| Wellington Management Group LLP | Institution | 8.560.476 | 10,91% | US$ 314,85M | 2026-03-31 |
| Kynam Capital Management, LP | Institution | 5.840.567 | 7,44% | US$ 214,82M | 2026-03-31 |
| Point72 Asset Management, L.P. | Institution | 3.229.939 | 4,11% | US$ 118,80M | 2026-03-31 |
| Commodore Capital Master LP | Institution | 3.028.335 | 3,86% | US$ 111,38M | 2025-09-30 |
| Commodore Capital LP | Institution | 2.696.616 | 3,44% | US$ 99,18M | 2026-03-31 |
| Eversept Partners, L.P. | Institution | 1.788.016 | 2,28% | US$ 65,76M | 2026-03-31 |
| Point72 Associates, LLC | Institution | 1.758.357 | 2,24% | US$ 64,67M | 2025-12-31 |
| Braidwell LP | Institution | 1.356.082 | 1,73% | US$ 49,88M | 2026-03-31 |
| Deep Track Capital, LP | Institution | 1.283.979 | 1,64% | US$ 47,22M | 2026-03-31 |
| Millennium Management LLC | Institution | 1.253.532 | 1,60% | US$ 46,10M | 2026-03-31 |
| Vestal Point Capital, LP | Institution | 1.224.165 | 1,56% | US$ 45,02M | 2026-03-31 |
| Bellevue Asset Management AG | Institution | 1.200.000 | 1,53% | US$ 44,14M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 1.059.534 | 1,35% | US$ 38,97M | 2026-03-31 |
| Eventide Asset Management, LLC | Institution | 1.037.000 | 1,32% | US$ 38,14M | 2026-03-31 |
| Pictet Asset Management Limited | Institution | 923.696 | 1,18% | US$ 33,97M | 2026-03-31 |
| Elmind Capital, L.P. | Institution | 865.000 | 1,10% | US$ 31,81M | 2026-03-31 |
| Bank of America Corporation | Institution | 698.502 | 0,89% | US$ 25,69M | 2026-03-31 |
| Baker Bros. Advisors LP | Institution | 665.370 | 0,85% | US$ 24,47M | 2026-03-31 |
| Rock Springs Capital Management LP | Institution | 650.270 | 0,83% | US$ 23,92M | 2026-03-31 |
| Woodline Partners LP | Institution | 500.127 | 0,64% | US$ 18,39M | 2026-03-31 |
| Affinity Asset Advisors, LLC | Institution | 500.000 | 0,64% | US$ 18,39M | 2026-03-31 |
| 5AM Venture Management, LLC | Institution | 497.270 | 0,63% | US$ 18,29M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 461.247 | 0,59% | US$ 16,96M | 2026-03-31 |
| Logos Global Management, L.P. | Institution | 450.000 | 0,57% | US$ 16,55M | 2026-03-31 |
| ADAR1 Capital Management, LLC | Institution | 427.816 | 0,55% | US$ 15,74M | 2026-03-31 |
| TSP Capital Management Group, LLC | Institution | 375.127 | 0,48% | US$ 13,80M | 2026-03-31 |
| Kennedy Capital Management LLC | Institution | 352.302 | 0,45% | US$ 12,96M | 2026-03-31 |
| Segall Bryant & Hamill, LLC | Institution | 346.919 | 0,44% | US$ 12,76M | 2026-03-31 |