| Jennison Associates LLC | Institution | 24.267.980 | 14,88% | US$ 70,86M | 2026-05-31 |
| T. Rowe Price Group, Inc. | Institution | 11.522.282 | 7,07% | US$ 33,65M | 2026-03-31 |
| Bain Capital Life Sciences Investors, LLC | Institution | 9.677.125 | 5,93% | US$ 28,26M | 2026-03-31 |
| Bain Capital Life Sciences Fund III, L.P. | Institution | 9.677.125 | 5,93% | US$ 28,26M | 2025-06-30 |
| Adage Capital Management, L.P. | Institution | 8.829.522 | 5,42% | US$ 25,78M | 2026-04-10 |
| Adage Capital Partners, L.P. | Institution | 8.829.522 | 5,42% | US$ 25,78M | 2026-04-10 |
| Millennium Management LLC | Institution | 5.903.281 | 3,62% | US$ 17,24M | 2026-03-31 |
| Cormorant Asset Management, LP | Institution | 5.500.000 | 3,37% | US$ 16,06M | 2026-03-31 |
| Vanguard Capital Management, LLC | Institution | 4.028.991 | 2,47% | US$ 11,76M | 2026-03-31 |
| Two Sigma Investments, LP | Institution | 2.497.917 | 1,53% | US$ 7,29M | 2026-03-31 |
| BlackRock, Inc. | Institution | 2.373.003 | 1,46% | US$ 6,93M | 2026-03-31 |
| Marshall Wace LLP | Institution | 2.179.818 | 1,34% | US$ 6,37M | 2026-03-31 |
| Renaissance Technologies LLC | Institution | 2.036.663 | 1,25% | US$ 5,95M | 2026-03-31 |
| Qube Research & Technologies Ltd | Institution | 1.934.990 | 1,19% | US$ 5,65M | 2026-03-31 |
| Morgan Stanley | Institution | 1.408.152 | 0,86% | US$ 4,11M | 2026-03-31 |
| Opaleye Management Inc. | Institution | 1.380.000 | 0,85% | US$ 4,03M | 2026-03-31 |
| Woodline Partners LP | Institution | 1.250.242 | 0,77% | US$ 3,65M | 2026-03-31 |
| Geode Capital Management, LLC | Institution | 1.133.245 | 0,70% | US$ 3,31M | 2026-03-31 |
| Superstring Capital Management LP | Institution | 1.066.239 | 0,65% | US$ 3,11M | 2026-03-31 |
| Ikarian Capital, LLC | Institution | 900.000 | 0,55% | US$ 2,63M | 2026-03-31 |
| Cantor Fitzgerald Asset Management | Institution | 765.000 | 0,47% | US$ 2,23M | 2026-03-31 |
| Schroder Investment Management Limited | Institution | 756.637 | 0,46% | US$ 2,21M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 740.648 | 0,45% | US$ 2,16M | 2026-03-31 |
| Citadel Multi-Strategy Equities Master Fund Ltd. | Institution | 705.465 | 0,43% | US$ 2,06M | 2025-09-30 |
| The Goldman Sachs Group, Inc. | Institution | 701.396 | 0,43% | US$ 2,05M | 2026-03-31 |
| Burkehill Global Management, LP | Institution | 700.000 | 0,43% | US$ 2,04M | 2026-03-31 |
| UBS Asset Management AG | Institution | 606.664 | 0,37% | US$ 1,77M | 2026-03-31 |
| Vanguard Fiduciary Trust Company | Institution | 570.191 | 0,35% | US$ 1,66M | 2026-03-31 |
| GSA Capital Partners LLP | Institution | 561.726 | 0,34% | US$ 1,64M | 2026-03-31 |
| Kvp Capital Advisors, LP | Institution | 505.431 | 0,31% | US$ 1,48M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 469.978 | 0,29% | US$ 1,37M | 2026-03-31 |
| Raiffeisen Kapitalanlage-Gesellschaft m.b.H. | Institution | 450.000 | 0,28% | US$ 1,31M | 2026-03-31 |
| Almitas Capital LLC | Institution | 337.391 | 0,21% | US$ 985,18k | 2026-03-31 |
| Bank of America Corporation | Institution | 269.257 | 0,17% | US$ 786,23k | 2026-03-31 |
| Bridgeway Capital Management, LLC | Institution | 267.372 | 0,16% | US$ 780,73k | 2026-03-31 |
| Diametric Capital, LP | Institution | 262.831 | 0,16% | US$ 767,47k | 2026-03-31 |
| Jane Street Group, LLC | Institution | 248.594 | 0,15% | US$ 725,89k | 2026-03-31 |