| RA Capital Management, L.P. | Institution | 4.178.823 | 13,33% | US$ 30,09M | 2026-03-31 |
| Alpha Wave Global, LP | Institution | 3.612.211 | 11,52% | US$ 26,01M | 2026-03-31 |
| FMR LLC | Institution | 3.597.742 | 11,47% | US$ 25,90M | 2026-03-31 |
| RA Capital Healthcare Fund, L.P. | Institution | 3.319.339 | 10,59% | US$ 23,90M | 2025-11-05 |
| Versant Venture Management, LLC | Institution | 2.656.888 | 8,47% | US$ 19,13M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1.976.823 | 6,30% | US$ 14,23M | 2026-03-31 |
| Squarepoint OPS LLC | Institution | 1.593.246 | 5,08% | US$ 11,47M | 2026-04-01 |
| Squarepoint Master Fund Limited | Institution | 1.590.333 | 5,07% | US$ 11,45M | 2026-04-01 |
| Paradigm BioCapital International Fund Ltd. | Institution | 1.254.521 | 4,00% | US$ 9,03M | 2025-03-20 |
| Aberdeen Group Plc | Institution | 1.156.161 | 3,69% | US$ 8,32M | 2026-03-31 |
| Franklin Resources, Inc. | Institution | 1.092.259 | 3,48% | US$ 7,86M | 2026-03-31 |
| Versant Venture Capital VI | Institution | 1.050.599 | 3,35% | US$ 7,56M | 2025-11-05 |
| Vanguard Capital Management, LLC | Institution | 1.041.188 | 3,32% | US$ 7,50M | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 1.017.751 | 3,25% | US$ 7,33M | 2026-03-31 |
| Millennium Management LLC | Institution | 869.257 | 2,77% | US$ 6,26M | 2026-03-31 |
| Versant Vantage II, L.P. | Institution | 842.162 | 2,69% | US$ 6,06M | 2025-11-05 |
| Versant Venture Capital VII, L.P. | Institution | 764.127 | 2,44% | US$ 5,50M | 2025-11-05 |
| C WorldWide Asset Management Fondsmaeglerselskab A/S | Institution | 700.000 | 2,23% | US$ 5,04M | 2026-03-31 |
| RA Capital Nexus Fund II, L.P. | Institution | 694.755 | 2,22% | US$ 5,00M | 2025-11-05 |
| Morgan Stanley | Institution | 639.076 | 2,04% | US$ 4,60M | 2026-03-31 |
| Mr. James McCollum | Insider | 631.099 | 2,01% | US$ 4,54M | 2026-04-14 |
| Geode Capital Management, LLC | Institution | 524.574 | 1,67% | US$ 3,78M | 2026-03-31 |
| CHI Advisors LLC | Institution | 506.722 | 1,62% | US$ 3,65M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 500.997 | 1,60% | US$ 3,61M | 2026-03-31 |
| PRIMECAP Management Company | Institution | 472.200 | 1,51% | US$ 3,40M | 2026-03-31 |
| Alyeska Investment Group, L.P. | Institution | 463.495 | 1,48% | US$ 3,34M | 2026-03-31 |
| Tang Capital Management, LLC | Institution | 451.114 | 1,44% | US$ 3,25M | 2026-03-31 |
| Medical Strategy GmbH | Institution | 411.347 | 1,31% | US$ 2,96M | 2025-12-31 |
| Merrill Lynch, Pierce, Fenner & Smith Incorporated | Institution | 405.819 | 1,29% | US$ 2,92M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 402.225 | 1,28% | US$ 2,90M | 2026-03-31 |
| Silvercrest Asset Management Group LLC | Institution | 283.206 | 0,90% | US$ 2,04M | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 257.460 | 0,82% | US$ 1,85M | 2026-03-31 |
| Discovery Capital Management, LLC | Institution | 241.300 | 0,77% | US$ 1,74M | 2026-03-31 |
| XTX Markets Limited | Institution | 221.037 | 0,70% | US$ 1,59M | 2026-03-31 |
| Trexquant Investment LP | Institution | 214.408 | 0,68% | US$ 1,54M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 185.624 | 0,59% | US$ 1,34M | 2026-03-31 |
| UBS Asset Management AG | Institution | 182.777 | 0,58% | US$ 1,32M | 2026-03-31 |