US$ 3,40M | 2026-03-31 |