| Frazier Life Sciences Management, LP | Institution | 6.652.013 | 13,98% | US$ 199,89M | 2026-03-31 |
| Frazier Life Sciences X, L.P. | Institution | 5.219.440 | 10,97% | US$ 156,84M | 2025-09-26 |
| OrbiMed Advisors LLC | Institution | 3.637.887 | 7,64% | US$ 109,32M | 2026-03-31 |
| New Enterprise Associates, Inc. | Institution | 3.614.486 | 7,59% | US$ 108,62M | 2026-03-31 |
| New Enterprise Associates 17, L.P. | Institution | 3.614.486 | 7,59% | US$ 108,62M | 2025-11-10 |
| Wellington Management Group LLP | Institution | 3.191.824 | 6,71% | US$ 95,91M | 2026-03-31 |
| Orbimed Private Investments VII, LP | Institution | 2.958.000 | 6,21% | US$ 88,89M | 2026-02-11 |
| BlackRock, Inc. | Institution | 2.941.406 | 6,18% | US$ 88,39M | 2026-03-31 |
| FMR LLC | Institution | 2.936.684 | 6,17% | US$ 88,25M | 2026-03-31 |
| Deep Track Capital, LP | Institution | 2.757.569 | 5,79% | US$ 82,86M | 2026-03-31 |
| Deep Track Biotechnology Master Fund, Ltd | Institution | 2.188.592 | 4,60% | US$ 65,77M | 2025-06-30 |
| Norwest Venture Partners XVI, LP. | Institution | 2.136.335 | 4,49% | US$ 64,20M | 2025-09-26 |
| NVP Associates, LLC | Institution | 2.136.335 | 4,49% | US$ 64,20M | 2026-03-31 |
| Wellington Biomedical Innovation Master Investors (Cayman) II L.P. | Institution | 2.017.394 | 4,24% | US$ 60,62M | 2025-09-30 |
| Polar Capital Holdings Plc | Institution | 1.622.186 | 3,41% | US$ 48,75M | 2026-03-31 |
| Braidwell LP | Institution | 1.492.467 | 3,14% | US$ 44,85M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.477.592 | 3,10% | US$ 44,40M | 2026-03-31 |
| Mr. Peter Hawryluk | Insider | 1.214.444 | 2,55% | US$ 36,49M | 2026-05-06 |
| Aaron Wealth Advisors LLC | Institution | 1.168.176 | 2,45% | US$ 35,10M | 2026-03-31 |
| Cormorant Asset Management, LP | Institution | 1.120.000 | 2,35% | US$ 33,66M | 2026-03-31 |
| Frazier Life Sciences Public Fund, L.P. | Institution | 1.103.920 | 2,32% | US$ 33,17M | 2025-09-26 |
| T. Rowe Price Group, Inc. | Institution | 1.029.007 | 2,16% | US$ 30,92M | 2026-03-31 |
| Driehaus Capital Management LLC | Institution | 1.018.212 | 2,14% | US$ 30,60M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 934.799 | 1,96% | US$ 28,09M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 932.833 | 1,96% | US$ 28,03M | 2026-03-31 |
| Woodline Partners LP | Institution | 900.063 | 1,89% | US$ 27,05M | 2026-03-31 |
| Eventide Asset Management, LLC | Institution | 890.000 | 1,87% | US$ 26,74M | 2026-03-31 |
| Caligan Partners, LP | Institution | 848.590 | 1,78% | US$ 25,50M | 2026-03-31 |
| Parkman Healthcare Partners LLC | Institution | 800.037 | 1,68% | US$ 24,04M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 787.208 | 1,65% | US$ 23,66M | 2026-03-31 |
| EcoR1 Capital, LLC | Institution | 777.000 | 1,63% | US$ 23,35M | 2026-03-31 |
| OrbiMed Genesis Master Fund, L.P. | Institution | 679.887 | 1,43% | US$ 20,43M | 2026-02-11 |
| Geode Capital Management, LLC | Institution | 670.385 | 1,41% | US$ 20,15M | 2026-03-31 |
| TCG Crossover Management, LLC | Institution | 650.000 | 1,37% | US$ 19,53M | 2026-03-31 |
| Millennium Management LLC | Institution | 564.415 | 1,19% | US$ 16,96M | 2026-03-31 |
| StemPoint Capital LP | Institution | 499.469 | 1,05% | US$ 15,01M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 425.546 | 0,89% | US$ 12,79M | 2026-03-31 |
| UBS Asset Management AG | Institution | 354.152 | 0,74% | US$ 10,64M | 2026-03-31 |
| Frazier Life Sciences Public Overage Fund, L.P. | Institution | 325.653 | 0,68% | US$ 9,79M | 2025-09-26 |
| Candriam, Société En Commandite Par Actions | Institution | 294.374 | 0,62% | US$ 8,85M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 293.295 | 0,62% | US$ 8,81M | 2026-03-31 |
| D. E. Shaw & Co., L.P. | Institution | 288.889 | 0,61% | US$ 8,68M | 2026-03-31 |