| T. Rowe Price Group, Inc. | Institution | 6.546.641 | 13,40% | US$ 186,51M | 2026-03-31 |
| BlackRock, Inc. | Institution | 6.101.765 | 12,49% | US$ 173,84M | 2026-03-31 |
| Casdin Capital, LLC | Institution | 4.757.165 | 9,74% | US$ 135,53M | 2026-06-04 |
| Casdin Partners Master Fund, L.P. | Institution | 4.757.165 | 9,74% | US$ 135,53M | 2026-06-04 |
| Invesco Ltd. | Institution | 2.276.676 | 4,66% | US$ 64,86M | 2026-03-31 |
| State Street Global Advisors, Inc. | Institution | 1.577.076 | 3,23% | US$ 44,93M | 2026-03-31 |
| FMR LLC | Institution | 1.469.622 | 3,01% | US$ 41,87M | 2026-03-31 |
| Massachusetts Financial Services Company | Institution | 1.197.257 | 2,45% | US$ 34,11M | 2026-03-31 |
| Fred Alger Management, LLC | Institution | 1.079.935 | 2,21% | US$ 30,77M | 2026-03-31 |
| Dimensional Fund Advisors LP | Institution | 1.035.757 | 2,12% | US$ 29,51M | 2026-03-31 |
| Columbia Management Investment Advisers, LLC | Institution | 901.138 | 1,84% | US$ 25,67M | 2026-03-31 |
| Palisade Capital Management, LP | Institution | 758.659 | 1,55% | US$ 21,61M | 2026-03-31 |
| Rockefeller & Co. LLC | Institution | 741.352 | 1,52% | US$ 21,12M | 2026-03-31 |
| Nationwide Fund Advisors | Institution | 739.803 | 1,51% | US$ 21,08M | 2026-03-31 |
| Granahan Investment Management, LLC | Institution | 722.057 | 1,48% | US$ 20,57M | 2026-03-31 |
| Stephens Investment Management Group, LLC | Institution | 673.129 | 1,38% | US$ 19,18M | 2026-03-31 |
| Cramer Rosenthal McGlynn LLC | Institution | 632.812 | 1,30% | US$ 18,03M | 2026-03-31 |
| Royce & Associates, LP | Institution | 584.011 | 1,20% | US$ 16,64M | 2026-03-31 |
| Mutual of America Capital Management LLC | Institution | 572.729 | 1,17% | US$ 16,32M | 2026-03-31 |
| Gagnon Securities, LLC | Institution | 536.512 | 1,10% | US$ 15,29M | 2026-03-31 |
| Voya Investment Management LLC | Institution | 496.937 | 1,02% | US$ 14,16M | 2025-12-31 |
| Curi Capital, LLC | Institution | 426.015 | 0,87% | US$ 12,14M | 2026-03-31 |
| Dr. Aby Mathew | Insider | 388.976 | 0,80% | US$ 11,08M | 2026-06-18 |
| Mr. Roderick de Greef | Insider | 386.596 | 0,79% | US$ 11,01M | 2026-06-18 |
| Next Century Growth Investors LLC | Institution | 361.940 | 0,74% | US$ 10,31M | 2026-03-31 |
| Peregrine Capital Management, LLC | Institution | 341.847 | 0,70% | US$ 9,74M | 2026-03-31 |
| Summit Creek Advisors, LLC | Institution | 309.350 | 0,63% | US$ 8,81M | 2026-03-31 |
| Gagnon Advisors, LLC | Institution | 274.217 | 0,56% | US$ 7,81M | 2026-03-31 |
| Ranger Investment Management, L.P. | Institution | 269.365 | 0,55% | US$ 7,67M | 2026-03-31 |
| Russell Investment Management, LLC | Institution | 268.225 | 0,55% | US$ 7,64M | 2026-03-31 |
| Citadel Advisors LLC | Institution | 244.172 | 0,50% | US$ 6,96M | 2026-03-31 |
| Morgan Stanley | Institution | 243.086 | 0,50% | US$ 6,93M | 2026-03-31 |