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| Aktionär | Typ | Gehalten (Tatsächlich) | % Ausstehender Aktien | Marktwert | Positionsdatum |
|---|---|---|---|---|---|
| BlackRock, Inc. | Institution | 8.480.230 | 6,39% | US$ 374,74M | 2026-03-31 |
| Driehaus Capital Management LLC | Institution | 5.911.889 | 4,45% | US$ 261,25M | 2026-03-31 |
| Avoro Capital Advisors LLC | Institution | 5.000.000 | 3,77% | US$ 220,95M | 2026-03-31 |
| Janus Henderson Group plc | Institution | 3.556.041 | 2,68% | US$ 157,14M | 2026-03-31 |
| Deep Track Capital, LP | Institution | 3.000.000 | 2,26% | US$ 132,57M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 2.495.399 | 1,88% | US$ 110,27M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 2.471.873 | 1,86% | US$ 109,23M | 2026-03-31 |
| Octagon Capital Advisors LP | Institution | 2.440.000 | 1,84% | US$ 107,82M | 2026-03-31 |
| Commodore Capital LP | Institution | 2.000.000 | 1,51% | US$ 88,38M | 2026-03-31 |
| FMR LLC | Institution | 1.808.453 | 1,36% | US$ 79,92M | 2026-03-31 |
| Trails Edge Capital Partners, LP | Institution | 1.738.110 | 1,31% | US$ 76,81M | 2026-03-31 |
| Deep Track Biotechnology Master Fund, Ltd | Institution | 1.676.540 | 1,26% | US$ 74,09M | 2025-12-31 |
| ArrowMark Colorado Holdings, LLC | Institution | 1.594.717 | 1,20% | US$ 70,47M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 1.333.442 | 1,00% | US$ 58,92M | 2026-03-31 |
| Wellington Management Group LLP | Institution | 1.304.749 | 0,98% | US$ 57,66M | 2026-03-31 |
| Candriam, Société En Commandite Par Actions | Institution | 1.293.629 | 0,97% | US$ 57,17M | 2026-03-31 |
| Balyasny Asset Management L.P. | Institution | 1.274.221 | 0,96% | US$ 56,31M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 1.201.610 | 0,91% | US$ 53,10M | 2026-03-31 |
| Marshall Wace LLP | Institution | 1.200.825 | 0,90% | US$ 53,06M | 2026-03-31 |
| The Goldman Sachs Group, Inc. | Institution | 1.172.966 | 0,88% | US$ 51,83M | 2026-03-31 |
| Adage Capital Management, L.P. | Institution | 1.150.000 | 0,87% | US$ 50,82M | 2026-03-31 |
| Mr. Robert Barrow | Insider | 1.098.246 | 0,83% | US$ 48,53M | 2026-06-25 |
| Vanguard Capital Management, LLC | Institution | 1.096.978 | 0,83% | US$ 48,48M | 2026-03-31 |
| Holocene Advisors, LP | Institution | 1.091.967 | 0,82% | US$ 48,25M | 2026-03-31 |
| AWM Investment Company Inc | Institution | 1.076.893 | 0,81% | US$ 47,59M | 2026-03-31 |
| Catalio Capital Management, LP | Institution | 1.037.984 | 0,78% | US$ 45,87M | 2026-03-31 |
| Columbia Management Investment Advisers, LLC | Institution | 966.608 | 0,73% | US$ 42,71M | 2026-03-31 |
| Artal Group S.A. | Institution | 919.493 | 0,69% | US$ 40,63M | 2026-03-31 |
| Vanguard Portfolio Management, LLC | Institution | 872.665 | 0,66% | US$ 38,56M | 2026-03-31 |
| Millennium Management LLC | Institution | 846.896 | 0,64% | US$ 37,42M | 2026-03-31 |
| Charles Schwab Investment Management, Inc. | Institution | 808.715 | 0,61% | US$ 35,74M | 2026-03-31 |
| OrbiMed Advisors LLC | Institution | 804.000 | 0,61% | US$ 35,53M | 2026-03-31 |
| Northern Trust Global Investments | Institution | 798.987 | 0,60% | US$ 35,31M | 2026-03-31 |
| BNY Asset Management | Institution | 752.922 | 0,57% | US$ 33,27M | 2026-03-31 |
| Woodline Partners LP | Institution | 752.792 | 0,57% | US$ 33,27M | 2026-03-31 |
| Teachers Insurance and Annuity Association-College Retirement Equities Fund | Institution | 686.895 | 0,52% | US$ 30,35M | 2026-03-31 |
| Eventide Asset Management, LLC | Institution | 686.162 | 0,52% | US$ 30,32M | 2026-03-31 |
| Boxer Capital Management, LLC | Institution | 598.500 | 0,45% | US$ 26,45M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 575.937 | 0,43% | US$ 25,45M | 2026-03-31 |
| Ensign Peak Advisors, Inc. | Institution | 546.783 | 0,41% | US$ 24,16M | 2026-03-31 |
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