| Wellington Management Group LLP | Institution | 11.982.283 | 13,89% | US$ 393,50M | 2026-03-31 |
| Bain Capital Life Sciences Investors, LLC | Institution | 8.448.158 | 9,80% | US$ 277,44M | 2026-04-30 |
| KKR & Co. Inc. | Institution | 5.474.931 | 6,35% | US$ 179,80M | 2026-04-24 |
| FMR LLC | Institution | 5.396.363 | 6,26% | US$ 177,22M | 2026-03-31 |
| Baron Capital Group, Inc. | Institution | 3.827.531 | 4,44% | US$ 125,70M | 2026-03-31 |
| Mr. Lonnie Smith | Insider | 3.474.304 | 4,03% | US$ 114,10M | 2025-08-08 |
| Hadley Harbor Master Investors (Cayman) II L.P. | Institution | 3.388.522 | 3,93% | US$ 111,28M | 2025-08-08 |
| U.S. Venture Partners X, L.P. | Institution | 3.171.062 | 3,68% | US$ 104,14M | 2026-04-24 |
| USVP Management Company, LLC | Institution | 3.171.062 | 3,68% | US$ 104,14M | 2026-04-24 |
| Martis Capital Management, LLC | Institution | 2.243.532 | 2,60% | US$ 73,68M | 2025-08-08 |
| Janus Henderson Group plc | Institution | 2.180.976 | 2,53% | US$ 71,62M | 2026-03-31 |
| HealthCor Management L.P. | Institution | 2.082.014 | 2,41% | US$ 68,37M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 2.045.938 | 2,37% | US$ 67,19M | 2026-03-31 |
| Invesco Ltd. | Institution | 1.912.288 | 2,22% | US$ 62,80M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 1.893.495 | 2,20% | US$ 62,18M | 2026-03-31 |
| UBS Asset Management AG | Institution | 1.843.912 | 2,14% | US$ 60,55M | 2026-03-31 |
| BlackRock, Inc. | Institution | 1.462.584 | 1,70% | US$ 48,03M | 2026-03-31 |
| British Columbia Investment Management Corporation | Institution | 1.367.960 | 1,59% | US$ 44,92M | 2026-04-24 |
| HealthCor Partners Fund, L.P. | Institution | 1.248.939 | 1,45% | US$ 41,02M | 2026-03-24 |
| AllianceBernstein L.P. | Institution | 1.224.326 | 1,42% | US$ 40,21M | 2026-03-31 |
| Millennium Management LLC | Institution | 1.093.417 | 1,27% | US$ 35,91M | 2026-03-31 |
| Baillie Gifford & Co. | Institution | 1.084.652 | 1,26% | US$ 35,62M | 2026-03-31 |
| Dr. Charles Taylor | Insider | 952.907 | 1,10% | US$ 31,29M | 2025-08-08 |
| Summit Partners Public Asset Management, LLC | Institution | 892.093 | 1,03% | US$ 29,30M | 2026-03-31 |
| HealthCor Partners Fund II LP | Institution | 833.075 | 0,97% | US$ 27,36M | 2026-03-24 |
| Franklin Resources, Inc. | Institution | 793.721 | 0,92% | US$ 26,07M | 2026-03-31 |
| Eventide Asset Management, LLC | Institution | 756.956 | 0,88% | US$ 24,86M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 756.605 | 0,88% | US$ 24,85M | 2026-03-31 |
| Eaton Vance Management | Institution | 737.170 | 0,85% | US$ 24,21M | 2026-03-31 |
| Voya Investment Management LLC | Institution | 727.667 | 0,84% | US$ 23,90M | 2026-03-31 |
| Ensign Peak Advisors, Inc. | Institution | 690.466 | 0,80% | US$ 22,67M | 2026-03-31 |
| Next Century Growth Investors LLC | Institution | 652.969 | 0,76% | US$ 21,44M | 2026-03-31 |
| 12 West Capital Management LP | Institution | 640.000 | 0,74% | US$ 21,02M | 2026-03-31 |
| Fred Alger Management, LLC | Institution | 638.306 | 0,74% | US$ 20,96M | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 572.500 | 0,66% | US$ 18,80M | 2026-03-31 |