| RA Capital Management, L.P. | Institution | 6.116.140 | 12,59% | US$ 2,63M | 2026-05-12 |
| RA Capital Healthcare Fund, L.P. | Institution | 5.709.858 | 11,75% | US$ 2,46M | 2026-05-12 |
| Longwood Fund III, L.P. | Institution | 1.677.082 | 3,45% | US$ 721,15k | 2025-12-31 |
| Longwood Fund | Institution | 1.677.082 | 3,45% | US$ 721,15k | 2025-12-31 |
| Vanguard Capital Management, LLC | Institution | 1.217.976 | 2,51% | US$ 523,73k | 2026-03-31 |
| MPM BioImpact LLC | Institution | 1.171.175 | 2,41% | US$ 503,61k | 2026-05-12 |
| Dr. Luke Evnin | Insider | 1.126.496 | 2,32% | US$ 484,39k | 2026-05-13 |
| MPM Bioventures 2014, L.P. | Institution | 845.094 | 1,74% | US$ 363,39k | 2026-05-12 |
| Lynx1 Capital Management LP | Institution | 657.786 | 1,35% | US$ 282,85k | 2026-03-31 |
| UBS Oncology Impact Fund | Institution | 655.471 | 1,35% | US$ 281,85k | 2026-05-12 |
| BioImpact Capital LLC | Institution | 655.471 | 1,35% | US$ 281,85k | 2026-05-12 |
| Dr. Daniel Hicklin | Insider | 647.047 | 1,33% | US$ 278,23k | 2025-04-14 |
| Sphera Funds Management Ltd | Institution | 626.810 | 1,29% | US$ 269,53k | 2026-03-31 |
| DC Investments Management, LLC | Institution | 589.102 | 1,21% | US$ 253,31k | 2026-03-31 |
| Squadron Capital Management Llc | Institution | 563.535 | 1,16% | US$ 242,32k | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 516.218 | 1,06% | US$ 221,97k | 2026-03-31 |
| RA Capital Nexus Fund II, L.P. | Institution | 406.282 | 0,84% | US$ 174,70k | 2026-05-12 |
| Geode Capital Management, LLC | Institution | 389.487 | 0,80% | US$ 167,48k | 2026-03-31 |
| Merrill Lynch, Pierce, Fenner & Smith Incorporated | Institution | 241.034 | 0,50% | US$ 103,64k | 2026-03-31 |
| MPM Oncology Innovations Fund LP | Institution | 173.334 | 0,36% | US$ 74,53k | 2026-05-12 |
| Vanguard Fiduciary Trust Company | Institution | 157.726 | 0,32% | US$ 67,82k | 2026-03-31 |
| Millennium Management LLC | Institution | 132.050 | 0,27% | US$ 56,78k | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 119.168 | 0,25% | US$ 51,24k | 2026-03-31 |
| BlackRock, Inc. | Institution | 101.608 | 0,21% | US$ 43,69k | 2026-03-31 |
| Northern Trust Global Investments | Institution | 86.851 | 0,18% | US$ 37,35k | 2026-03-31 |
| Alyeska Investment Group, L.P. | Institution | 86.554 | 0,18% | US$ 37,22k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 82.836 | 0,17% | US$ 35,62k | 2026-03-31 |
| Bridgeway Capital Management, LLC | Institution | 77.000 | 0,16% | US$ 33,11k | 2026-03-31 |
| BBVA Asset Management, S.A., S.G.I.I.C | Institution | 70.032 | 0,14% | US$ 30,11k | 2025-06-30 |
| UBS Asset Management AG | Institution | 66.857 | 0,14% | US$ 28,75k | 2026-03-31 |
| XTX Markets Limited | Institution | 50.929 | 0,10% | US$ 21,90k | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 38.266 | 0,08% | US$ 16,45k | 2026-03-31 |
| Morgan Stanley | Institution | 33.799 | 0,07% | US$ 14,53k | 2026-03-31 |
| Simplex Trading, LLC | Institution | 32.526 | 0,07% | US$ 13,99k | 2026-03-31 |
| Verdad Advisers, L.P. | Institution | 29.760 | 0,06% | US$ 12,80k | 2026-03-31 |
| MPM BioVentures IV, L.P. | Institution | 27.267 | 0,06% | US$ 11,72k | 2026-05-12 |
| Bank of America Corporation | Institution | 23.549 | 0,05% | US$ 10,13k | 2026-03-31 |
| Raymond James Financial, Inc. | Institution | 19.778 | 0,04% | US$ 8,50k | 2026-03-31 |
| Hudson River Trading LLC | Institution | 17.861 | 0,04% | US$ 7,68k | 2026-03-31 |
| Dr. Briggs Duncan W. Morrison | Insider | 15.523 | 0,03% | US$ 6,67k | 2025-04-14 |
| Certuity, LLC | Institution | 15.000 | 0,03% | US$ 6,45k | 2026-03-31 |
| Delta Investment Management, LLC | Institution | 14.925 | 0,03% | US$ 6,42k | 2026-03-31 |